260 related articles for article (PubMed ID: 34473992)
21. Modifiers of Somatic Repeat Instability in Mouse Models of Friedreich Ataxia and the Fragile X-Related Disorders: Implications for the Mechanism of Somatic Expansion in Huntington's Disease.
Zhao X; Kumari D; Miller CJ; Kim GY; Hayward B; Vitalo AG; Pinto RM; Usdin K
J Huntingtons Dis; 2021; 10(1):149-163. PubMed ID: 33579860
[TBL] [Abstract][Full Text] [Related]
22. Antagonistic roles of canonical and Alternative-RPA in disease-associated tandem CAG repeat instability.
Gall-Duncan T; Luo J; Jurkovic CM; Fischer LA; Fujita K; Deshmukh AL; Harding RJ; Tran S; Mehkary M; Li V; Leib DE; Chen R; Tanaka H; Mason AG; Lévesque D; Khan M; Razzaghi M; Prasolava T; Lanni S; Sato N; Caron MC; Panigrahi GB; Wang P; Lau R; Castel AL; Masson JY; Tippett L; Turner C; Spies M; La Spada AR; Campos EI; Curtis MA; Boisvert FM; Faull RLM; Davidson BL; Nakamori M; Okazawa H; Wold MS; Pearson CE
Cell; 2023 Oct; 186(22):4898-4919.e25. PubMed ID: 37827155
[TBL] [Abstract][Full Text] [Related]
23. Parent-of-origin differences of mutant HTT CAG repeat instability in Huntington's disease.
Aziz NA; van Belzen MJ; Coops ID; Belfroid RD; Roos RA
Eur J Med Genet; 2011; 54(4):e413-8. PubMed ID: 21540131
[TBL] [Abstract][Full Text] [Related]
24. Approaches to Sequence the HTT CAG Repeat Expansion and Quantify Repeat Length Variation.
Ciosi M; Cumming SA; Chatzi A; Larson E; Tottey W; Lomeikaite V; Hamilton G; Wheeler VC; Pinto RM; Kwak S; Morton AJ; Monckton DG
J Huntingtons Dis; 2021; 10(1):53-74. PubMed ID: 33579864
[TBL] [Abstract][Full Text] [Related]
25. Genetic Contributors to Intergenerational CAG Repeat Instability in Huntington's Disease Knock-In Mice.
Neto JL; Lee JM; Afridi A; Gillis T; Guide JR; Dempsey S; Lager B; Alonso I; Wheeler VC; Pinto RM
Genetics; 2017 Feb; 205(2):503-516. PubMed ID: 27913616
[TBL] [Abstract][Full Text] [Related]
26. DNA repair in the trinucleotide repeat disorders.
Jones L; Houlden H; Tabrizi SJ
Lancet Neurol; 2017 Jan; 16(1):88-96. PubMed ID: 27979358
[TBL] [Abstract][Full Text] [Related]
27. Continuous and periodic expansion of CAG repeats in Huntington's disease R6/1 mice.
Møllersen L; Rowe AD; Larsen E; Rognes T; Klungland A
PLoS Genet; 2010 Dec; 6(12):e1001242. PubMed ID: 21170307
[TBL] [Abstract][Full Text] [Related]
28. A genetic association study of glutamine-encoding DNA sequence structures, somatic CAG expansion, and DNA repair gene variants, with Huntington disease clinical outcomes.
Ciosi M; Maxwell A; Cumming SA; Hensman Moss DJ; Alshammari AM; Flower MD; Durr A; Leavitt BR; Roos RAC; ; ; Holmans P; Jones L; Langbehn DR; Kwak S; Tabrizi SJ; Monckton DG
EBioMedicine; 2019 Oct; 48():568-580. PubMed ID: 31607598
[TBL] [Abstract][Full Text] [Related]
29. DNA instability in replicating Huntington's disease lymphoblasts.
Cannella M; Maglione V; Martino T; Ragona G; Frati L; Li GM; Squitieri F
BMC Med Genet; 2009 Feb; 10():11. PubMed ID: 19210789
[TBL] [Abstract][Full Text] [Related]
30. Weak strand displacement activity enables human DNA polymerase beta to expand CAG/CTG triplet repeats at strand breaks.
