BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

320 related articles for article (PubMed ID: 34500796)

  • 1. Sensitization to Drug Treatment in Precursor B-Cell Acute Lymphoblastic Leukemia Is Not Achieved by Stromal NF-κB Inhibition of Cell Adhesion but by Stromal PKC-Dependent Inhibition of ABC Transporters Activity.
    Ruiz-Aparicio PF; Uribe GI; Linares-Ballesteros A; Vernot JP
    Molecules; 2021 Sep; 26(17):. PubMed ID: 34500796
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Dual Targeting of Stromal Cell Support and Leukemic Cell Growth by a Peptidic PKC Inhibitor Shows Effectiveness against B-ALL.
    Ruiz-Aparicio PF; Vanegas NP; Uribe GI; Ortiz-Montero P; Cadavid-Cortés C; Lagos J; Flechas-Afanador J; Linares-Ballesteros A; Vernot JP
    Int J Mol Sci; 2020 May; 21(10):. PubMed ID: 32466311
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Simultaneously Targeting Two Coupled Signalling Molecules in the Mesenchymal Stem Cell Support Efficiently Sensitises the Multiple Myeloma Cell Line H929 to Bortezomib.
    Rojas-Zambrano PM; Meyer-Herrera JE; Ruiz-Aparicio PF; Vernot JP
    Int J Mol Sci; 2023 May; 24(9):. PubMed ID: 37175864
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Overcoming Microenvironment-Mediated Chemoprotection through Stromal Galectin-3 Inhibition in Acute Lymphoblastic Leukemia.
    Tarighat SS; Fei F; Joo EJ; Abdel-Azim H; Yang L; Geng H; Bum-Erdene K; Grice ID; von Itzstein M; Blanchard H; Heisterkamp N
    Int J Mol Sci; 2021 Nov; 22(22):. PubMed ID: 34830047
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The protein kinase C inhibitor enzastaurin exhibits antitumor activity against uveal melanoma.
    Wu X; Zhu M; Fletcher JA; Giobbie-Hurder A; Hodi FS
    PLoS One; 2012; 7(1):e29622. PubMed ID: 22253748
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Protein kinase C inhibitor AEB071 targets ocular melanoma harboring GNAQ mutations via effects on the PKC/Erk1/2 and PKC/NF-κB pathways.
    Wu X; Li J; Zhu M; Fletcher JA; Hodi FS
    Mol Cancer Ther; 2012 Sep; 11(9):1905-14. PubMed ID: 22653968
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Bone marrow stroma-induced resistance of chronic lymphocytic leukemia cells to arsenic trioxide involves Mcl-1 upregulation and is overcome by inhibiting the PI3Kδ or PKCβ signaling pathways.
    Amigo-Jiménez I; Bailón E; Aguilera-Montilla N; Terol MJ; García-Marco JA; García-Pardo A
    Oncotarget; 2015 Dec; 6(42):44832-48. PubMed ID: 26540567
    [TBL] [Abstract][Full Text] [Related]  

  • 8. B-cell precursor acute lymphoblastic leukemia and stromal cells communicate through Galectin-3.
    Fei F; Joo EJ; Tarighat SS; Schiffer I; Paz H; Fabbri M; Abdel-Azim H; Groffen J; Heisterkamp N
    Oncotarget; 2015 May; 6(13):11378-94. PubMed ID: 25869099
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Paclitaxel-induced immune suppression is associated with NF-kappaB activation via conventional PKC isotypes in lipopolysaccharide-stimulated 70Z/3 pre-B lymphocyte tumor cells.
    Lee M; Jeon YJ
    Mol Pharmacol; 2001 Feb; 59(2):248-53. PubMed ID: 11160860
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The Expression and Activation of the NF-κB Pathway Correlate with Methotrexate Resistance and Cell Proliferation in Acute Lymphoblastic Leukemia.
    Canevarolo RR; Cury NM; Yunes JA
    Genes (Basel); 2023 Sep; 14(10):. PubMed ID: 37895229
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Suppression of B-cell development genes is key to glucocorticoid efficacy in treatment of acute lymphoblastic leukemia.
    Kruth KA; Fang M; Shelton DN; Abu-Halawa O; Mahling R; Yang H; Weissman JS; Loh ML; Müschen M; Tasian SK; Bassik MC; Kampmann M; Pufall MA
    Blood; 2017 Jun; 129(22):3000-3008. PubMed ID: 28424165
    [TBL] [Abstract][Full Text] [Related]  

