These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
2. Rare BRAF mutations in pancreatic neuroendocrine tumors may predict response to RAF and MEK inhibition. Allen A; Qin ACR; Raj N; Wang J; Uddin S; Yao Z; Tang L; Meyers PA; Taylor BS; Berger MF; Yaeger R; Reidy-Lagunes D; Pratilas CA PLoS One; 2019; 14(6):e0217399. PubMed ID: 31158244 [TBL] [Abstract][Full Text] [Related]
3. BRAF Dizdar L; Werner TA; Drusenheimer JC; Möhlendick B; Raba K; Boeck I; Anlauf M; Schott M; Göring W; Esposito I; Stoecklein NH; Knoefel WT; Krieg A Int J Cancer; 2019 Mar; 144(6):1379-1390. PubMed ID: 30144031 [TBL] [Abstract][Full Text] [Related]
4. BRAF-Driven Pancreatic Cancer: Prevalence, Molecular Features, and Therapeutic Opportunities. Ciner AT; Jiang Y; Hausner P Mol Cancer Res; 2023 Apr; 21(4):293-300. PubMed ID: 36534729 [TBL] [Abstract][Full Text] [Related]
5. Classifying BRAF alterations in cancer: new rational therapeutic strategies for actionable mutations. Dankner M; Rose AAN; Rajkumar S; Siegel PM; Watson IR Oncogene; 2018 Jun; 37(24):3183-3199. PubMed ID: 29540830 [TBL] [Abstract][Full Text] [Related]
6. Clinical Acquired Resistance to RAF Inhibitor Combinations in BRAF-Mutant Colorectal Cancer through MAPK Pathway Alterations. Ahronian LG; Sennott EM; Van Allen EM; Wagle N; Kwak EL; Faris JE; Godfrey JT; Nishimura K; Lynch KD; Mermel CH; Lockerman EL; Kalsy A; Gurski JM; Bahl S; Anderka K; Green LM; Lennon NJ; Huynh TG; Mino-Kenudson M; Getz G; Dias-Santagata D; Iafrate AJ; Engelman JA; Garraway LA; Corcoran RB Cancer Discov; 2015 Apr; 5(4):358-67. PubMed ID: 25673644 [TBL] [Abstract][Full Text] [Related]
7. BRAF fusions define a distinct molecular subset of melanomas with potential sensitivity to MEK inhibition. Hutchinson KE; Lipson D; Stephens PJ; Otto G; Lehmann BD; Lyle PL; Vnencak-Jones CL; Ross JS; Pietenpol JA; Sosman JA; Puzanov I; Miller VA; Pao W Clin Cancer Res; 2013 Dec; 19(24):6696-702. PubMed ID: 24345920 [TBL] [Abstract][Full Text] [Related]
8. Diverse Stangl C; Post JB; van Roosmalen MJ; Hami N; Verlaan-Klink I; Vos HR; van Es RM; Koudijs MJ; Voest EE; Snippert HJG; Kloosterman WP Mol Cancer Res; 2020 Apr; 18(4):537-548. PubMed ID: 31911540 [TBL] [Abstract][Full Text] [Related]
9. RAF inhibitor resistance is mediated by dimerization of aberrantly spliced BRAF(V600E). Poulikakos PI; Persaud Y; Janakiraman M; Kong X; Ng C; Moriceau G; Shi H; Atefi M; Titz B; Gabay MT; Salton M; Dahlman KB; Tadi M; Wargo JA; Flaherty KT; Kelley MC; Misteli T; Chapman PB; Sosman JA; Graeber TG; Ribas A; Lo RS; Rosen N; Solit DB Nature; 2011 Nov; 480(7377):387-90. PubMed ID: 22113612 [TBL] [Abstract][Full Text] [Related]
10. ERK mutations confer resistance to mitogen-activated protein kinase pathway inhibitors. Goetz EM; Ghandi M; Treacy DJ; Wagle N; Garraway LA Cancer Res; 2014 Dec; 74(23):7079-89. PubMed ID: 25320010 [TBL] [Abstract][Full Text] [Related]
