315 related articles for article (PubMed ID: 34473993)
1. Stable maintenance of the Mre11-Rad50-Nbs1 complex is sufficient to restore the DNA double-strand break response in cells lacking RecQL4 helicase activity.
Kim H; Choi H; Im JS; Park SY; Shin G; Yoo JH; Kim G; Lee JK
J Biol Chem; 2021 Oct; 297(4):101148. PubMed ID: 34473993
[TBL] [Abstract][Full Text] [Related]
2. Deubiquitinase USP2 stabilizes the MRE11-RAD50-NBS1 complex at DNA double-strand break sites by counteracting the ubiquitination of NBS1.
Kim H; Kim D; Choi H; Shin G; Lee JK
J Biol Chem; 2023 Jan; 299(1):102752. PubMed ID: 36436562
[TBL] [Abstract][Full Text] [Related]
3. ATM activation is impaired in human cells defective in RecQL4 helicase activity.
Park SY; Kim H; Im JS; Lee JK
Biochem Biophys Res Commun; 2019 Feb; 509(2):379-383. PubMed ID: 30594395
[TBL] [Abstract][Full Text] [Related]
4. C1QBP Promotes Homologous Recombination by Stabilizing MRE11 and Controlling the Assembly and Activation of MRE11/RAD50/NBS1 Complex.
Bai Y; Wang W; Li S; Zhan J; Li H; Zhao M; Zhou XA; Li S; Li X; Huo Y; Shen Q; Zhou M; Zhang H; Luo J; Sung P; Zhu WG; Xu X; Wang J
Mol Cell; 2019 Sep; 75(6):1299-1314.e6. PubMed ID: 31353207
[TBL] [Abstract][Full Text] [Related]
5. RECQL4 Promotes DNA End Resection in Repair of DNA Double-Strand Breaks.
Lu H; Shamanna RA; Keijzers G; Anand R; Rasmussen LJ; Cejka P; Croteau DL; Bohr VA
Cell Rep; 2016 Jun; 16(1):161-173. PubMed ID: 27320928
[TBL] [Abstract][Full Text] [Related]
6. MRE11-RAD50-NBS1 Complex Is Sufficient to Promote Transcription by RNA Polymerase II at Double-Strand Breaks by Melting DNA Ends.
Sharma S; Anand R; Zhang X; Francia S; Michelini F; Galbiati A; Williams H; Ronato DA; Masson JY; Rothenberg E; Cejka P; d'Adda di Fagagna F
Cell Rep; 2021 Jan; 34(1):108565. PubMed ID: 33406426
[TBL] [Abstract][Full Text] [Related]
7. Ataxia telangiectasia-mutated (ATM) kinase activity is regulated by ATP-driven conformational changes in the Mre11/Rad50/Nbs1 (MRN) complex.
Lee JH; Mand MR; Deshpande RA; Kinoshita E; Yang SH; Wyman C; Paull TT
J Biol Chem; 2013 May; 288(18):12840-51. PubMed ID: 23525106
[TBL] [Abstract][Full Text] [Related]
8. Smad7 enhances ATM activity by facilitating the interaction between ATM and Mre11-Rad50-Nbs1 complex in DNA double-strand break repair.
Park S; Kang JM; Kim SJ; Kim H; Hong S; Lee YJ; Kim SJ
Cell Mol Life Sci; 2015 Feb; 72(3):583-596. PubMed ID: 25063542
[TBL] [Abstract][Full Text] [Related]
9. Cell cycle-dependent complex formation of BRCA1.CtIP.MRN is important for DNA double-strand break repair.
Chen L; Nievera CJ; Lee AY; Wu X
J Biol Chem; 2008 Mar; 283(12):7713-20. PubMed ID: 18171670
[TBL] [Abstract][Full Text] [Related]
10. MRE11 UFMylation promotes ATM activation.
Wang Z; Gong Y; Peng B; Shi R; Fan D; Zhao H; Zhu M; Zhang H; Lou Z; Zhou J; Zhu WG; Cong YS; Xu X
Nucleic Acids Res; 2019 May; 47(8):4124-4135. PubMed ID: 30783677
[TBL] [Abstract][Full Text] [Related]
11. Localization of Double-Strand Break Repair Proteins to Viral Replication Compartments following Lytic Reactivation of Kaposi's Sarcoma-Associated Herpesvirus.
