231 related articles for article (PubMed ID: 34489423)
1. C9orf72-derived arginine-rich poly-dipeptides impede phase modifiers.
Nanaura H; Kawamukai H; Fujiwara A; Uehara T; Aiba Y; Nakanishi M; Shiota T; Hibino M; Wiriyasermkul P; Kikuchi S; Nagata R; Matsubayashi M; Shinkai Y; Niwa T; Mannen T; Morikawa N; Iguchi N; Kiriyama T; Morishima K; Inoue R; Sugiyama M; Oda T; Kodera N; Toma-Fukai S; Sato M; Taguchi H; Nagamori S; Shoji O; Ishimori K; Matsumura H; Sugie K; Saio T; Yoshizawa T; Mori E
Nat Commun; 2021 Sep; 12(1):5301. PubMed ID: 34489423
[TBL] [Abstract][Full Text] [Related]
2. Structural and energetic basis of ALS-causing mutations in the atypical proline-tyrosine nuclear localization signal of the Fused in Sarcoma protein (FUS).
Zhang ZC; Chook YM
Proc Natl Acad Sci U S A; 2012 Jul; 109(30):12017-21. PubMed ID: 22778397
[TBL] [Abstract][Full Text] [Related]
3. Mechanism of karyopherin-β2 binding and nuclear import of ALS variants FUS(P525L) and FUS(R495X).
Gonzalez A; Mannen T; Çağatay T; Fujiwara A; Matsumura H; Niesman AB; Brautigam CA; Chook YM; Yoshizawa T
Sci Rep; 2021 Feb; 11(1):3754. PubMed ID: 33580145
[TBL] [Abstract][Full Text] [Related]
4.
Hayes LR; Duan L; Bowen K; Kalab P; Rothstein JD
Elife; 2020 Mar; 9():. PubMed ID: 32119645
[TBL] [Abstract][Full Text] [Related]
5. R521C and R521H mutations in FUS result in weak binding with Karyopherinβ2 leading to Amyotrophic lateral sclerosis: a molecular docking and dynamics study.
Swetha RG; Ramaiah S; Anbarasu A
J Biomol Struct Dyn; 2017 Aug; 35(10):2169-2185. PubMed ID: 27381509
[TBL] [Abstract][Full Text] [Related]
6. A proline-tyrosine nuclear localization signal (PY-NLS) is required for the nuclear import of fission yeast PAB2, but not of human PABPN1.
Mallet PL; Bachand F
Traffic; 2013 Mar; 14(3):282-94. PubMed ID: 23279110
[TBL] [Abstract][Full Text] [Related]
7. A Phosphorylation-Induced Switch in the Nuclear Localization Sequence of the Intrinsically Disordered NUPR1 Hampers Binding to Importin.
Neira JL; Rizzuti B; Jiménez-Alesanco A; Palomino-Schätzlein M; Abián O; Velázquez-Campoy A; Iovanna JL
Biomolecules; 2020 Sep; 10(9):. PubMed ID: 32933064
[TBL] [Abstract][Full Text] [Related]
8. Nuclear-Import Receptors Reverse Aberrant Phase Transitions of RNA-Binding Proteins with Prion-like Domains.
Guo L; Kim HJ; Wang H; Monaghan J; Freyermuth F; Sung JC; O'Donovan K; Fare CM; Diaz Z; Singh N; Zhang ZC; Coughlin M; Sweeny EA; DeSantis ME; Jackrel ME; Rodell CB; Burdick JA; King OD; Gitler AD; Lagier-Tourenne C; Pandey UB; Chook YM; Taylor JP; Shorter J
Cell; 2018 Apr; 173(3):677-692.e20. PubMed ID: 29677512
[TBL] [Abstract][Full Text] [Related]
9. Nuclear Respiratory Factor 2β (NRF-2β) recruits NRF-2α to the nucleus by binding to importin-α:β via an unusual monopartite-type nuclear localization signal.