Hartenstine MJ; Goodman MF; Petruska J
J Biol Chem; 2002 Nov; 277(44):41379-89. PubMed ID: 12196536
[TBL] [Abstract][Full Text] [Related]
31. Huntington's disease as caused by 34 CAG repeats.
Andrich J; Arning L; Wieczorek S; Kraus PH; Gold R; Saft C
Mov Disord; 2008 Apr; 23(6):879-81. PubMed ID: 18307262
[TBL] [Abstract][Full Text] [Related]
32. Proliferating cell nuclear antigen prevents trinucleotide repeat expansions by promoting repeat deletion and hairpin removal.
Beaver JM; Lai Y; Rolle SJ; Liu Y
DNA Repair (Amst); 2016 Dec; 48():17-29. PubMed ID: 27793507
[TBL] [Abstract][Full Text] [Related]
33. Neil1 is a genetic modifier of somatic and germline CAG trinucleotide repeat instability in R6/1 mice.
Møllersen L; Rowe AD; Illuzzi JL; Hildrestrand GA; Gerhold KJ; Tveterås L; Bjølgerud A; Wilson DM; Bjørås M; Klungland A
Hum Mol Genet; 2012 Nov; 21(22):4939-47. PubMed ID: 22914735
[TBL] [Abstract][Full Text] [Related]
34. Promotion of somatic CAG repeat expansion by Fan1 knock-out in Huntington's disease knock-in mice is blocked by Mlh1 knock-out.
Loupe JM; Pinto RM; Kim KH; Gillis T; Mysore JS; Andrew MA; Kovalenko M; Murtha R; Seong I; Gusella JF; Kwak S; Howland D; Lee R; Lee JM; Wheeler VC; MacDonald ME
Hum Mol Genet; 2020 Nov; 29(18):3044-3053. PubMed ID: 32876667
[TBL] [Abstract][Full Text] [Related]
35. Age-, tissue- and length-dependent bidirectional somatic CAG•CTG repeat instability in an allelic series of R6/2 Huntington disease mice.
Larson E; Fyfe I; Morton AJ; Monckton DG
Neurobiol Dis; 2015 Apr; 76():98-111. PubMed ID: 25662336
[TBL] [Abstract][Full Text] [Related]
36. The repeat expansion detection method in the analysis of diseases with CAG/CTG repeat expansion: usefulness and limitations.
Martorell L; Pujana MA; Volpini V; Sanchez A; Joven J; Vilella E; Estivill X
Hum Mutat; 1997; 10(6):486-8. PubMed ID: 9401013
[TBL] [Abstract][Full Text] [Related]
37. Investigations of Huntington's Disease and Huntington's Disease-Like Syndromes in Indian Choreatic Patients.
Kaur J; Parveen S; Shamim U; Sharma P; Suroliya V; Sonkar AK; Ahmad I; Garg J; Anand KS; Laskar S; Chowdhury D; Kushwaha S; Goyal V; Srivastava AK; Singh G; Faruq M
J Huntingtons Dis; 2020; 9(3):283-289. PubMed ID: 32675418
[TBL] [Abstract][Full Text] [Related]
38. Novel BAC Mouse Model of Huntington's Disease with 225 CAG Repeats Exhibits an Early Widespread and Stable Degenerative Phenotype.
Wegrzynowicz M; Bichell TJ; Soares BD; Loth MK; McGlothan JS; Mori S; Alikhan FS; Hua K; Coughlin JM; Holt HK; Jetter CS; Pomper MG; Osmand AP; Guilarte TR; Bowman AB
J Huntingtons Dis; 2015; 4(1):17-36. PubMed ID: 26333255
[TBL] [Abstract][Full Text] [Related]
39. Multiple clinical features of Huntington's disease correlate with mutant HTT gene CAG repeat lengths and neurodegeneration.
Podvin S; Reardon HT; Yin K; Mosier C; Hook V
J Neurol; 2019 Mar; 266(3):551-564. PubMed ID: 29956026
[TBL] [Abstract][Full Text] [Related]
40. Loss of TDP-43 promotes somatic CAG repeat expansion in Huntington's disease knock-in mice.
Bai D; Zhu L; Jia Q; Duan X; Chen L; Wang X; Hou J; Jiang G; Yang S; Li S; Li XJ; Yin P
Prog Neurobiol; 2023 Aug; 227():102484. PubMed ID: 37315918
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