Hollingworth R; Horniblow RD; Forrest C; Stewart GS; Grand RJ
J Virol; 2017 Nov; 91(22):. PubMed ID: 28855246
[TBL] [Abstract][Full Text] [Related]
12. Mre11-Rad50-Nbs1 is a keystone complex connecting DNA repair machinery, double-strand break signaling, and the chromatin template.
Williams RS; Williams JS; Tainer JA
Biochem Cell Biol; 2007 Aug; 85(4):509-20. PubMed ID: 17713585
[TBL] [Abstract][Full Text] [Related]
13. ATM-mediated DNA double-strand break response facilitated oncolytic Newcastle disease virus replication and promoted syncytium formation in tumor cells.
Ren S; Ur Rehman Z; Gao B; Yang Z; Zhou J; Meng C; Song C; Nair V; Sun Y; Ding C
PLoS Pathog; 2020 Jun; 16(6):e1008514. PubMed ID: 32479542
[TBL] [Abstract][Full Text] [Related]
14. MRE11 complex links RECQ5 helicase to sites of DNA damage.
Zheng L; Kanagaraj R; Mihaljevic B; Schwendener S; Sartori AA; Gerrits B; Shevelev I; Janscak P
Nucleic Acids Res; 2009 May; 37(8):2645-57. PubMed ID: 19270065
[TBL] [Abstract][Full Text] [Related]
15. [Research Progress in the Roles of MRE11-RAD50-NBS1 Complex and Human Diseases].
Xu XH; Liu YD
Zhongguo Yi Xue Ke Xue Yuan Xue Bao; 2024 Apr; 46(2):232-241. PubMed ID: 38686720
[TBL] [Abstract][Full Text] [Related]
16. MRE11-RAD50-NBS1 complex dictates DNA repair independent of H2AX.
Yuan J; Chen J
J Biol Chem; 2010 Jan; 285(2):1097-104. PubMed ID: 19910469
[TBL] [Abstract][Full Text] [Related]
17. Rad17 recruits the MRE11-RAD50-NBS1 complex to regulate the cellular response to DNA double-strand breaks.
Wang Q; Goldstein M; Alexander P; Wakeman TP; Sun T; Feng J; Lou Z; Kastan MB; Wang XF
EMBO J; 2014 Apr; 33(8):862-77. PubMed ID: 24534091
[TBL] [Abstract][Full Text] [Related]
18. MRNIP condensates promote DNA double-strand break sensing and end resection.
Wang YL; Zhao WW; Bai SM; Feng LL; Bie SY; Gong L; Wang F; Wei MB; Feng WX; Pang XL; Qin CL; Yin XK; Wang YN; Zhou W; Wahl DR; Liu Q; Chen M; Hung MC; Wan XB
Nat Commun; 2022 May; 13(1):2638. PubMed ID: 35551189
[TBL] [Abstract][Full Text] [Related]
19. Rad50 zinc hook is important for the Mre11 complex to bind chromosomal DNA double-stranded breaks and initiate various DNA damage responses.
He J; Shi LZ; Truong LN; Lu CS; Razavian N; Li Y; Negrete A; Shiloach J; Berns MW; Wu X
J Biol Chem; 2012 Sep; 287(38):31747-56. PubMed ID: 22833675
[TBL] [Abstract][Full Text] [Related]
20. ATP puts the brake on DNA double-strand break repair: a new study shows that ATP switches the Mre11-Rad50-Nbs1 repair factor between signaling and processing of DNA ends.
Hopfner KP
Bioessays; 2014 Dec; 36(12):1170-8. PubMed ID: 25213441
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