  • 12. NF-κB and AKT signaling prevent DNA damage in transformed pre-B cells by suppressing RAG1/2 expression and activity.
    Ochodnicka-Mackovicova K; Bahjat M; Bloedjes TA; Maas C; de Bruin AM; Bende RJ; van Noesel CJ; Guikema JE
    Blood; 2015 Sep; 126(11):1324-35. PubMed ID: 26153519
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Treatment of B-cell precursor acute lymphoblastic leukemia with the Galectin-1 inhibitor PTX008.
    Paz H; Joo EJ; Chou CH; Fei F; Mayo KH; Abdel-Azim H; Ghazarian H; Groffen J; Heisterkamp N
    J Exp Clin Cancer Res; 2018 Mar; 37(1):67. PubMed ID: 29580262
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Close interaction with bone marrow mesenchymal stromal cells induces the development of cancer stem cell-like immunophenotype in B cell precursor acute lymphoblastic leukemia cells.
    Kihira K; Chelakkot VS; Kainuma H; Okumura Y; Tsuboya N; Okamura S; Kurihara K; Iwamoto S; Komada Y; Hori H
    Int J Hematol; 2020 Dec; 112(6):795-806. PubMed ID: 32862292
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Compensatory IKKalpha activation of classical NF-kappaB signaling during IKKbeta inhibition identified by an RNA interference sensitization screen.
    Lam LT; Davis RE; Ngo VN; Lenz G; Wright G; Xu W; Zhao H; Yu X; Dang L; Staudt LM
    Proc Natl Acad Sci U S A; 2008 Dec; 105(52):20798-803. PubMed ID: 19104039
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Simultaneous targeting of PI3Kδ and a PI3Kδ-dependent MEK1/2-Erk1/2 pathway for therapy in pediatric B-cell acute lymphoblastic leukemia.
    Wang X; Zhang X; Li BS; Zhai X; Yang Z; Ding LX; Wang H; Liang C; Zhu W; Ding J; Meng LH
    Oncotarget; 2014 Nov; 5(21):10732-44. PubMed ID: 25313141
    [TBL] [Abstract][Full Text] [Related]  

  • 17. VS-5584 as a PI3K/mTOR inhibitor enhances apoptotic effects of subtoxic dose arsenic trioxide via inhibition of NF-κB activity in B cell precursor-acute lymphoblastic leukemia.
    Toosi B; Zaker F; Alikarami F; Kazemi A; Teremmahi Ardestanii M
    Biomed Pharmacother; 2018 Jun; 102():428-437. PubMed ID: 29574283
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Phenotypic and Functional Alterations of Hematopoietic Stem and Progenitor Cells in an In Vitro Leukemia-Induced Microenvironment.
    Vernot JP; Bonilla X; Rodriguez-Pardo V; Vanegas NP
    Int J Mol Sci; 2017 Feb; 18(2):. PubMed ID: 28216566
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Protein kinase c-β-dependent activation of NF-κB in stromal cells is indispensable for the survival of chronic lymphocytic leukemia B cells in vivo.
    Lutzny G; Kocher T; Schmidt-Supprian M; Rudelius M; Klein-Hitpass L; Finch AJ; Dürig J; Wagner M; Haferlach C; Kohlmann A; Schnittger S; Seifert M; Wanninger S; Zaborsky N; Oostendorp R; Ruland J; Leitges M; Kuhnt T; Schäfer Y; Lampl B; Peschel C; Egle A; Ringshausen I
    Cancer Cell; 2013 Jan; 23(1):77-92. PubMed ID: 23328482
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synergistic cytotoxic effects of bortezomib and CK2 inhibitor CX-4945 in acute lymphoblastic leukemia: turning off the prosurvival ER chaperone BIP/Grp78 and turning on the pro-apoptotic NF-κB.
    Buontempo F; Orsini E; Lonetti A; Cappellini A; Chiarini F; Evangelisti C; Evangelisti C; Melchionda F; Pession A; Bertaina A; Locatelli F; Bertacchini J; Neri LM; McCubrey JA; Martelli AM
    Oncotarget; 2016 Jan; 7(2):1323-40. PubMed ID: 26593250
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.