These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
49 related articles for article (PubMed ID: 3449092)
21. High-affinity inhibitors of dihydrofolate reductase: antimicrobial and anticancer activities of 7,8-dialkyl-1,3-diaminopyrrolo[3,2-f]quinazolines with small molecular size. Kuyper LF; Baccanari DP; Jones ML; Hunter RN; Tansik RL; Joyner SS; Boytos CM; Rudolph SK; Knick V; Wilson HR; Caddell JM; Friedman HS; Comley JC; Stables JN J Med Chem; 1996 Feb; 39(4):892-903. PubMed ID: 8632413 [TBL] [Abstract][Full Text] [Related]
22. Molecular structure and conformational composition of 2-chloro-1-phenylethanone, ClH2C-C(=O)Ph, obtained using gas-phase electron-diffraction data and results from theoretical calculations. Aarset K; Hagen K J Phys Chem A; 2005 Mar; 109(9):1897-902. PubMed ID: 16833522 [TBL] [Abstract][Full Text] [Related]
23. Conformations of beta-amino acid residues in peptides: X-ray diffraction studies of peptides containing the achiral residue 1-aminocyclohexaneacetic acid, beta3,3Ac6c. Vasudev PG; Rai R; Shamala N; Balaram P Biopolymers; 2008; 90(2):138-50. PubMed ID: 18273891 [TBL] [Abstract][Full Text] [Related]
24. Crystallographic and molecular-orbital studies on the geometry of antifolate drugs. Hunt WE; Schwalbe CH; Bird K; Mallinson PD Biochem J; 1980 May; 187(2):533-6. PubMed ID: 6893149 [TBL] [Abstract][Full Text] [Related]
25. A 2.13 A structure of E. coli dihydrofolate reductase bound to a novel competitive inhibitor reveals a new binding surface involving the M20 loop region. Summerfield RL; Daigle DM; Mayer S; Mallik D; Hughes DW; Jackson SG; Sulek M; Organ MG; Brown ED; Junop MS J Med Chem; 2006 Nov; 49(24):6977-86. PubMed ID: 17125251 [TBL] [Abstract][Full Text] [Related]
26. 2D copper(II) complex built from N-methyl-1,3-diamino-2-propanolate and azide ligands: structure, magnetic, and DFT studies. El Fallah MS; Vicente R; Tercero J; Elpelt C; Rentschler E; Solans X; Font-Bardia M Inorg Chem; 2008 Jul; 47(14):6322-8. PubMed ID: 18570412 [TBL] [Abstract][Full Text] [Related]
27. Structural studies on bio-active compounds. Part XV. Structure-activity relationships for pyrimethamine and a series of diaminopyrimidine analogues versus bacterial dihydrofolate reductase. Sansom CE; Schwalbe CH; Lambert PA; Griffin RJ; Stevens MF Biochim Biophys Acta; 1989 Mar; 995(1):21-7. PubMed ID: 2647153 [TBL] [Abstract][Full Text] [Related]
28. Copper(II) complexes of a series of alkoxy diazine ligands: mononuclear, dinuclear, and tetranuclear examples with structural, magnetic, and DFT studies. Grove H; Kelly TL; Thompson LK; Zhao L; Xu Z; Abedin TS; Miller DO; Goeta AE; Wilson C; Howard JA Inorg Chem; 2004 Jul; 43(14):4278-88. PubMed ID: 15236541 [TBL] [Abstract][Full Text] [Related]
29. Crystal structure of quinespar, a quinazoline analogue of methotrexate. Mastropaolo D; Smith HW; Camerman A; Camerman N J Med Chem; 1986 Jan; 29(1):155-8. PubMed ID: 3941409 [TBL] [Abstract][Full Text] [Related]
30. Structural and conformational properties of (Z)-beta-(1-naphthyl)- dehydroalanine residue. Inai Y; Oshikawa T; Yamashita M; Hirabayashi T; Hirako T Biopolymers; 2001 Jan; 58(1):9-19. PubMed ID: 11072225 [TBL] [Abstract][Full Text] [Related]