11. Protein Kinase CK2α Maintains Extracellular Signal-regulated Kinase (ERK) Activity in a CK2α Kinase-independent Manner to Promote Resistance to Inhibitors of RAF and MEK but Not ERK in BRAF Mutant Melanoma. Zhou B; Ritt DA; Morrison DK; Der CJ; Cox AD J Biol Chem; 2016 Aug; 291(34):17804-15. PubMed ID: 27226552 [TBL] [Abstract][Full Text] [Related]
12. RAF inhibitors transactivate RAF dimers and ERK signalling in cells with wild-type BRAF. Poulikakos PI; Zhang C; Bollag G; Shokat KM; Rosen N Nature; 2010 Mar; 464(7287):427-30. PubMed ID: 20179705 [TBL] [Abstract][Full Text] [Related]
13. A Rare p.T599dup BRAF Mutant NSCLC in a Non-Smoker. Turshudzhyan A; Vredenburgh J Curr Oncol; 2020 Dec; 28(1):196-202. PubMed ID: 33704186 [TBL] [Abstract][Full Text] [Related]
14. Relationships among Wan XB; Wang AQ; Cao J; Dong ZC; Li N; Yang S; Sun MM; Li Z; Luo SX World J Gastroenterol; 2019 Feb; 25(7):808-823. PubMed ID: 30809081 [TBL] [Abstract][Full Text] [Related]
15. Nikanjam M; Tinajero J; Barkauskas DA; Kurzrock R Mol Cancer Ther; 2021 Jun; 20(6):1072-1079. PubMed ID: 33722853 [TBL] [Abstract][Full Text] [Related]
16. The Hippo effector YAP promotes resistance to RAF- and MEK-targeted cancer therapies. Lin L; Sabnis AJ; Chan E; Olivas V; Cade L; Pazarentzos E; Asthana S; Neel D; Yan JJ; Lu X; Pham L; Wang MM; Karachaliou N; Cao MG; Manzano JL; Ramirez JL; Torres JM; Buttitta F; Rudin CM; Collisson EA; Algazi A; Robinson E; Osman I; Muñoz-Couselo E; Cortes J; Frederick DT; Cooper ZA; McMahon M; Marchetti A; Rosell R; Flaherty KT; Wargo JA; Bivona TG Nat Genet; 2015 Mar; 47(3):250-6. PubMed ID: 25665005 [TBL] [Abstract][Full Text] [Related]
17. Targeting the multifaceted BRAF in cancer: New directions. Toye E; Chehrazi-Raffle A; Hwang J; Antonarakis ES Oncotarget; 2024 Jul; 15():486-492. PubMed ID: 39018217 [TBL] [Abstract][Full Text] [Related]
18. An oncogenic mutant of RHEB, RHEB Y35N, exhibits an altered interaction with BRAF resulting in cancer transformation. Heard JJ; Phung I; Potes MI; Tamanoi F BMC Cancer; 2018 Jan; 18(1):69. PubMed ID: 29320991 [TBL] [Abstract][Full Text] [Related]
19. Successful BRAF/MEK inhibition in a patient with Busch E; Kreutzfeldt S; Agaimy A; Mechtersheimer G; Horak P; Brors B; Hutter B; Fröhlich M; Uhrig S; Mayer P; Schröck E; Stenzinger A; Glimm H; Jäger D; Springfeld C; Fröhling S; Zschäbitz S Cold Spring Harb Mol Case Stud; 2020 Aug; 6(4):. PubMed ID: 32843432 [TBL] [Abstract][Full Text] [Related]
20. Preclinical efficacy of a RAF inhibitor that evades paradoxical MAPK pathway activation in protein kinase BRAF-mutant lung cancer. Okimoto RA; Lin L; Olivas V; Chan E; Markegard E; Rymar A; Neel D; Chen X; Hemmati G; Bollag G; Bivona TG Proc Natl Acad Sci U S A; 2016 Nov; 113(47):13456-13461. PubMed ID: 27834212 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]