BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

582 related articles for article (PubMed ID: 34481338)

  • 1. Further SAR studies on natural template based neuroprotective molecules for the treatment of Alzheimer's disease.
    Singh YP; Shankar G; Jahan S; Singh G; Kumar N; Barik A; Upadhyay P; Singh L; Kamble K; Singh GK; Tiwari S; Garg P; Gupta S; Modi G
    Bioorg Med Chem; 2021 Sep; 46():116385. PubMed ID: 34481338
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Amiridine-piperazine hybrids as cholinesterase inhibitors and potential multitarget agents for Alzheimer's disease treatment.
    Makhaeva GF; Lushchekina SV; Kovaleva NV; Yu Astakhova T; Boltneva NP; Rudakova EV; Serebryakova OG; Proshin AN; Serkov IV; Trofimova TP; Tafeenko VA; Radchenko EV; Palyulin VA; Fisenko VP; Korábečný J; Soukup O; Richardson RJ
    Bioorg Chem; 2021 Jul; 112():104974. PubMed ID: 34029971
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Design, synthesis and biological evaluation of novel naturally-inspired multifunctional molecules for the management of Alzheimer's disease.
    Singh YP; Tej GNVC; Pandey A; Priya K; Pandey P; Shankar G; Nayak PK; Rai G; Chittiboyina AG; Doerksen RJ; Vishwakarma S; Modi G
    Eur J Med Chem; 2020 Jul; 198():112257. PubMed ID: 32375073
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Design, synthesis, and biological evaluation of ferulic acid based 1,3,4-oxadiazole hybrids as multifunctional therapeutics for the treatment of Alzheimer's disease.
    Tripathi A; Choubey PK; Sharma P; Seth A; Saraf P; Shrivastava SK
    Bioorg Chem; 2020 Jan; 95():103506. PubMed ID: 31887472
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Design, synthesis, and biological evaluation of novel xanthone-alkylbenzylamine hybrids as multifunctional agents for the treatment of Alzheimer's disease.
    Zhang Z; Guo J; Cheng M; Zhou W; Wan Y; Wang R; Fang Y; Jin Y; Liu J; Xie SS
    Eur J Med Chem; 2021 Mar; 213():113154. PubMed ID: 33476932
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis and Biological Activity of Some Benzochromenoquinolinones: Tacrine Analogs as Potent Anti-Alzheimer's Agents.
    Mahdavi M; Hariri R; Mirfazli SS; Lotfian H; Rastergari A; Firuzi O; Edraki N; Larijani B; Akbarzadeh T; Saeedi M
    Chem Biodivers; 2019 Apr; 16(4):e1800488. PubMed ID: 30720917
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Bis-Amiridines as Acetylcholinesterase and Butyrylcholinesterase Inhibitors:
    Makhaeva GF; Kovaleva NV; Boltneva NP; Rudakova EV; Lushchekina SV; Astakhova TY; Serkov IV; Proshin AN; Radchenko EV; Palyulin VA; Korabecny J; Soukup O; Bachurin SO; Richardson RJ
    Molecules; 2022 Feb; 27(3):. PubMed ID: 35164325
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Interest of novel N-alkylpyridinium-indolizine hybrids in the field of Alzheimer's disease: Synthesis, characterization and evaluation of antioxidant activity, cholinesterase inhibition, and amyloid fibrillation interference.
    Baussanne I; Firstova O; Dediu AB; Larosa C; Furdui B; Ghinea IO; Thomas A; Chierici S; Dinica R; Demeunynck M
    Bioorg Chem; 2021 Nov; 116():105390. PubMed ID: 34670332
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Conjugates of tacrine and 1,2,4-thiadiazole derivatives as new potential multifunctional agents for Alzheimer's disease treatment: Synthesis, quantum-chemical characterization, molecular docking, and biological evaluation.
    Makhaeva GF; Kovaleva NV; Boltneva NP; Lushchekina SV; Rudakova EV; Stupina TS; Terentiev AA; Serkov IV; Proshin AN; Radchenko EV; Palyulin VA; Bachurin SO; Richardson RJ
    Bioorg Chem; 2020 Jan; 94():103387. PubMed ID: 31735356
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis and in vitro evaluation of vanillin derivatives as multi-target therapeutics for the treatment of Alzheimer's disease.