31. NMR solution structure of the antitumor compound PT523 and NADPH in the ternary complex with human dihydrofolate reductase. Johnson JM; Meiering EM; Wright JE; Pardo J; Rosowsky A; Wagner G Biochemistry; 1997 Apr; 36(15):4399-411. PubMed ID: 9109647 [TBL] [Abstract][Full Text] [Related]
32. Molecular structure, conformation, and potential to internal rotation of 2,6- and 3,5-difluoronitrobenzene studied by gas-phase electron diffraction and quantum chemical calculations. Dorofeeva OV; Ferenets AV; Karasev NM; Vilkov LV; Oberhammer H J Phys Chem A; 2008 Jun; 112(22):5002-9. PubMed ID: 18461918 [TBL] [Abstract][Full Text] [Related]
33. Synthesis, structural characterization, and biological studies of new antimony(III) complexes with thiones. The influence of the solvent on the geometry of the complexes. Ozturk II; Hadjikakou SK; Hadjiliadis N; Kourkoumelis N; Kubicki M; Baril M; Butler IS; Balzarini J Inorg Chem; 2007 Oct; 46(21):8652-61. PubMed ID: 17850141 [TBL] [Abstract][Full Text] [Related]
34. Dihydrofolate reductase binding and cellular uptake of nonpolyglutamatable antifolates: correlates of cytotoxicity toward methotrexate-sensitive and -resistant human head and neck squamous carcinoma cells. Chen G; Wright JE; Rosowsky A Mol Pharmacol; 1995 Oct; 48(4):758-65. PubMed ID: 7476904 [TBL] [Abstract][Full Text] [Related]
35. Study of the thymine molecule: equilibrium structure from joint analysis of gas-phase electron diffraction and microwave data and assignment of vibrational spectra using results of ab initio calculations. Vogt N; Khaikin LS; Grikina OE; Rykov AN; Vogt J J Phys Chem A; 2008 Aug; 112(33):7662-70. PubMed ID: 18665577 [TBL] [Abstract][Full Text] [Related]
36. Inhibition of dihydrofolate reductase: structure-activity correlations of quinazolines based upon molecular shape analysis. Battershell C; Malhotra D; Hopfinger AJ J Med Chem; 1981 Jul; 24(7):812-8. PubMed ID: 7277385 [TBL] [Abstract][Full Text] [Related]
37. Molecular structures of 2,4-diaminopyrimidine antifolates with antineoplastic activity. Cody V; Zakrzewski SF J Med Chem; 1982 Apr; 25(4):427-30. PubMed ID: 7069721 [TBL] [Abstract][Full Text] [Related]
38. Quantitative structure-activity relationship by distance geometry: quinazolines as dihydrofolate reductase inhibitors. Ghose AK; Crippen GM J Med Chem; 1982 Aug; 25(8):892-9. PubMed ID: 7120278 [TBL] [Abstract][Full Text] [Related]
39. Structural studies on bio-active compounds. Part 9. 2,4-Diamino-6-azidoquinazoline hydrochloride. Schwalbe CH; King ME; Wong KP; Lambert PA; Bliss A; Stevens MF Anticancer Drug Des; 1987 Dec; 2(3):289-96. PubMed ID: 3449092 [TBL] [Abstract][Full Text] [Related]
40. Analysis of quinazoline and pyrido[2,3-d]pyrimidine N9-C10 reversed-bridge antifolates in complex with NADP+ and Pneumocystis carinii dihydrofolate reductase. Cody V; Galitsky N; Luft JR; Pangborn W; Queener SF; Gangjee A Acta Crystallogr D Biol Crystallogr; 2002 Sep; 58(Pt 9):1393-9. PubMed ID: 12198294 [TBL] [Abstract][Full Text] [Related] [Previous] [Next] [New Search]