162 related articles for article (PubMed ID: 34470783)
21. RSPO2 inhibition of RNF43 and ZNRF3 governs limb development independently of LGR4/5/6.
Szenker-Ravi E; Altunoglu U; Leushacke M; Bosso-Lefèvre C; Khatoo M; Thi Tran H; Naert T; Noelanders R; Hajamohideen A; Beneteau C; de Sousa SB; Karaman B; Latypova X; Başaran S; Yücel EB; Tan TT; Vlaminck L; Nayak SS; Shukla A; Girisha KM; Le Caignec C; Soshnikova N; Uyguner ZO; Vleminckx K; Barker N; Kayserili H; Reversade B
Nature; 2018 May; 557(7706):564-569. PubMed ID: 29769720
[TBL] [Abstract][Full Text] [Related]
22. Structural and molecular basis of ZNRF3/RNF43 transmembrane ubiquitin ligase inhibition by the Wnt agonist R-spondin.
Zebisch M; Xu Y; Krastev C; MacDonald BT; Chen M; Gilbert RJ; He X; Jones EY
Nat Commun; 2013; 4():2787. PubMed ID: 24225776
[TBL] [Abstract][Full Text] [Related]
23. Dishevelled promotes Wnt receptor degradation through recruitment of ZNRF3/RNF43 E3 ubiquitin ligases.
Jiang X; Charlat O; Zamponi R; Yang Y; Cong F
Mol Cell; 2015 May; 58(3):522-33. PubMed ID: 25891077
[TBL] [Abstract][Full Text] [Related]
24. Aberrantly expressed LGR4 empowers Wnt signaling in multiple myeloma by hijacking osteoblast-derived R-spondins.
van Andel H; Ren Z; Koopmans I; Joosten SP; Kocemba KA; de Lau W; Kersten MJ; de Bruin AM; Guikema JE; Clevers H; Spaargaren M; Pals ST
Proc Natl Acad Sci U S A; 2017 Jan; 114(2):376-381. PubMed ID: 28028233
[TBL] [Abstract][Full Text] [Related]
25. LGR4, a G Protein-Coupled Receptor With a Systemic Role: From Development to Metabolic Regulation.
Filipowska J; Kondegowda NG; Leon-Rivera N; Dhawan S; Vasavada RC
Front Endocrinol (Lausanne); 2022; 13():867001. PubMed ID: 35707461
[TBL] [Abstract][Full Text] [Related]
26. R-spondins can potentiate WNT signaling without LGRs.
Lebensohn AM; Rohatgi R
Elife; 2018 Feb; 7():. PubMed ID: 29405118
[TBL] [Abstract][Full Text] [Related]
27. Crystal structure of LGR4-Rspo1 complex: insights into the divergent mechanisms of ligand recognition by leucine-rich repeat G-protein-coupled receptors (LGRs).
Xu JG; Huang C; Yang Z; Jin M; Fu P; Zhang N; Luo J; Li D; Liu M; Zhou Y; Zhu Y
J Biol Chem; 2015 Jan; 290(4):2455-65. PubMed ID: 25480784
[TBL] [Abstract][Full Text] [Related]
28. USP6 oncogene promotes Wnt signaling by deubiquitylating Frizzleds.
Madan B; Walker MP; Young R; Quick L; Orgel KA; Ryan M; Gupta P; Henrich IC; Ferrer M; Marine S; Roberts BS; Arthur WT; Berndt JD; Oliveira AM; Moon RT; Virshup DM; Chou MM; Major MB
Proc Natl Acad Sci U S A; 2016 May; 113(21):E2945-54. PubMed ID: 27162353
[TBL] [Abstract][Full Text] [Related]
29. R-spondins function as ligands of the orphan receptors LGR4 and LGR5 to regulate Wnt/beta-catenin signaling.
Carmon KS; Gong X; Lin Q; Thomas A; Liu Q
Proc Natl Acad Sci U S A; 2011 Jul; 108(28):11452-7. PubMed ID: 21693646
[TBL] [Abstract][Full Text] [Related]
30. SCF
Ci Y; Li X; Chen M; Zhong J; North BJ; Inuzuka H; He X; Li Y; Guo J; Dai X
Protein Cell; 2018 Oct; 9(10):879-889. PubMed ID: 29497989
[TBL] [Abstract][Full Text] [Related]
31. Post-translational Wnt receptor regulation: Is the fog slowly clearing?: The molecular mechanism of RNF43/ZNRF3 ubiquitin ligases is not yet fully elucidated and still controversial.
