BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

154 related articles for article (PubMed ID: 34496234)

  • 1. SCIMP is a spatiotemporal transmembrane scaffold for Erk1/2 to direct pro-inflammatory signaling in TLR-activated macrophages.
    Lucas RM; Liu L; Curson JEB; Koh YWH; Tuladhar N; Condon ND; Das Gupta K; Burgener SS; Schroder K; Ingley E; Sweet MJ; Stow JL; Luo L
    Cell Rep; 2021 Sep; 36(10):109662. PubMed ID: 34496234
    [TBL] [Abstract][Full Text] [Related]  

  • 2. SCIMP is a universal Toll-like receptor adaptor in macrophages.
    Luo L; Curson JEB; Liu L; Wall AA; Tuladhar N; Lucas RM; Sweet MJ; Stow JL
    J Leukoc Biol; 2020 Feb; 107(2):251-262. PubMed ID: 31468585
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The transmembrane adapter SCIMP recruits tyrosine kinase Syk to phosphorylate Toll-like receptors to mediate selective inflammatory outputs.
    Liu L; Lucas RM; Nanson JD; Li Y; Whitfield J; Curson JEB; Tuladhar N; Alexandrov K; Mobli M; Sweet MJ; Kobe B; Stow JL; Luo L
    J Biol Chem; 2022 May; 298(5):101857. PubMed ID: 35337798
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Development of SH2 probes and pull-down assays to detect pathogen-induced, site-specific tyrosine phosphorylation of the TLR adaptor SCIMP.
    Luo L; Tong SJ; Wall AA; Khromykh T; Sweet MJ; Stow JL
    Immunol Cell Biol; 2017 Jul; 95(6):564-570. PubMed ID: 28290451
    [TBL] [Abstract][Full Text] [Related]  

  • 5. SCIMP is a transmembrane non-TIR TLR adaptor that promotes proinflammatory cytokine production from macrophages.
    Luo L; Bokil NJ; Wall AA; Kapetanovic R; Lansdaal NM; Marceline F; Burgess BJ; Tong SJ; Guo Z; Alexandrov K; Ross IL; Hibbs ML; Stow JL; Sweet MJ
    Nat Commun; 2017 Jan; 8():14133. PubMed ID: 28098138
    [TBL] [Abstract][Full Text] [Related]  

  • 6. An alternative downstream translation start site in the non-TIR adaptor Scimp enables selective amplification of CpG DNA responses in mouse macrophages.
    Curson JE; Luo L; Liu L; Burgess BJ; Bokil NJ; Wall AA; Brdicka T; Kapetanovic R; Stow JL; Sweet MJ
    Immunol Cell Biol; 2022 Apr; 100(4):267-284. PubMed ID: 35201640
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Ligand-regulated chimeric receptor approach reveals distinctive subcellular localization and signaling properties of the Toll-like receptors.
    Nishiya T; DeFranco AL
    J Biol Chem; 2004 Apr; 279(18):19008-17. PubMed ID: 14976215
    [TBL] [Abstract][Full Text] [Related]  

  • 8. TPL-2 Inhibits IFN-β Expression via an ERK1/2-TCF-FOS Axis in TLR4-Stimulated Macrophages.
    Blair L; Pattison MJ; Chakravarty P; Papoutsopoulou S; Bakiri L; Wagner EF; Smale S; Ley SC
    J Immunol; 2022 Feb; 208(4):941-954. PubMed ID: 35082159
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Moraxella catarrhalis activates murine macrophages through multiple toll like receptors and has reduced clearance in lungs from TLR4 mutant mice.
    Hassan F; Ren D; Zhang W; Merkel TJ; Gu XX
    PLoS One; 2012; 7(5):e37610. PubMed ID: 22662179
    [TBL] [Abstract][Full Text] [Related]  