Hayashi R; Takeuchi N; Ueda T
J Mol Biol; 2013 Sep; 425(18):3536-48. PubMed ID: 23856623
[TBL] [Abstract][Full Text] [Related]
10. Karyopherin-β2 Recognition of a PY-NLS Variant that Lacks the Proline-Tyrosine Motif.
Soniat M; Chook YM
Structure; 2016 Oct; 24(10):1802-1809. PubMed ID: 27618664
[TBL] [Abstract][Full Text] [Related]
11. Characterization of membrane penetration and cytotoxicity of C9orf72-encoding arginine-rich dipeptides.
Kanekura K; Harada Y; Fujimoto M; Yagi T; Hayamizu Y; Nagaoka K; Kuroda M
Sci Rep; 2018 Aug; 8(1):12740. PubMed ID: 30143685
[TBL] [Abstract][Full Text] [Related]
12. A minimal construct of nuclear-import receptor Karyopherin-β2 defines the regions critical for chaperone and disaggregation activity.
Fare CM; Rhine K; Lam A; Myong S; Shorter J
J Biol Chem; 2023 Feb; 299(2):102806. PubMed ID: 36529289
[TBL] [Abstract][Full Text] [Related]
13. Molecular basis of C9orf72 poly-PR interference with the β-karyopherin family of nuclear transport receptors.
Jafarinia H; Van der Giessen E; Onck PR
Sci Rep; 2022 Dec; 12(1):21324. PubMed ID: 36494425
[TBL] [Abstract][Full Text] [Related]
14. Crystal structure of human Karyopherin β2 bound to the PY-NLS of Saccharomyces cerevisiae Nab2.
Soniat M; Sampathkumar P; Collett G; Gizzi AS; Banu RN; Bhosle RC; Chamala S; Chowdhury S; Fiser A; Glenn AS; Hammonds J; Hillerich B; Khafizov K; Love JD; Matikainen B; Seidel RD; Toro R; Rajesh Kumar P; Bonanno JB; Chook YM; Almo SC
J Struct Funct Genomics; 2013 Jun; 14(2):31-5. PubMed ID: 23535894
[TBL] [Abstract][Full Text] [Related]
15. Phase Separation of FUS Is Suppressed by Its Nuclear Import Receptor and Arginine Methylation.
Hofweber M; Hutten S; Bourgeois B; Spreitzer E; Niedner-Boblenz A; Schifferer M; Ruepp MD; Simons M; Niessing D; Madl T; Dormann D
Cell; 2018 Apr; 173(3):706-719.e13. PubMed ID: 29677514
[TBL] [Abstract][Full Text] [Related]
16. C9orf72-generated poly-GR and poly-PR do not directly interfere with nucleocytoplasmic transport.
Vanneste J; Vercruysse T; Boeynaems S; Sicart A; Van Damme P; Daelemans D; Van Den Bosch L
Sci Rep; 2019 Oct; 9(1):15728. PubMed ID: 31673013
[TBL] [Abstract][Full Text] [Related]
17. Nuclear-Import Receptors Counter Deleterious Phase Transitions in Neurodegenerative Disease.
Odeh HM; Fare CM; Shorter J
J Mol Biol; 2022 Jan; 434(1):167220. PubMed ID: 34464655
[TBL] [Abstract][Full Text] [Related]
18. The RNA-binding protein FUS is chaperoned and imported into the nucleus by a network of import receptors.
Baade I; Hutten S; Sternburg EL; Pörschke M; Hofweber M; Dormann D; Kehlenbach RH
J Biol Chem; 2021; 296():100659. PubMed ID: 33857479
[TBL] [Abstract][Full Text] [Related]
19. A bimodular nuclear localization signal assembled via an extended double-stranded RNA-binding domain acts as an RNA-sensing signal for transportin 1.
Barraud P; Banerjee S; Mohamed WI; Jantsch MF; Allain FH
Proc Natl Acad Sci U S A; 2014 May; 111(18):E1852-61. PubMed ID: 24753571
[TBL] [Abstract][Full Text] [Related]
20. Cell-to-cell transmission of C9orf72 poly-(Gly-Ala) triggers key features of ALS/FTD.
Khosravi B; LaClair KD; Riemenschneider H; Zhou Q; Frottin F; Mareljic N; Czuppa M; Farny D; Hartmann H; Michaelsen M; Arzberger T; Hartl FU; Hipp MS; Edbauer D
EMBO J; 2020 Apr; 39(8):e102811. PubMed ID: 32175624
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]