BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

234 related articles for article (PubMed ID: 34459035)

  • 21. REST-dependent downregulation of von Hippel-Lindau tumor suppressor promotes autophagy in SHH-medulloblastoma.
    Singh A; Cheng D; Swaminathan J; Yang Y; Zheng Y; Gordon N; Gopalakrishnan V
    Sci Rep; 2024 Jun; 14(1):13596. PubMed ID: 38866867
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Oxygen-dependent Regulation of Erythropoietin Receptor Turnover and Signaling.
    Heir P; Srikumar T; Bikopoulos G; Bunda S; Poon BP; Lee JE; Raught B; Ohh M
    J Biol Chem; 2016 Apr; 291(14):7357-72. PubMed ID: 26846855
    [TBL] [Abstract][Full Text] [Related]  

  • 23. UBE2M Is a Stress-Inducible Dual E2 for Neddylation and Ubiquitylation that Promotes Targeted Degradation of UBE2F.
    Zhou W; Xu J; Tan M; Li H; Li H; Wei W; Sun Y
    Mol Cell; 2018 Jun; 70(6):1008-1024.e6. PubMed ID: 29932898
    [TBL] [Abstract][Full Text] [Related]  

  • 24. CAND1 inhibits Cullin-2-RING ubiquitin ligases for enhanced substrate specificity.
    Wang K; Diaz S; Li L; Lohman JR; Liu X
    Nat Struct Mol Biol; 2024 Feb; 31(2):323-335. PubMed ID: 38177676
    [TBL] [Abstract][Full Text] [Related]  

  • 25. MLN4924 (Pevonedistat), a protein neddylation inhibitor, suppresses proliferation and migration of human clear cell renal cell carcinoma.
    Tong S; Si Y; Yu H; Zhang L; Xie P; Jiang W
    Sci Rep; 2017 Jul; 7(1):5599. PubMed ID: 28717191
    [TBL] [Abstract][Full Text] [Related]  

  • 26. The NEDD8-activating enzyme inhibitor MLN4924 reduces ischemic brain injury in mice.
    Yu H; Luo H; Chang L; Wang S; Geng X; Kang L; Zhong Y; Cao Y; Wang R; Yang X; Zhu Y; Shi MJ; Hu Y; Liu Z; Yin X; Ran Y; Yang H; Fan W; Zhao BQ
    Proc Natl Acad Sci U S A; 2022 Feb; 119(6):. PubMed ID: 35101976
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Neddylation-induced conformational control regulates cullin RING ligase activity in vivo.
    Boh BK; Smith PG; Hagen T
    J Mol Biol; 2011 Jun; 409(2):136-45. PubMed ID: 21463634
    [TBL] [Abstract][Full Text] [Related]  

  • 28. MLN4924 is an efficient inhibitor of NEDD8 conjugation in plants.
    Hakenjos JP; Richter R; Dohmann EM; Katsiarimpa A; Isono E; Schwechheimer C
    Plant Physiol; 2011 Jun; 156(2):527-36. PubMed ID: 21527421
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Stabilization of HIF through inhibition of Cullin-2 neddylation is protective in mucosal inflammatory responses.
    Curtis VF; Ehrentraut SF; Campbell EL; Glover LE; Bayless A; Kelly CJ; Kominsky DJ; Colgan SP
    FASEB J; 2015 Jan; 29(1):208-15. PubMed ID: 25326537
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Inactivation of the Cullin (CUL)-RING E3 ligase by the NEDD8-activating enzyme inhibitor MLN4924 triggers protective autophagy in cancer cells.
    Luo Z; Pan Y; Jeong LS; Liu J; Jia L
    Autophagy; 2012 Nov; 8(11):1677-9. PubMed ID: 22874562
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Assembly and Regulation of CRL Ubiquitin Ligases.
    Wang K; Deshaies RJ; Liu X
    Adv Exp Med Biol; 2020; 1217():33-46. PubMed ID: 31898220
    [TBL] [Abstract][Full Text] [Related]  

  • 32. CBS9106-induced CRM1 degradation is mediated by cullin ring ligase activity and the neddylation pathway.
    Saito N; Sakakibara K; Sato T; Friedman JM; Kufe DW; VonHoff DD; Kawabe T
    Mol Cancer Ther; 2014 Dec; 13(12):3013-23. PubMed ID: 25253782
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Neddylation inhibitor MLN4924 suppresses growth and migration of human gastric cancer cells.
    Lan H; Tang Z; Jin H; Sun Y
    Sci Rep; 2016 Apr; 6():24218. PubMed ID: 27063292
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Suppression of tumor angiogenesis by targeting the protein neddylation pathway.
    Yao WT; Wu JF; Yu GY; Wang R; Wang K; Li LH; Chen P; Jiang YN; Cheng H; Lee HW; Yu J; Qi H; Yu XJ; Wang P; Chu YW; Yang M; Hua ZC; Ying HQ; Hoffman RM; Jeong LS; Jia LJ
    Cell Death Dis; 2014 Feb; 5(2):e1059. PubMed ID: 24525735
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Destabilization of CDC6 upon DNA damage is dependent on neddylation but independent of Cullin E3 ligases.
    Tan CY; Hagen T
    Int J Biochem Cell Biol; 2013 Jul; 45(7):1489-98. PubMed ID: 23597704
    [TBL] [Abstract][Full Text] [Related]  

  • 36. SENP8 limits aberrant neddylation of NEDD8 pathway components to promote cullin-RING ubiquitin ligase function.
    Coleman KE; Békés M; Chapman JR; Crist SB; Jones MJ; Ueberheide BM; Huang TT
    Elife; 2017 May; 6():. PubMed ID: 28475037
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Targeting protein neddylation with an NEDD8-activating enzyme inhibitor MLN4924 induced apoptosis or senescence in human lymphoma cells.
    Wang Y; Luo Z; Pan Y; Wang W; Zhou X; Jeong LS; Chu Y; Liu J; Jia L
    Cancer Biol Ther; 2015; 16(3):420-9. PubMed ID: 25782162
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Expression and purification of functional recombinant CUL2•RBX1 from E. coli.
    Diaz S; Li L; Wang K; Liu X
    Sci Rep; 2021 May; 11(1):11224. PubMed ID: 34045610
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Rbx1 flexible linker facilitates cullin-RING ligase function before neddylation and after deneddylation.
    Liu J; Nussinov R
    Biophys J; 2010 Aug; 99(3):736-44. PubMed ID: 20682250
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Targeting the neddylation pathway in cells as a potential therapeutic approach for diseases.
    Ying J; Zhang M; Qiu X; Lu Y
    Cancer Chemother Pharmacol; 2018 May; 81(5):797-808. PubMed ID: 29450620
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 12.