    Blaikie L; Kay G; Kong Thoo Lin P
    Bioorg Med Chem Lett; 2020 Nov; 30(21):127505. PubMed ID: 32822761
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Design, synthesis, biological evaluation, and molecular modeling studies of quinoline-ferulic acid hybrids as cholinesterase inhibitors.
    Mo J; Yang H; Chen T; Li Q; Lin H; Feng F; Liu W; Qu W; Guo Q; Chi H; Chen Y; Sun H
    Bioorg Chem; 2019 Dec; 93():103310. PubMed ID: 31586704
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Design, synthesis, and biological evaluation of novel (4-(1,2,4-oxadiazol-5-yl)phenyl)-2-aminoacetamide derivatives as multifunctional agents for the treatment of Alzheimer's disease.
    Liu T; Chen S; Du J; Xing S; Li R; Li Z
    Eur J Med Chem; 2022 Jan; 227():113973. PubMed ID: 34752955
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Novel Pyridine-Containing Sultones: Structure-Activity Relationship and Biological Evaluation as Selective AChE Inhibitors for the Treatment of Alzheimer's disease.
    Zhang H; Wu C; Chen X; Zhang Z; Jiang X; Qin HL; Tang W
    ChemMedChem; 2021 Oct; 16(20):3189-3200. PubMed ID: 34036731
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis, bioactivity and molecular modeling studies on potential anti-Alzheimer piperidinehydrazide-hydrazones.
    Parlar S; Sayar G; Tarikogullari AH; Karadagli SS; Alptuzun V; Erciyas E; Holzgrabe U
    Bioorg Chem; 2019 Jun; 87():888-900. PubMed ID: 30538051
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Selective Pseudo-irreversible Butyrylcholinesterase Inhibitors Transferring Antioxidant Moieties to the Enzyme Show Pronounced Neuroprotective Efficacy In Vitro and In Vivo in an Alzheimer's Disease Mouse Model.
    Scheiner M; Hoffmann M; He F; Poeta E; Chatonnet A; Monti B; Maurice T; Decker M
    J Med Chem; 2021 Jul; 64(13):9302-9320. PubMed ID: 34152756
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Design, synthesis,
    Mo J; Chen T; Yang H; Guo Y; Li Q; Qiao Y; Lin H; Feng F; Liu W; Chen Y; Liu Z; Sun H
    J Enzyme Inhib Med Chem; 2020 Dec; 35(1):330-343. PubMed ID: 31856607
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis, pharmacological assessment, molecular modeling and in silico studies of fused tricyclic coumarin derivatives as a new family of multifunctional anti-Alzheimer agents.
    Shaik JB; Palaka BK; Penumala M; Kotapati KV; Devineni SR; Eadlapalli S; Darla MM; Ampasala DR; Vadde R; Amooru GD
    Eur J Med Chem; 2016 Jan; 107():219-32. PubMed ID: 26588065
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis, pharmacology and molecular docking on multifunctional tacrine-ferulic acid hybrids as cholinesterase inhibitors against Alzheimer's disease.
    Zhu J; Yang H; Chen Y; Lin H; Li Q; Mo J; Bian Y; Pei Y; Sun H
    J Enzyme Inhib Med Chem; 2018 Dec; 33(1):496-506. PubMed ID: 29405075
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Design, synthesis, and evaluation of novel cinnamic acid-tryptamine hybrid for inhibition of acetylcholinesterase and butyrylcholinesterase.
    Ghafary S; Ghobadian R; Mahdavi M; Nadri H; Moradi A; Akbarzadeh T; Najafi Z; Sharifzadeh M; Edraki N; Moghadam FH; Amini M
    Daru; 2020 Dec; 28(2):463-477. PubMed ID: 32372339
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Comparative Cholinesterase, α-Glucosidase Inhibitory, Antioxidant, Molecular Docking, and Kinetic Studies on Potent Succinimide Derivatives.
    Ahmad A; Ullah F; Sadiq A; Ayaz M; Saeed Jan M; Shahid M; Wadood A; Mahmood F; Rashid U; Ullah R; Sahibzada MUK; Alqahtani AS; Mahmood HM
    Drug Des Devel Ther; 2020; 14():2165-2178. PubMed ID: 32606589
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 30.