280 related articles for article (PubMed ID: 34493732)
1. Targeting the IRE1α/XBP1s pathway suppresses CARM1-expressing ovarian cancer.
Lin J; Liu H; Fukumoto T; Zundell J; Yan Q; Tang CA; Wu S; Zhou W; Guo D; Karakashev S; Hu CA; Sarma K; Kossenkov AV; Zhang R
Nat Commun; 2021 Sep; 12(1):5321. PubMed ID: 34493732
[TBL] [Abstract][Full Text] [Related]
2. Targeting the IRE1α/XBP1 Endoplasmic Reticulum Stress Response Pathway in
Zundell JA; Fukumoto T; Lin J; Fatkhudinov N; Nacarelli T; Kossenkov AV; Liu Q; Cassel J; Hu CA; Wu S; Zhang R
Cancer Res; 2021 Oct; 81(20):5325-5335. PubMed ID: 34548333
[TBL] [Abstract][Full Text] [Related]
3. IRE1α Disruption in Triple-Negative Breast Cancer Cooperates with Antiangiogenic Therapy by Reversing ER Stress Adaptation and Remodeling the Tumor Microenvironment.
Harnoss JM; Le Thomas A; Reichelt M; Guttman O; Wu TD; Marsters SA; Shemorry A; Lawrence DA; Kan D; Segal E; Merchant M; Totpal K; Crocker LM; Mesh K; Dohse M; Solon M; Modrusan Z; Rudolph J; Koeppen H; Walter P; Ashkenazi A
Cancer Res; 2020 Jun; 80(11):2368-2379. PubMed ID: 32265225
[TBL] [Abstract][Full Text] [Related]
4. IRE1α Activation in Bone Marrow-Derived Dendritic Cells Modulates Innate Recognition of Melanoma Cells and Favors CD8
Medel B; Costoya C; Fernandez D; Pereda C; Lladser A; Sauma D; Pacheco R; Iwawaki T; Salazar-Onfray F; Osorio F
Front Immunol; 2018; 9():3050. PubMed ID: 30687308
[TBL] [Abstract][Full Text] [Related]
5. IRE1α-XBP1s pathway promotes prostate cancer by activating c-MYC signaling.
Sheng X; Nenseth HZ; Qu S; Kuzu OF; Frahnow T; Simon L; Greene S; Zeng Q; Fazli L; Rennie PS; Mills IG; Danielsen H; Theis F; Patterson JB; Jin Y; Saatcioglu F
Nat Commun; 2019 Jan; 10(1):323. PubMed ID: 30679434
[TBL] [Abstract][Full Text] [Related]
6. Disruption of IRE1α through its kinase domain attenuates multiple myeloma.
Harnoss JM; Le Thomas A; Shemorry A; Marsters SA; Lawrence DA; Lu M; Chen YA; Qing J; Totpal K; Kan D; Segal E; Merchant M; Reichelt M; Ackerly Wallweber H; Wang W; Clark K; Kaufman S; Beresini MH; Laing ST; Sandoval W; Lorenzo M; Wu J; Ly J; De Bruyn T; Heidersbach A; Haley B; Gogineni A; Weimer RM; Lee D; Braun MG; Rudolph J; VanWyngarden MJ; Sherbenou DW; Gomez-Bougie P; Amiot M; Acosta-Alvear D; Walter P; Ashkenazi A
Proc Natl Acad Sci U S A; 2019 Aug; 116(33):16420-16429. PubMed ID: 31371506
[TBL] [Abstract][Full Text] [Related]
7. Triazoloacridone C-1305 impairs XBP1 splicing by acting as a potential IRE1α endoribonuclease inhibitor.
Bartoszewska S; Króliczewski J; Crossman DK; Pogorzelska A; Bagiński M; Collawn JF; Bartoszewski R
Cell Mol Biol Lett; 2021 Mar; 26(1):11. PubMed ID: 33730996
[TBL] [Abstract][Full Text] [Related]
8. Mechanism of the induction of endoplasmic reticulum stress by the anti-cancer agent, di-2-pyridylketone 4,4-dimethyl-3-thiosemicarbazone (Dp44mT): Activation of PERK/eIF2α, IRE1α, ATF6 and calmodulin kinase.
Merlot AM; Shafie NH; Yu Y; Richardson V; Jansson PJ; Sahni S; Lane DJR; Kovacevic Z; Kalinowski DS; Richardson DR
Biochem Pharmacol; 2016 Jun; 109():27-47. PubMed ID: 27059255
[TBL] [Abstract][Full Text] [Related]
9. CaMKII orchestrates endoplasmic reticulum stress and apoptosis in doxorubicin-induced cardiotoxicity by regulating the IRE1α/XBP1s pathway.
