These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

213 related articles for article (PubMed ID: 34502089)

  • 1. ATG101 Degradation by HUWE1-Mediated Ubiquitination Impairs Autophagy and Reduces Survival in Cancer Cells.
    Lee J; Kim J; Shin J; Kang Y; Choi J; Cheong H
    Int J Mol Sci; 2021 Aug; 22(17):. PubMed ID: 34502089
    [TBL] [Abstract][Full Text] [Related]  

  • 2. mTORC1-Regulated and HUWE1-Mediated WIPI2 Degradation Controls Autophagy Flux.
    Wan W; You Z; Zhou L; Xu Y; Peng C; Zhou T; Yi C; Shi Y; Liu W
    Mol Cell; 2018 Oct; 72(2):303-315.e6. PubMed ID: 30340022
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A novel SNP in HUWE1 promoter confers increased risk of NOA by affecting the RA/RARα pathway in Chinese individuals.
    Shan X; Zhang X; Huang G; Lv J; Ye Z; Jiang C; Jiang X; Cheng J; Lin H; Jiang H; Yue H; Wang Z; Xu W
    Andrology; 2024 Feb; 12(2):338-348. PubMed ID: 37290064
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The C-terminal region of ATG101 bridges ULK1 and PtdIns3K complex in autophagy initiation.
    Kim BW; Jin Y; Kim J; Kim JH; Jung J; Kang S; Kim IY; Kim J; Cheong H; Song HK
    Autophagy; 2018; 14(12):2104-2116. PubMed ID: 30081750
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Suppression of autophagy during mitosis via CUL4-RING ubiquitin ligases-mediated WIPI2 polyubiquitination and proteasomal degradation.
    Lu G; Yi J; Gubas A; Wang YT; Wu Y; Ren Y; Wu M; Shi Y; Ouyang C; Tan HWS; Wang T; Wang L; Yang ND; Deng S; Xia D; Chen RH; Tooze SA; Shen HM
    Autophagy; 2019 Nov; 15(11):1917-1934. PubMed ID: 30898011
    [TBL] [Abstract][Full Text] [Related]  

  • 6. MTORC1 regulates autophagic membrane growth by targeting WIPI2.
    Wan W; Liu W
    Autophagy; 2019 Apr; 15(4):742-743. PubMed ID: 30646805
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The structure and regulation of the E3 ubiquitin ligase HUWE1 and its biological functions in cancer.
    Gong X; Du D; Deng Y; Zhou Y; Sun L; Yuan S
    Invest New Drugs; 2020 Apr; 38(2):515-524. PubMed ID: 32008177
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Quantitative Lys-ϵ-Gly-Gly (diGly) proteomics coupled with inducible RNAi reveals ubiquitin-mediated proteolysis of DNA damage-inducible transcript 4 (DDIT4) by the E3 ligase HUWE1.
    Thompson JW; Nagel J; Hoving S; Gerrits B; Bauer A; Thomas JR; Kirschner MW; Schirle M; Luchansky SJ
    J Biol Chem; 2014 Oct; 289(42):28942-55. PubMed ID: 25147182
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The E3 ubiquitin ligase HUWE1 acts through the N-Myc-DLL1-NOTCH1 signaling axis to suppress glioblastoma progression.
    Yuan Y; Wang LH; Zhao XX; Wang J; Zhang MS; Ma QH; Wei S; Yan ZX; Cheng Y; Chen XQ; Zou HB; Ge J; Wang Y; Zhang X; Cui YH; Luo T; Bian XW
    Cancer Commun (Lond); 2022 Sep; 42(9):868-886. PubMed ID: 35848447
    [TBL] [Abstract][Full Text] [Related]  

  • 10. CRL4B
    Liu F; Cao L; Zhang T; Chang F; Xu Y; Li Q; Deng J; Li L; Shao G
    Biochem Biophys Res Commun; 2018 Jun; 501(2):440-447. PubMed ID: 29738775
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Tobramycin suppresses HUWE1 degradation to control MCL-1 stability during tumour development.
    He J; Wu S; Li X; Tang L; Chen H; Qin L; Xie J; Lu T; Xu W
    Clin Exp Pharmacol Physiol; 2020 Sep; 47(9):1600-1610. PubMed ID: 32378766
    [TBL] [Abstract][Full Text] [Related]  

  • 12. LUBAC and OTULIN regulate autophagy initiation and maturation by mediating the linear ubiquitination and the stabilization of ATG13.
    Chu Y; Kang Y; Yan C; Yang C; Zhang T; Huo H; Liu Y
    Autophagy; 2021 Jul; 17(7):1684-1699. PubMed ID: 32543267
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Associations between Huwe1 and autophagy in rat cerebral neuron oxygen‑glucose deprivation and reperfusion injury.
    He GQ; Chen Y; Liao HJ; Xu WM; Zhang W; He GL
    Mol Med Rep; 2020 Dec; 22(6):5083-5094. PubMed ID: 33173969
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Solenoid architecture of HUWE1 contributes to ligase activity and substrate recognition.
    Hunkeler M; Jin CY; Ma MW; Monda JK; Overwijn D; Bennett EJ; Fischer ES
    Mol Cell; 2021 Sep; 81(17):3468-3480.e7. PubMed ID: 34314700
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Destabilization of Atoh1 by E3 Ubiquitin Ligase Huwe1 and Casein Kinase 1 Is Essential for Normal Sensory Hair Cell Development.
    Cheng YF; Tong M; Edge AS
    J Biol Chem; 2016 Sep; 291(40):21096-21109. PubMed ID: 27542412
    [TBL] [Abstract][Full Text] [Related]  

  • 16. HYPK coordinates degradation of polyneddylated proteins by autophagy.
    Ghosh DK; Ranjan A
    Autophagy; 2022 Aug; 18(8):1763-1784. PubMed ID: 34836490
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Multiple E3 ligases act as antiviral factors against SARS-CoV-2 via inducing the ubiquitination and degradation of ORF9b.
    Yu M; Li J; Gao W; Li Z; Zhang W
    J Virol; 2024 Jun; 98(6):e0162423. PubMed ID: 38709105
    [TBL] [Abstract][Full Text] [Related]  

  • 18. NEDD4L downregulates autophagy and cell growth by modulating ULK1 and a glutamine transporter.
    Lee DE; Yoo JE; Kim J; Kim S; Kim S; Lee H; Cheong H
    Cell Death Dis; 2020 Jan; 11(1):38. PubMed ID: 31959741
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Cul3-KLHL20 Ubiquitin Ligase Governs the Turnover of ULK1 and VPS34 Complexes to Control Autophagy Termination.
    Liu CC; Lin YC; Chen YH; Chen CM; Pang LY; Chen HA; Wu PR; Lin MY; Jiang ST; Tsai TF; Chen RH
    Mol Cell; 2016 Jan; 61(1):84-97. PubMed ID: 26687681
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The giant E3 ligase HUWE1 is linked to tumorigenesis, spermatogenesis, intellectual disability, and inflammatory diseases.
    Qi L; Xu X; Qi X
    Front Cell Infect Microbiol; 2022; 12():905906. PubMed ID: 35937685
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.