BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

264 related articles for article (PubMed ID: 34481157)

  • 1. The RNF8 and RNF168 Ubiquitin Ligases Regulate Pro- and Anti-Resection Activities at Broken DNA Ends During Non-Homologous End Joining.
    Chen BR; Wang Y; Shen ZJ; Bennett A; Hindi I; Tyler JK; Sleckman BP
    DNA Repair (Amst); 2021 Dec; 108():103217. PubMed ID: 34481157
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Ectopic expression of RNF168 and 53BP1 increases mutagenic but not physiological non-homologous end joining.
    Zong D; Callén E; Pegoraro G; Lukas C; Lukas J; Nussenzweig A
    Nucleic Acids Res; 2015 May; 43(10):4950-61. PubMed ID: 25916843
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Tumors overexpressing RNF168 show altered DNA repair and responses to genotoxic treatments, genomic instability and resistance to proteotoxic stress.
    Chroma K; Mistrik M; Moudry P; Gursky J; Liptay M; Strauss R; Skrott Z; Vrtel R; Bartkova J; Kramara J; Bartek J
    Oncogene; 2017 Apr; 36(17):2405-2422. PubMed ID: 27841863
    [TBL] [Abstract][Full Text] [Related]  

  • 4. RNF8 promotes high linear energy transfer carbon-ion-induced DNA double-stranded break repair in serum-starved human cells.
    Nakajima NI; Yamauchi M; Kakoti S; Cuihua L; Kato R; Permata TBM; Iijima M; Yajima H; Yasuhara T; Yamada S; Hasegawa S; Shibata A
    DNA Repair (Amst); 2020; 91-92():102872. PubMed ID: 32502756
    [TBL] [Abstract][Full Text] [Related]  

  • 5. USP14 regulates DNA damage repair by targeting RNF168-dependent ubiquitination.
    Sharma A; Alswillah T; Singh K; Chatterjee P; Willard B; Venere M; Summers MK; Almasan A
    Autophagy; 2018; 14(11):1976-1990. PubMed ID: 29995557
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Regulation of 53BP1 protein stability by RNF8 and RNF168 is important for efficient DNA double-strand break repair.
    Hu Y; Wang C; Huang K; Xia F; Parvin JD; Mondal N
    PLoS One; 2014; 9(10):e110522. PubMed ID: 25337968
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Ubiquitin-H2AX fusions render 53BP1 recruitment to DNA damage sites independent of RNF8 or RNF168.
    Kocyłowski MK; Rey AJ; Stewart GS; Halazonetis TD
    Cell Cycle; 2015; 14(11):1748-58. PubMed ID: 25695757
    [TBL] [Abstract][Full Text] [Related]  

  • 8. ASF1a Promotes Non-homologous End Joining Repair by Facilitating Phosphorylation of MDC1 by ATM at Double-Strand Breaks.
    Lee KY; Im JS; Shibata E; Dutta A
    Mol Cell; 2017 Oct; 68(1):61-75.e5. PubMed ID: 28943310
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Human RNF169 is a negative regulator of the ubiquitin-dependent response to DNA double-strand breaks.
    Poulsen M; Lukas C; Lukas J; Bekker-Jensen S; Mailand N
    J Cell Biol; 2012 Apr; 197(2):189-99. PubMed ID: 22492721
    [TBL] [Abstract][Full Text] [Related]  

  • 10. RNF8 E3 Ubiquitin Ligase Stimulates Ubc13 E2 Conjugating Activity That Is Essential for DNA Double Strand Break Signaling and BRCA1 Tumor Suppressor Recruitment.
    Hodge CD; Ismail IH; Edwards RA; Hura GL; Xiao AT; Tainer JA; Hendzel MJ; Glover JN
    J Biol Chem; 2016 Apr; 291(18):9396-410. PubMed ID: 26903517
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Histone H1 couples initiation and amplification of ubiquitin signalling after DNA damage.
    Thorslund T; Ripplinger A; Hoffmann S; Wild T; Uckelmann M; Villumsen B; Narita T; Sixma TK; Choudhary C; Bekker-Jensen S; Mailand N
    Nature; 2015 Nov; 527(7578):389-93. PubMed ID: 26503038
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The E3 ligase RNF8 regulates KU80 removal and NHEJ repair.
    Feng L; Chen J
    Nat Struct Mol Biol; 2012 Jan; 19(2):201-6. PubMed ID: 22266820
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Ubiquitin Phosphorylation at Thr12 Modulates the DNA Damage Response.
    Walser F; Mulder MPC; Bragantini B; Burger S; Gubser T; Gatti M; Botuyan MV; Villa A; Altmeyer M; Neri D; Ovaa H; Mer G; Penengo L
    Mol Cell; 2020 Nov; 80(3):423-436.e9. PubMed ID: 33022275
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The deubiquitylating enzyme USP44 counteracts the DNA double-strand break response mediated by the RNF8 and RNF168 ubiquitin ligases.
    Mosbech A; Lukas C; Bekker-Jensen S; Mailand N
    J Biol Chem; 2013 Jun; 288(23):16579-16587. PubMed ID: 23615962
    [TBL] [Abstract][Full Text] [Related]  

  • 15. RNF126 Quenches RNF168 Function in the DNA Damage Response.
    Zhang L; Wang Z; Shi R; Zhu X; Zhou J; Peng B; Xu X
    Genomics Proteomics Bioinformatics; 2018 Dec; 16(6):428-438. PubMed ID: 30529286
    [TBL] [Abstract][Full Text] [Related]  

  • 16. RNF168 ubiquitylates 53BP1 and controls its response to DNA double-strand breaks.
    Bohgaki M; Bohgaki T; El Ghamrasni S; Srikumar T; Maire G; Panier S; Fradet-Turcotte A; Stewart GS; Raught B; Hakem A; Hakem R
    Proc Natl Acad Sci U S A; 2013 Dec; 110(52):20982-7. PubMed ID: 24324146
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Opposing roles of RNF8/RNF168 and deubiquitinating enzymes in ubiquitination-dependent DNA double-strand break response signaling and DNA-repair pathway choice.
    Nakada S
    J Radiat Res; 2016 Aug; 57 Suppl 1(Suppl 1):i33-i40. PubMed ID: 26983989
    [TBL] [Abstract][Full Text] [Related]  

  • 18. RNF8- and RNF168-dependent degradation of KDM4A/JMJD2A triggers 53BP1 recruitment to DNA damage sites.
    Mallette FA; Mattiroli F; Cui G; Young LC; Hendzel MJ; Mer G; Sixma TK; Richard S
    EMBO J; 2012 Apr; 31(8):1865-78. PubMed ID: 22373579
    [TBL] [Abstract][Full Text] [Related]  

  • 19. RNF8 regulates assembly of RAD51 at DNA double-strand breaks in the absence of BRCA1 and 53BP1.
    Nakada S; Yonamine RM; Matsuo K
    Cancer Res; 2012 Oct; 72(19):4974-83. PubMed ID: 22865450
    [TBL] [Abstract][Full Text] [Related]  

  • 20. RNF8 has both KU-dependent and independent roles in chromosomal break repair.
    Tsai LJ; Lopezcolorado FW; Bhargava R; Mendez-Dorantes C; Jahanshir E; Stark JM
    Nucleic Acids Res; 2020 Jun; 48(11):6032-6052. PubMed ID: 32427332
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.