These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

267 related articles for article (PubMed ID: 34479957)

  • 1. Tumor Cell IDO Enhances Immune Suppression and Decreases Survival Independent of Tryptophan Metabolism in Glioblastoma.
    Zhai L; Bell A; Ladomersky E; Lauing KL; Bollu L; Nguyen B; Genet M; Kim M; Chen P; Mi X; Wu JD; Schipma MJ; Wray B; Griffiths J; Unwin RD; Clark SJ; Acharya R; Bao R; Horbinski C; Lukas RV; Schiltz GE; Wainwright DA
    Clin Cancer Res; 2021 Dec; 27(23):6514-6528. PubMed ID: 34479957
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synergistic antitumor effect with indoleamine 2,3-dioxygenase inhibition and temozolomide in a murine glioma model.
    Hanihara M; Kawataki T; Oh-Oka K; Mitsuka K; Nakao A; Kinouchi H
    J Neurosurg; 2016 Jun; 124(6):1594-601. PubMed ID: 26636389
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Indoleamine 2,3-dioxygenase-1 involves in CD8
    Zhou Y; Yao L; Ma T; Wang Z; Yin Y; Yang J; Zhang X; Zhang M; Qin G; Ma J; Zhao L; Liang J; Zhang J
    Int Immunopharmacol; 2024 Dec; 142(Pt A):113062. PubMed ID: 39244898
    [TBL] [Abstract][Full Text] [Related]  

  • 4. IDO expression in brain tumors increases the recruitment of regulatory T cells and negatively impacts survival.
    Wainwright DA; Balyasnikova IV; Chang AL; Ahmed AU; Moon KS; Auffinger B; Tobias AL; Han Y; Lesniak MS
    Clin Cancer Res; 2012 Nov; 18(22):6110-21. PubMed ID: 22932670
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Advanced Age Increases Immunosuppression in the Brain and Decreases Immunotherapeutic Efficacy in Subjects with Glioblastoma.
    Ladomersky E; Zhai L; Lauing KL; Bell A; Xu J; Kocherginsky M; Zhang B; Wu JD; Podojil JR; Platanias LC; Mochizuki AY; Prins RM; Kumthekar P; Raizer JJ; Dixit K; Lukas RV; Horbinski C; Wei M; Zhou C; Pawelec G; Campisi J; Grohmann U; Prendergast GC; Munn DH; Wainwright DA
    Clin Cancer Res; 2020 Oct; 26(19):5232-5245. PubMed ID: 32546647
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Indoleamine 2,3-dioxygenase as a new target for malignant glioma therapy. Laboratory investigation.
    Miyazaki T; Moritake K; Yamada K; Hara N; Osago H; Shibata T; Akiyama Y; Tsuchiya M
    J Neurosurg; 2009 Aug; 111(2):230-7. PubMed ID: 19199463
    [TBL] [Abstract][Full Text] [Related]  

