150 related articles for article (PubMed ID: 34455055)
1. Enhancing Acsl4 in absence of mTORC2/Rictor drove β-cell dedifferentiation via inhibiting FoxO1 and promoting ROS production.
Cui C; Li T; Xie Y; Yang J; Fu C; Qiu Y; Shen L; Ni Q; Wang Q; Nie A; Ning G; Wang W; Gu Y
Biochim Biophys Acta Mol Basis Dis; 2021 Dec; 1867(12):166261. PubMed ID: 34455055
[TBL] [Abstract][Full Text] [Related]
2. Hepatic FOXO1 Target Genes Are Co-regulated by Thyroid Hormone via RICTOR Protein Deacetylation and MTORC2-AKT Protein Inhibition.
Singh BK; Sinha RA; Zhou J; Tripathi M; Ohba K; Wang ME; Astapova I; Ghosh S; Hollenberg AN; Gauthier K; Yen PM
J Biol Chem; 2016 Jan; 291(1):198-214. PubMed ID: 26453307
[TBL] [Abstract][Full Text] [Related]
3. Non-canonical mTORC2 Signaling Regulates Brown Adipocyte Lipid Catabolism through SIRT6-FoxO1.
Jung SM; Hung CM; Hildebrand SR; Sanchez-Gurmaches J; Martinez-Pastor B; Gengatharan JM; Wallace M; Mukhopadhyay D; Martinez Calejman C; Luciano AK; Hsiao WY; Tang Y; Li H; Daniels DL; Mostoslavsky R; Metallo CM; Guertin DA
Mol Cell; 2019 Aug; 75(4):807-822.e8. PubMed ID: 31442424
[TBL] [Abstract][Full Text] [Related]
4. Rictor/mTORC2 is essential for maintaining a balance between beta-cell proliferation and cell size.
Gu Y; Lindner J; Kumar A; Yuan W; Magnuson MA
Diabetes; 2011 Mar; 60(3):827-37. PubMed ID: 21266327
[TBL] [Abstract][Full Text] [Related]
5. The mTORC2/PKC pathway sustains compensatory insulin secretion of pancreatic β cells in response to metabolic stress.
Xie Y; Cui C; Nie A; Wang Y; Ni Q; Liu Y; Yin Q; Zhang H; Li Y; Wang Q; Gu Y; Ning G
Biochim Biophys Acta Gen Subj; 2017 Aug; 1861(8):2039-2047. PubMed ID: 28435021
[TBL] [Abstract][Full Text] [Related]
6. RBM45 reprograms lipid metabolism promoting hepatocellular carcinoma via Rictor and ACSL1/ACSL4.
Wang C; Chen Z; Yi Y; Ding Y; Xu F; Kang H; Lin K; Shu X; Zhong Z; Zhang Z; Liu J; Xu Z; Liu L; He X; Chang Y; Zhao Q
Oncogene; 2024 Jan; 43(5):328-340. PubMed ID: 38040804
[TBL] [Abstract][Full Text] [Related]
7. Mammalian target of rapamycin complex 2 (mTORC2) negatively regulates Toll-like receptor 4-mediated inflammatory response via FoxO1.
Brown J; Wang H; Suttles J; Graves DT; Martin M
J Biol Chem; 2011 Dec; 286(52):44295-305. PubMed ID: 22045807
[TBL] [Abstract][Full Text] [Related]
8. Two distinct mTORC2-dependent pathways converge on Rac1 to drive breast cancer metastasis.
Morrison Joly M; Williams MM; Hicks DJ; Jones B; Sanchez V; Young CD; Sarbassov DD; Muller WJ; Brantley-Sieders D; Cook RS
Breast Cancer Res; 2017 Jun; 19(1):74. PubMed ID: 28666462
[TBL] [Abstract][Full Text] [Related]
9. Diminished acyl-CoA synthetase isoform 4 activity in INS 832/13 cells reduces cellular epoxyeicosatrienoic acid levels and results in impaired glucose-stimulated insulin secretion.
Klett EL; Chen S; Edin ML; Li LO; Ilkayeva O; Zeldin DC; Newgard CB; Coleman RA
J Biol Chem; 2013 Jul; 288(30):21618-29. PubMed ID: 23766516
[TBL] [Abstract][Full Text] [Related]
10. mTORC1 and mTORC2 regulate insulin secretion through Akt in INS-1 cells.