Kong L; Zhang Y; Ning J; Xu C; Wang Z; Yang J; Yang L
J Cell Mol Med; 2022 Oct; 26(20):5303-5314. PubMed ID: 36111515
[TBL] [Abstract][Full Text] [Related]
10. Arsenite Induces Vascular Endothelial Cell Dysfunction by Activating IRE1α/XBP1s/HIF1α-Dependent ANGII Signaling.
Xu X; Liu S; Aodengqimuge ; Wang H; Hu M; Xing C; Song L
Toxicol Sci; 2017 Dec; 160(2):315-328. PubMed ID: 28973481
[TBL] [Abstract][Full Text] [Related]
11. CARM1-expressing ovarian cancer depends on the histone methyltransferase EZH2 activity.
Karakashev S; Zhu H; Wu S; Yokoyama Y; Bitler BG; Park PH; Lee JH; Kossenkov AV; Gaonkar KS; Yan H; Drapkin R; Conejo-Garcia JR; Speicher DW; Ordog T; Zhang R
Nat Commun; 2018 Feb; 9(1):631. PubMed ID: 29434212
[TBL] [Abstract][Full Text] [Related]
12. IRE1α dissociates with BiP and inhibits ER stress-mediated apoptosis in cartilage development.
Han X; Zhou J; Zhang P; Song F; Jiang R; Li M; Xia F; Guo FJ
Cell Signal; 2013 Nov; 25(11):2136-46. PubMed ID: 23816533
[TBL] [Abstract][Full Text] [Related]
13. ATF6 upregulates XBP1S and inhibits ER stress-mediated apoptosis in osteoarthritis cartilage.
Guo FJ; Xiong Z; Lu X; Ye M; Han X; Jiang R
Cell Signal; 2014 Feb; 26(2):332-42. PubMed ID: 24269637
[TBL] [Abstract][Full Text] [Related]
14. XBP1S Regulates MUC5B in a Promoter Variant-Dependent Pathway in Idiopathic Pulmonary Fibrosis Airway Epithelia.
Chen G; Ribeiro CMP; Sun L; Okuda K; Kato T; Gilmore RC; Martino MB; Dang H; Abzhanova A; Lin JM; Hull-Ryde EA; Volmer AS; Randell SH; Livraghi-Butrico A; Deng Y; Scherer PE; Stripp BR; O'Neal WK; Boucher RC
Am J Respir Crit Care Med; 2019 Jul; 200(2):220-234. PubMed ID: 30973754
[No Abstract] [Full Text] [Related]
15. XBP1s acts as a transcription factor of IRE1α and promotes proliferation of colon cancer cells.
Liu S; Gao Q; Li Y; Lun J; Yu M; Zhang H; Fang J
Arch Biochem Biophys; 2023 Mar; 737():109552. PubMed ID: 36828260
[TBL] [Abstract][Full Text] [Related]
16. Inhibition of Human Dendritic Cell ER Stress Response Reduces T Cell Alloreactivity Yet Spares Donor Anti-tumor Immunity.
Betts BC; Locke FL; Sagatys EM; Pidala J; Walton K; Menges M; Reff J; Saha A; Djeu JY; Kiluk JV; Lee MC; Kim J; Kang CW; Tang CH; Frieling J; Lynch CC; List A; Rodriguez PC; Blazar BR; Conejo-Garcia JR; Del Valle JR; Hu CC; Anasetti C
Front Immunol; 2018; 9():2887. PubMed ID: 30574153
[TBL] [Abstract][Full Text] [Related]
17. Blockade of XBP1 splicing by inhibition of IRE1α is a promising therapeutic option in multiple myeloma.
Mimura N; Fulciniti M; Gorgun G; Tai YT; Cirstea D; Santo L; Hu Y; Fabre C; Minami J; Ohguchi H; Kiziltepe T; Ikeda H; Kawano Y; French M; Blumenthal M; Tam V; Kertesz NL; Malyankar UM; Hokenson M; Pham T; Zeng Q; Patterson JB; Richardson PG; Munshi NC; Anderson KC
Blood; 2012 Jun; 119(24):5772-81. PubMed ID: 22538852
[TBL] [Abstract][Full Text] [Related]
18. IRE1α-XBP1 pathway promotes melanoma progression by regulating IL-6/STAT3 signaling.
Chen C; Zhang X
J Transl Med; 2017 Feb; 15(1):42. PubMed ID: 28222747
[TBL] [Abstract][Full Text] [Related]
19. Impairment of both IRE1 expression and XBP1 activation is a hallmark of GCB DLBCL and contributes to tumor growth.
Bujisic B; De Gassart A; Tallant R; Demaria O; Zaffalon L; Chelbi S; Gilliet M; Bertoni F; Martinon F
Blood; 2017 Apr; 129(17):2420-2428. PubMed ID: 28167662
[TBL] [Abstract][Full Text] [Related]
20. Farnesoid X receptor signaling activates the hepatic X-box binding protein 1 pathway in vitro and in mice.
Liu X; Guo GL; Kong B; Hilburn DB; Hubchak SC; Park S; LeCuyer B; Hsieh A; Wang L; Fang D; Green RM
Hepatology; 2018 Jul; 68(1):304-316. PubMed ID: 29377207
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]