These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

207 related articles for article (PubMed ID: 34503187)

  • 1. Targeting Amino Acid Metabolic Reprogramming via L-Type Amino Acid Transporter 1 (LAT1) for Endocrine-Resistant Breast Cancer.
    Shindo H; Harada-Shoji N; Ebata A; Sato M; Soga T; Miyashita M; Tada H; Kawai M; Kosaka S; Onuki K; Usami S; Furumoto S; Hayashi S; Abe T; Suzuki T; Ishida T; Sasano H
    Cancers (Basel); 2021 Aug; 13(17):. PubMed ID: 34503187
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Targeting L-type amino acid transporter 1 in innate and adaptive T cells efficiently controls skin inflammation.
    Cibrian D; Castillo-González R; Fernández-Gallego N; de la Fuente H; Jorge I; Saiz ML; Punzón C; Ramírez-Huesca M; Vicente-Manzanares M; Fresno M; Daudén E; Fraga-Fernandez J; Vazquez J; Aragonés J; Sánchez-Madrid F
    J Allergy Clin Immunol; 2020 Jan; 145(1):199-214.e11. PubMed ID: 31605740
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Targeting amino acid transport in metastatic castration-resistant prostate cancer: effects on cell cycle, cell growth, and tumor development.
    Wang Q; Tiffen J; Bailey CG; Lehman ML; Ritchie W; Fazli L; Metierre C; Feng YJ; Li E; Gleave M; Buchanan G; Nelson CC; Rasko JE; Holst J
    J Natl Cancer Inst; 2013 Oct; 105(19):1463-73. PubMed ID: 24052624
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The LAT1 inhibitor JPH203 suppresses the growth of castration-resistant prostate cancer through a CD24-mediated mechanism.
    Saito S; Ando K; Sakamoto S; Xu M; Yamada Y; Rii J; Kanaoka S; Wei J; Zhao X; Pae S; Kanesaka M; Goto Y; Sazuka T; Imamura Y; Reien Y; Hamaguchi-Suzuki N; Saito S; Hirayama Y; Hashimoto H; Kanai Y; Ichikawa T; Anzai N
    Cancer Sci; 2024 Jul; 115(7):2461-2472. PubMed ID: 38655663
    [TBL] [Abstract][Full Text] [Related]  

  • 5. EGF-activated PI3K/Akt signalling coordinates leucine uptake by regulating LAT3 expression in prostate cancer.
    Zhang BK; Moran AM; Bailey CG; Rasko JEJ; Holst J; Wang Q
    Cell Commun Signal; 2019 Jul; 17(1):83. PubMed ID: 31345230
    [TBL] [Abstract][Full Text] [Related]  

  • 6. L-type amino acid transporter 1, LAT1, in growth hormone-producing pituitary tumor cells.
    Satou M; Wang J; Nakano-Tateno T; Teramachi M; Suzuki T; Hayashi K; Lamothe S; Hao Y; Kurata H; Sugimoto H; Chik C; Tateno T
    Mol Cell Endocrinol; 2020 Sep; 515():110868. PubMed ID: 32579901
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Phosphoproteomics revealed cellular signals immediately responding to disruption of cancer amino acid homeostasis induced by inhibition of L-type amino acid transporter 1.
    Okanishi H; Ohgaki R; Xu M; Endou H; Kanai Y
    Cancer Metab; 2022 Nov; 10(1):18. PubMed ID: 36357940
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Selective Inhibition of L-type Amino Acid Transporter 1 Suppresses Cell Proliferation in Ovarian Clear Cell Carcinoma.
    Sekine M; Koh I; Nakamoto K; Nosaka S; Tomono K; Sugimoto J; Kudo Y
    Anticancer Res; 2023 Jun; 43(6):2509-2517. PubMed ID: 37247931
    [TBL] [Abstract][Full Text] [Related]  

  • 9. LAT1 inhibitor JPH203 sensitizes cancer cells to radiation by enhancing radiation-induced cellular senescence.
    Bo T; Kobayashi S; Inanami O; Fujii J; Nakajima O; Ito T; Yasui H
    Transl Oncol; 2021 Nov; 14(11):101212. PubMed ID: 34461558
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Amino acid transporter LAT1 (SLC7A5) as a molecular target for cancer diagnosis and therapeutics.
    Kanai Y
    Pharmacol Ther; 2022 Feb; 230():107964. PubMed ID: 34390745
    [TBL] [Abstract][Full Text] [Related]  

