These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

249 related articles for article (PubMed ID: 34477374)

  • 1. Chemical Probes for Understudied Kinases: Challenges and Opportunities.
    Serafim RAM; Elkins JM; Zuercher WJ; Laufer SA; Gehringer M
    J Med Chem; 2022 Jan; 65(2):1132-1170. PubMed ID: 34477374
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Downfalls of Chemical Probes Acting at the Kinase ATP-Site: CK2 as a Case Study.
    Atkinson EL; Iegre J; Brear PD; Zhabina EA; Hyvönen M; Spring DR
    Molecules; 2021 Mar; 26(7):. PubMed ID: 33807474
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Reactive Chemical Probes: Beyond the Kinase Cysteinome.
    Jones LH
    Angew Chem Int Ed Engl; 2018 Jul; 57(30):9220-9223. PubMed ID: 29644769
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Characterizing the role of the dark kinome in neurodegenerative disease - A mini review.
    Axtman AD
    Biochim Biophys Acta Gen Subj; 2021 Dec; 1865(12):130014. PubMed ID: 34547390
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The Cysteinome of Protein Kinases as a Target in Drug Development.
    Chaikuad A; Koch P; Laufer SA; Knapp S
    Angew Chem Int Ed Engl; 2018 Apr; 57(16):4372-4385. PubMed ID: 28994500
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The Clinical Kinase Index: A Method to Prioritize Understudied Kinases as Drug Targets for the Treatment of Cancer.
    Essegian D; Khurana R; Stathias V; Schürer SC
    Cell Rep Med; 2020 Oct; 1(7):100128. PubMed ID: 33205077
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Probing the probes: fitness factors for small molecule tools.
    Workman P; Collins I
    Chem Biol; 2010 Jun; 17(6):561-77. PubMed ID: 20609406
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Pocketome of human kinases: prioritizing the ATP binding sites of (yet) untapped protein kinases for drug discovery.
    Volkamer A; Eid S; Turk S; Jaeger S; Rippmann F; Fulle S
    J Chem Inf Model; 2015 Mar; 55(3):538-49. PubMed ID: 25557645
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Chemical probes of signal-transducing proteins.
    Lawrence DS
    Acc Chem Res; 2003 Jun; 36(6):401-9. PubMed ID: 12809526
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Targeting protein kinases with selective and semipromiscuous covalent inhibitors.
    Miller RM; Taunton J
    Methods Enzymol; 2014; 548():93-116. PubMed ID: 25399643
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Non-kinase targets of protein kinase inhibitors.
    Munoz L
    Nat Rev Drug Discov; 2017 Jun; 16(6):424-440. PubMed ID: 28280261
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Development of Novel In Vivo Chemical Probes to Address CNS Protein Kinase Involvement in Synaptic Dysfunction.
    Watterson DM; Grum-Tokars VL; Roy SM; Schavocky JP; Bradaric BD; Bachstetter AD; Xing B; Dimayuga E; Saeed F; Zhang H; Staniszewski A; Pelletier JC; Minasov G; Anderson WF; Arancio O; Van Eldik LJ
    PLoS One; 2013; 8(6):e66226. PubMed ID: 23840427
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Trends in kinase drug discovery: targets, indications and inhibitor design.
    Attwood MM; Fabbro D; Sokolov AV; Knapp S; Schiöth HB
    Nat Rev Drug Discov; 2021 Nov; 20(11):839-861. PubMed ID: 34354255
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Chemical genomic and proteomic methods for determining kinase inhibitor selectivity.
    Krishnamurty R; Maly DJ
    Comb Chem High Throughput Screen; 2007 Sep; 10(8):652-66. PubMed ID: 18045078
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Proteome-wide discovery of unknown ATP-binding proteins and kinase inhibitor target proteins using an ATP probe.
    Adachi J; Kishida M; Watanabe S; Hashimoto Y; Fukamizu K; Tomonaga T
    J Proteome Res; 2014 Dec; 13(12):5461-70. PubMed ID: 25230287
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A broad activity screen in support of a chemogenomic map for kinase signalling research and drug discovery.
    Gao Y; Davies SP; Augustin M; Woodward A; Patel UA; Kovelman R; Harvey KJ
    Biochem J; 2013 Apr; 451(2):313-28. PubMed ID: 23398362
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Kinome-Wide Profiling Prediction of Small Molecules.
    Sorgenfrei FA; Fulle S; Merget B
    ChemMedChem; 2018 Mar; 13(6):495-499. PubMed ID: 28544552
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Targeting conformational plasticity of protein kinases.
    Tong M; Seeliger MA
    ACS Chem Biol; 2015 Jan; 10(1):190-200. PubMed ID: 25486330
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Crowdsourced mapping of unexplored target space of kinase inhibitors.
    Cichońska A; Ravikumar B; Allaway RJ; Wan F; Park S; Isayev O; Li S; Mason M; Lamb A; Tanoli Z; Jeon M; Kim S; Popova M; Capuzzi S; Zeng J; Dang K; Koytiger G; Kang J; Wells CI; Willson TM; ; Oprea TI; Schlessinger A; Drewry DH; Stolovitzky G; Wennerberg K; Guinney J; Aittokallio T
    Nat Commun; 2021 Jun; 12(1):3307. PubMed ID: 34083538
    [TBL] [Abstract][Full Text] [Related]  

  • 20. System-based drug discovery within the human kinome.
    Bamborough P
    Expert Opin Drug Discov; 2012 Nov; 7(11):1053-70. PubMed ID: 22971083
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.