Tsukiyama T; Koo BK; Hatakeyama S
Bioessays; 2021 Apr; 43(4):e2000297. PubMed ID: 33569855
[TBL] [Abstract][Full Text] [Related]
32. Tumour suppressor RNF43 is a stem-cell E3 ligase that induces endocytosis of Wnt receptors.
Koo BK; Spit M; Jordens I; Low TY; Stange DE; van de Wetering M; van Es JH; Mohammed S; Heck AJ; Maurice MM; Clevers H
Nature; 2012 Aug; 488(7413):665-9. PubMed ID: 22895187
[TBL] [Abstract][Full Text] [Related]
33. Loss of ZNRF3/RNF43 Unleashes EGFR in Cancer.
Yue F; Ku AT; Stevens PD; Michalski MN; Jiang W; Tu J; Shi Z; Dou Y; Wang Y; Feng XH; Hostetter G; Wu X; Huang S; Shroyer NF; Zhang B; Williams BO; Liu Q; Lin X; Li Y
bioRxiv; 2024 Jan; ():. PubMed ID: 38260423
[TBL] [Abstract][Full Text] [Related]
34. The Role of LGR4 (GPR48) in Normal and Cancer Processes.
Ordaz-Ramos A; Rosales-Gallegos VH; Melendez-Zajgla J; Maldonado V; Vazquez-Santillan K
Int J Mol Sci; 2021 Apr; 22(9):. PubMed ID: 33946652
[TBL] [Abstract][Full Text] [Related]
35. A naturally occurring Lgr4 splice variant encodes a soluble antagonist useful for demonstrating the gonadal roles of Lgr4 in mammals.
Hsu PJ; Wu FJ; Kudo M; Hsiao CL; Hsueh AJ; Luo CW
PLoS One; 2014; 9(9):e106804. PubMed ID: 25188337
[TBL] [Abstract][Full Text] [Related]
36. R-spondin-mediated WNT signaling potentiation in mammary and breast cancer development.
Tocci JM; Felcher CM; García Solá ME; Kordon EC
IUBMB Life; 2020 Aug; 72(8):1546-1559. PubMed ID: 32233118
[TBL] [Abstract][Full Text] [Related]
37. R-spondins: Multi-mode WNT signaling regulators in adult stem cells.
Raslan AA; Yoon JK
Int J Biochem Cell Biol; 2019 Jan; 106():26-34. PubMed ID: 30439551
[TBL] [Abstract][Full Text] [Related]
38. Loss of Hepatic Leucine-Rich Repeat-Containing G-Protein Coupled Receptors 4 and 5 Promotes Nonalcoholic Fatty Liver Disease.
Saponara E; Penno C; Orsini V; Wang ZY; Fischer A; Aebi A; Matadamas-Guzman ML; Brun V; Fischer B; Brousseau M; O'Donnell P; Turner J; Graff Meyer A; Bollepalli L; d'Ario G; Roma G; Carbone W; Annunziato S; Obrecht M; Beckmann N; Saravanan C; Osmont A; Tropberger P; Richards SM; Genoud C; Ley S; Ksiazek I; Nigsch F; Terracciano LM; Schadt HS; Bouwmeester T; Tchorz JS; Ruffner H
Am J Pathol; 2023 Feb; 193(2):161-181. PubMed ID: 36410420
[TBL] [Abstract][Full Text] [Related]
39. Lgr4 is crucial for skin carcinogenesis by regulating MEK/ERK and Wnt/β-catenin signaling pathways.
Xu P; Dang Y; Wang L; Liu X; Ren X; Gu J; Liu M; Dai X; Ye X
Cancer Lett; 2016 Dec; 383(2):161-170. PubMed ID: 27693558
[TBL] [Abstract][Full Text] [Related]
40. Lgr4 gene regulates corpus luteum maturation through modulation of the WNT-mediated EGFR-ERK signaling pathway.
Pan H; Cui H; Liu S; Qian Y; Wu H; Li L; Guan Y; Guan X; Zhang L; Fan HY; Ma Y; Li R; Liu M; Li D
Endocrinology; 2014 Sep; 155(9):3624-37. PubMed ID: 24877628
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