  • 11. L-type amino acid transport and cancer: targeting the mTORC1 pathway to inhibit neoplasia.
    Wang Q; Holst J
    Am J Cancer Res; 2015; 5(4):1281-94. PubMed ID: 26101697
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Prostate Cancer Cells in Different Androgen Receptor Status Employ Different Leucine Transporters.
    Otsuki H; Kimura T; Yamaga T; Kosaka T; Suehiro JI; Sakurai H
    Prostate; 2017 Feb; 77(2):222-233. PubMed ID: 27696482
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Structure-activity relations of leucine derivatives reveal critical moieties for cellular uptake and activation of mTORC1-mediated signaling.
    Nagamori S; Wiriyasermkul P; Okuda S; Kojima N; Hari Y; Kiyonaka S; Mori Y; Tominaga H; Ohgaki R; Kanai Y
    Amino Acids; 2016 Apr; 48(4):1045-1058. PubMed ID: 26724922
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Expression of L-type amino acid transporter 1 as a molecular target for prognostic and therapeutic indicators in bladder carcinoma.
    Maimaiti M; Sakamoto S; Yamada Y; Sugiura M; Rii J; Takeuchi N; Imamura Y; Furihata T; Ando K; Higuchi K; Xu M; Sazuka T; Nakamura K; Kaneda A; Kanai Y; Kyprianou N; Ikehara Y; Anzai N; Ichikawa T
    Sci Rep; 2020 Jan; 10(1):1292. PubMed ID: 31992742
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The Adipose Tissue-Derived Secretome (ADS) in Obesity Uniquely Induces L-Type Amino Acid Transporter 1 (LAT1) and mTOR Signaling in Estrogen-Receptor-Positive Breast Cancer Cells.
    Thompson C; Rahman MM; Singh S; Arthur S; Sierra-Bakhshi C; Russell R; Denning K; Sundaram U; Salisbury T
    Int J Mol Sci; 2021 Jun; 22(13):. PubMed ID: 34201429
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Targeted Suppression and Knockout of ASCT2 or LAT1 in Epithelial and Mesenchymal Human Liver Cancer Cells Fail to Inhibit Growth.
    Bothwell PJ; Kron CD; Wittke EF; Czerniak BN; Bode BP
    Int J Mol Sci; 2018 Jul; 19(7):. PubMed ID: 30029480
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Genetic Disruption of the Multifunctional CD98/LAT1 Complex Demonstrates the Key Role of Essential Amino Acid Transport in the Control of mTORC1 and Tumor Growth.
    Cormerais Y; Giuliano S; LeFloch R; Front B; Durivault J; Tambutté E; Massard PA; de la Ballina LR; Endou H; Wempe MF; Palacin M; Parks SK; Pouyssegur J
    Cancer Res; 2016 Aug; 76(15):4481-92. PubMed ID: 27302165
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The Harmonious Interplay of Amino Acid and Monocarboxylate Transporters Induces the Robustness of Cancer Cells.
    Yoshida GJ
    Metabolites; 2021 Jan; 11(1):. PubMed ID: 33401672
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The glutamine transporter ASCT2 (SLC1A5) promotes tumor growth independently of the amino acid transporter LAT1 (SLC7A5).
    Cormerais Y; Massard PA; Vucetic M; Giuliano S; Tambutté E; Durivault J; Vial V; Endou H; Wempe MF; Parks SK; Pouyssegur J
    J Biol Chem; 2018 Feb; 293(8):2877-2887. PubMed ID: 29326164
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Small molecule inhibitors provide insights into the relevance of LAT1 and LAT2 in materno-foetal amino acid transport.
    Zaugg J; Huang X; Ziegler F; Rubin M; Graff J; Müller J; Moser-Hässig R; Powell T; Gertsch J; Altmann KH; Albrecht C
    J Cell Mol Med; 2020 Nov; 24(21):12681-12693. PubMed ID: 33001560
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.