Le Bacquer O; Queniat G; Gmyr V; Kerr-Conte J; Lefebvre B; Pattou F
J Endocrinol; 2013 Jan; 216(1):21-9. PubMed ID: 23092880
[TBL] [Abstract][Full Text] [Related]
11. Elovl5 regulates the mTORC2-Akt-FOXO1 pathway by controlling hepatic cis-vaccenic acid synthesis in diet-induced obese mice.
Tripathy S; Jump DB
J Lipid Res; 2013 Jan; 54(1):71-84. PubMed ID: 23099444
[TBL] [Abstract][Full Text] [Related]
12. mTORC2 negatively controls the maturation process of medullary thymic epithelial cells by inhibiting the LTβR/RANK-NF-κB axis.
Liang Z; Zhang Q; Dong X; Zhang Z; Wang H; Zhang J; Zhao Y
J Cell Physiol; 2021 Jun; 236(6):4725-4737. PubMed ID: 33269476
[TBL] [Abstract][Full Text] [Related]
13. mTORC2/AKT/HSF1/HuR constitute a feed-forward loop regulating Rictor expression and tumor growth in glioblastoma.
Holmes B; Benavides-Serrato A; Freeman RS; Landon KA; Bashir T; Nishimura RN; Gera J
Oncogene; 2018 Feb; 37(6):732-743. PubMed ID: 29059166
[TBL] [Abstract][Full Text] [Related]
14. Inhibition of mTORC2/RICTOR Impairs Melanoma Hepatic Metastasis.
Schmidt KM; Dietrich P; Hackl C; Guenzle J; Bronsert P; Wagner C; Fichtner-Feigl S; Schlitt HJ; Geissler EK; Hellerbrand C; Lang SA
Neoplasia; 2018 Dec; 20(12):1198-1208. PubMed ID: 30404068
[TBL] [Abstract][Full Text] [Related]
15. Down regulation of Peroxiredoxin-3 in 3T3-L1 adipocytes leads to oxidation of Rictor in the mammalian-target of rapamycin complex 2 (mTORC2).
Olson DH; Burrill JS; Kuzmicic J; Hahn WS; Park JM; Kim DH; Bernlohr DA
Biochem Biophys Res Commun; 2017 Nov; 493(3):1311-1317. PubMed ID: 28986255
[TBL] [Abstract][Full Text] [Related]
16. Rictor/mTORC2 deficiency enhances keratinocyte stress tolerance via mitohormesis.
Tassone B; Saoncella S; Neri F; Ala U; Brusa D; Magnuson MA; Provero P; Oliviero S; Riganti C; Calautti E
Cell Death Differ; 2017 Apr; 24(4):731-746. PubMed ID: 28211872
[TBL] [Abstract][Full Text] [Related]
17. An inhibitor-mediated beta-cell dedifferentiation model reveals distinct roles for FoxO1 in glucagon repression and insulin maturation.
Casteels T; Zhang Y; Frogne T; Sturtzel C; Lardeau CH; Sen I; Liu X; Hong S; Pauler FM; Penz T; Brandstetter M; Barbieux C; Berishvili E; Heuser T; Bock C; Riedel CG; Meyer D; Distel M; Hecksher-Sørensen J; Li J; Kubicek S
Mol Metab; 2021 Dec; 54():101329. PubMed ID: 34454092
[TBL] [Abstract][Full Text] [Related]
18. Rictor/mTORC2 involves mitochondrial function in ES cells derived cardiomyocytes via mitochondrial Connexin 43.
Wang JD; Shao Y; Liu D; Liu NY; Zhu DY
Acta Pharmacol Sin; 2021 Nov; 42(11):1790-1797. PubMed ID: 33547375
[TBL] [Abstract][Full Text] [Related]
19. Rapamycin and mTORC2 inhibition synergistically reduce contraction-stimulated muscle protein synthesis.
Ogasawara R; Knudsen JR; Li J; Ato S; Jensen TE
J Physiol; 2020 Dec; 598(23):5453-5466. PubMed ID: 32893874
[TBL] [Abstract][Full Text] [Related]
20. Down-regulation of Rictor enhances cell sensitivity to PI3K inhibitor LY294002 by blocking mTORC2-medicated phosphorylation of Akt/PRAS40 in esophageal squamous cell carcinoma.
Hou G; Zhao Q; Zhang M; Fan T; Liu M; Shi X; Ren Y; Wang Y; Zhou J; Lu Z
Biomed Pharmacother; 2018 Oct; 106():1348-1356. PubMed ID: 30119206
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]