213 related articles for article (PubMed ID: 34486668)
1. Gene-teratogen interactions influence the penetrance of birth defects by altering Hedgehog signaling strength.
Kong JH; Young CB; Pusapati GV; Espinoza FH; Patel CB; Beckert F; Ho S; Patel BB; Gabriel GC; Aravind L; Bazan JF; Gunn TM; Lo CW; Rohatgi R
Development; 2021 Oct; 148(19):. PubMed ID: 34486668
[TBL] [Abstract][Full Text] [Related]
2. Cholesterol Modification of Smoothened Is Required for Hedgehog Signaling.
Xiao X; Tang JJ; Peng C; Wang Y; Fu L; Qiu ZP; Xiong Y; Yang LF; Cui HW; He XL; Yin L; Qi W; Wong CC; Zhao Y; Li BL; Qiu WW; Song BL
Mol Cell; 2017 Apr; 66(1):154-162.e10. PubMed ID: 28344083
[TBL] [Abstract][Full Text] [Related]
3. A Membrane-Tethered Ubiquitination Pathway Regulates Hedgehog Signaling and Heart Development.
Kong JH; Young CB; Pusapati GV; Patel CB; Ho S; Krishnan A; Lin JI; Devine W; Moreau de Bellaing A; Athni TS; Aravind L; Gunn TM; Lo CW; Rohatgi R
Dev Cell; 2020 Nov; 55(4):432-449.e12. PubMed ID: 32966817
[TBL] [Abstract][Full Text] [Related]
4. G protein-coupled receptors control the sensitivity of cells to the morphogen Sonic Hedgehog.
Pusapati GV; Kong JH; Patel BB; Gouti M; Sagner A; Sircar R; Luchetti G; Ingham PW; Briscoe J; Rohatgi R
Sci Signal; 2018 Feb; 11(516):. PubMed ID: 29438014
[TBL] [Abstract][Full Text] [Related]
5. Regulation of Smoothened Phosphorylation and High-Level Hedgehog Signaling Activity by a Plasma Membrane Associated Kinase.
Li S; Li S; Han Y; Tong C; Wang B; Chen Y; Jiang J
PLoS Biol; 2016 Jun; 14(6):e1002481. PubMed ID: 27280464
[TBL] [Abstract][Full Text] [Related]
6. DYRK1B as therapeutic target in Hedgehog/GLI-dependent cancer cells with Smoothened inhibitor resistance.
Gruber W; Hutzinger M; Elmer DP; Parigger T; Sternberg C; Cegielkowski L; Zaja M; Leban J; Michel S; Hamm S; Vitt D; Aberger F
Oncotarget; 2016 Feb; 7(6):7134-48. PubMed ID: 26784250
[TBL] [Abstract][Full Text] [Related]
7. Δ9-Tetrahydrocannabinol inhibits Hedgehog-dependent patterning during development.
Lo HF; Hong M; Szutorisz H; Hurd YL; Krauss RS
Development; 2021 Oct; 148(19):. PubMed ID: 34610637
[TBL] [Abstract][Full Text] [Related]
8. Structures of vertebrate Patched and Smoothened reveal intimate links between cholesterol and Hedgehog signalling.
Kowatsch C; Woolley RE; Kinnebrew M; Rohatgi R; Siebold C
Curr Opin Struct Biol; 2019 Aug; 57():204-214. PubMed ID: 31247512
[TBL] [Abstract][Full Text] [Related]
9. CRISPR Screens Uncover Genes that Regulate Target Cell Sensitivity to the Morphogen Sonic Hedgehog.
Pusapati GV; Kong JH; Patel BB; Krishnan A; Sagner A; Kinnebrew M; Briscoe J; Aravind L; Rohatgi R
Dev Cell; 2018 Jan; 44(1):113-129.e8. PubMed ID: 29290584
[TBL] [Abstract][Full Text] [Related]
10.
Hong M; Christ A; Christa A; Willnow TE; Krauss RS
Elife; 2020 Sep; 9():. PubMed ID: 32876567
[TBL] [Abstract][Full Text] [Related]
11. Inhibition of Hedgehog-dependent tumors and cancer stem cells by a newly identified naturally occurring chemotype.
Infante P; Alfonsi R; Ingallina C; Quaglio D; Ghirga F; D'Acquarica I; Bernardi F; Di Magno L; Canettieri G; Screpanti I; Gulino A; Botta B; Mori M; Di Marcotullio L
Cell Death Dis; 2016 Sep; 7(9):e2376. PubMed ID: 27899820
[TBL] [Abstract][Full Text] [Related]
12. Mechanisms of Smoothened Regulation in Hedgehog Signaling.
Zhang J; Liu Z; Jia J
Cells; 2021 Aug; 10(8):. PubMed ID: 34440907
[TBL] [Abstract][Full Text] [Related]
13. Sonic Hedgehog Activates Phospholipase A2 to Enhance Smoothened Ciliary Translocation.
Arensdorf AM; Dillard ME; Menke JM; Frank MW; Rock CO; Ogden SK
Cell Rep; 2017 Jun; 19(10):2074-2087. PubMed ID: 28591579
[TBL] [Abstract][Full Text] [Related]
14. Regulation of Smoothened Trafficking and Hedgehog Signaling by the SUMO Pathway.
Ma G; Li S; Han Y; Li S; Yue T; Wang B; Jiang J
Dev Cell; 2016 Nov; 39(4):438-451. PubMed ID: 27746045
[TBL] [Abstract][Full Text] [Related]
15. Secreted tyrosine kinase Vlk negatively regulates Hedgehog signaling by inducing lysosomal degradation of Smoothened.
Kim JM; Han H; Bahn M; Hur Y; Yeo CY; Kim DW
Biochem J; 2020 Jan; 477(1):121-136. PubMed ID: 31845979
[TBL] [Abstract][Full Text] [Related]
16. Novel-smoothened inhibitors for therapeutic targeting of naïve and drug-resistant hedgehog pathway-driven cancers.
Li QR; Zhao H; Zhang XS; Lang H; Yu K
Acta Pharmacol Sin; 2019 Feb; 40(2):257-267. PubMed ID: 29777201
[TBL] [Abstract][Full Text] [Related]
17. The interplay of Patched, Smoothened and cholesterol in Hedgehog signaling.
Hu A; Song BL
Curr Opin Cell Biol; 2019 Dec; 61():31-38. PubMed ID: 31369952
[TBL] [Abstract][Full Text] [Related]
18. Impact of the Smoothened inhibitor, IPI-926, on smoothened ciliary localization and Hedgehog pathway activity.
Peluso MO; Campbell VT; Harari JA; Tibbitts TT; Proctor JL; Whitebread N; Conley JM; White KF; Kutok JL; Read MA; McGovern K; Faia KL
PLoS One; 2014; 9(3):e90534. PubMed ID: 24608250
[TBL] [Abstract][Full Text] [Related]
19. An essential function for autocrine hedgehog signaling in epithelial proliferation and differentiation in the trachea.
Yin W; Liontos A; Koepke J; Ghoul M; Mazzocchi L; Liu X; Lu C; Wu H; Fysikopoulos A; Sountoulidis A; Seeger W; Ruppert C; Günther A; Stainier DYR; Samakovlis C
Development; 2022 Feb; 149(3):. PubMed ID: 35112129
[TBL] [Abstract][Full Text] [Related]
20. Ciliary smoothened-mediated noncanonical hedgehog signaling promotes tubulin acetylation.
Lee H; Ko HW
Biochem Biophys Res Commun; 2016 Nov; 480(4):574-579. PubMed ID: 27793670
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