  • 10. p38γ and p38δ kinases regulate the Toll-like receptor 4 (TLR4)-induced cytokine production by controlling ERK1/2 protein kinase pathway activation.
    Risco A; del Fresno C; Mambol A; Alsina-Beauchamp D; MacKenzie KF; Yang HT; Barber DF; Morcelle C; Arthur JS; Ley SC; Ardavin C; Cuenda A
    Proc Natl Acad Sci U S A; 2012 Jul; 109(28):11200-5. PubMed ID: 22733747
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The Transmembrane Adaptor Protein SCIMP Facilitates Sustained Dectin-1 Signaling in Dendritic Cells.
    Kralova J; Fabisik M; Pokorna J; Skopcova T; Malissen B; Brdicka T
    J Biol Chem; 2016 Aug; 291(32):16530-40. PubMed ID: 27288407
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Notch signal suppresses Toll-like receptor-triggered inflammatory responses in macrophages by inhibiting extracellular signal-regulated kinase 1/2-mediated nuclear factor κB activation.
    Zhang Q; Wang C; Liu Z; Liu X; Han C; Cao X; Li N
    J Biol Chem; 2012 Feb; 287(9):6208-17. PubMed ID: 22205705
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Tumor progression locus 2-dependent oxidative burst drives phosphorylation of extracellular signal-regulated kinase during TLR3 and 9 signaling.
    Kuriakose T; Rada B; Watford WT
    J Biol Chem; 2014 Dec; 289(52):36089-100. PubMed ID: 25378393
    [TBL] [Abstract][Full Text] [Related]  

  • 14. TLR4 phosphorylation at tyrosine 672 activates the ERK/c-FOS signaling module for LPS-induced cytokine responses in macrophages.
    Curson JEB; Liu L; Luo L; Muusse TW; Lucas RM; Gunther KS; Vajjhala PR; Abrol R; Jones A; Kapetanovic R; Stacey KJ; Stow JL; Sweet MJ
    Eur J Immunol; 2023 Jul; 53(7):e2250056. PubMed ID: 37058370
    [TBL] [Abstract][Full Text] [Related]  

  • 15. In vivo ethanol exposure down-regulates TLR2-, TLR4-, and TLR9-mediated macrophage inflammatory response by limiting p38 and ERK1/2 activation.
    Goral J; Kovacs EJ
    J Immunol; 2005 Jan; 174(1):456-63. PubMed ID: 15611271
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Toll-like receptor 4-dependent and -independent cytokine secretion induced by minimally oxidized low-density lipoprotein in macrophages.
    Miller YI; Viriyakosol S; Worrall DS; Boullier A; Butler S; Witztum JL
    Arterioscler Thromb Vasc Biol; 2005 Jun; 25(6):1213-9. PubMed ID: 15718493
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Signalling, sorting and scaffolding adaptors for Toll-like receptors.
    Luo L; Lucas RM; Liu L; Stow JL
    J Cell Sci; 2019 Dec; 133(5):. PubMed ID: 31889021
    [TBL] [Abstract][Full Text] [Related]  

  • 18. MARCO, TLR2, and CD14 are required for macrophage cytokine responses to mycobacterial trehalose dimycolate and Mycobacterium tuberculosis.
    Bowdish DM; Sakamoto K; Kim MJ; Kroos M; Mukhopadhyay S; Leifer CA; Tryggvason K; Gordon S; Russell DG
    PLoS Pathog; 2009 Jun; 5(6):e1000474. PubMed ID: 19521507
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Anti-inflammatory actions of Syk inhibitors in macrophages involve non-specific inhibition of toll-like receptors-mediated JNK signaling pathway.
    Lin YC; Huang DY; Chu CL; Lin WW
    Mol Immunol; 2010 Apr; 47(7-8):1569-78. PubMed ID: 20138367
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mutant Huntingtin affects toll-like receptor 4 intracellular trafficking and cytokine production in mast cells.
    Pérez-Rodríguez MJ; Ibarra-Sánchez A; Román-Figueroa A; Pérez-Severiano F; González-Espinosa C
    J Neuroinflammation; 2020 Mar; 17(1):95. PubMed ID: 32220257
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.