  • 7. PCC0208009 enhances the anti-tumor effects of temozolomide through direct inhibition and transcriptional regulation of indoleamine 2,3-dioxygenase in glioma models.
    Sun S; Du G; Xue J; Ma J; Ge M; Wang H; Tian J
    Int J Immunopathol Pharmacol; 2018; 32():2058738418787991. PubMed ID: 29993291
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Immunosuppressive IDO in Cancer: Mechanisms of Action, Animal Models, and Targeting Strategies.
    Zhai L; Bell A; Ladomersky E; Lauing KL; Bollu L; Sosman JA; Zhang B; Wu JD; Miller SD; Meeks JJ; Lukas RV; Wyatt E; Doglio L; Schiltz GE; McCusker RH; Wainwright DA
    Front Immunol; 2020; 11():1185. PubMed ID: 32612606
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Non-tumor cell IDO1 predominantly contributes to enzyme activity and response to CTLA-4/PD-L1 inhibition in mouse glioblastoma.
    Zhai L; Ladomersky E; Dostal CR; Lauing KL; Swoap K; Billingham LK; Gritsina G; Wu M; McCusker RH; Binder DC; Wainwright DA
    Brain Behav Immun; 2017 May; 62():24-29. PubMed ID: 28179106
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Distinct effects of human glioblastoma immunoregulatory molecules programmed cell death ligand-1 (PDL-1) and indoleamine 2,3-dioxygenase (IDO) on tumour-specific T cell functions.
    Avril T; Saikali S; Vauleon E; Jary A; Hamlat A; De Tayrac M; Mosser J; Quillien V
    J Neuroimmunol; 2010 Aug; 225(1-2):22-33. PubMed ID: 20493562
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The immunosuppressive role of indoleamine 2, 3-dioxygenase in glioblastoma: mechanism of action and immunotherapeutic strategies.
    Hosseinalizadeh H; Mahmoodpour M; Samadani AA; Roudkenar MH
    Med Oncol; 2022 Jun; 39(9):130. PubMed ID: 35716323
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Durable therapeutic efficacy utilizing combinatorial blockade against IDO, CTLA-4, and PD-L1 in mice with brain tumors.
    Wainwright DA; Chang AL; Dey M; Balyasnikova IV; Kim CK; Tobias A; Cheng Y; Kim JW; Qiao J; Zhang L; Han Y; Lesniak MS
    Clin Cancer Res; 2014 Oct; 20(20):5290-301. PubMed ID: 24691018
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Indoleamine 2,3-dioxygenase regulates anti-tumor immunity in lung cancer by metabolic reprogramming of immune cells in the tumor microenvironment.
    Schafer CC; Wang Y; Hough KP; Sawant A; Grant SC; Thannickal VJ; Zmijewski J; Ponnazhagan S; Deshane JS
    Oncotarget; 2016 Nov; 7(46):75407-75424. PubMed ID: 27705910
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Infiltrating T Cells Increase IDO1 Expression in Glioblastoma and Contribute to Decreased Patient Survival.
    Zhai L; Ladomersky E; Lauing KL; Wu M; Genet M; Gritsina G; Győrffy B; Brastianos PK; Binder DC; Sosman JA; Giles FJ; James CD; Horbinski C; Stupp R; Wainwright DA
    Clin Cancer Res; 2017 Nov; 23(21):6650-6660. PubMed ID: 28751450
    [No Abstract]   [Full Text] [Related]  

  • 15. Activation of the Kynurenine Pathway in Human Malignancies Can Be Suppressed by the Cyclin-Dependent Kinase Inhibitor Dinaciclib.
    Riess C; Schneider B; Kehnscherper H; Gesche J; Irmscher N; Shokraie F; Classen CF; Wirthgen E; Domanska G; Zimpfer A; Strüder D; Junghanss C; Maletzki C
    Front Immunol; 2020; 11():55. PubMed ID: 32117235
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Canine mast cell tumour cells regulate tryptophan catabolism via the expression of indoleamine 2,3-dioxygenase.
    Matsuda A; Hata A; Tanaka A; Matsuda H
    Res Vet Sci; 2021 Jul; 137():159-162. PubMed ID: 33984619
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Indoleamine 2, 3-Dioxygenase Promotes Aryl Hydrocarbon Receptor-Dependent Differentiation Of Regulatory B Cells in Lung Cancer.
    Tousif S; Wang Y; Jackson J; Hough KP; Strenkowski JG; Athar M; Thannickal VJ; McCusker RH; Ponnazhagan S; Deshane JS
    Front Immunol; 2021; 12():747780. PubMed ID: 34867973
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Uveal melanoma expression of indoleamine 2,3-deoxygenase: establishment of an immune privileged environment by tryptophan depletion.
    Chen PW; Mellon JK; Mayhew E; Wang S; He YG; Hogan N; Niederkorn JY
    Exp Eye Res; 2007 Nov; 85(5):617-25. PubMed ID: 17870068
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Imaging tryptophan uptake with positron emission tomography in glioblastoma patients treated with indoximod.
    Lukas RV; Juhász C; Wainwright DA; James CD; Kennedy E; Stupp R; Lesniak MS
    J Neurooncol; 2019 Jan; 141(1):111-120. PubMed ID: 30415456
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Indoleamine 2,3-dioxygenase 1 is highly expressed in glioma stem cells.
    Ozawa Y; Yamamuro S; Sano E; Tatsuoka J; Hanashima Y; Yoshimura S; Sumi K; Hara H; Nakayama T; Suzuki Y; Yoshino A
    Biochem Biophys Res Commun; 2020 Apr; 524(3):723-729. PubMed ID: 32035622
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.