BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

198 related articles for article (PubMed ID: 34508006)

  • 1. Regulation of P2X1 receptors by modulators of the cAMP effectors PKA and EPAC.
    Fong Z; Griffin CS; Large RJ; Hollywood MA; Thornbury KD; Sergeant GP
    Proc Natl Acad Sci U S A; 2021 Sep; 118(37):. PubMed ID: 34508006
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Lipid raft association and cholesterol sensitivity of P2X1-4 receptors for ATP: chimeras and point mutants identify intracellular amino-terminal residues involved in lipid regulation of P2X1 receptors.
    Allsopp RC; Lalo U; Evans RJ
    J Biol Chem; 2010 Oct; 285(43):32770-32777. PubMed ID: 20699225
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The intracellular amino terminus plays a dominant role in desensitization of ATP-gated P2X receptor ion channels.
    Allsopp RC; Evans RJ
    J Biol Chem; 2011 Dec; 286(52):44691-701. PubMed ID: 22027824
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Functional modulation of P2X2 receptors by cyclic AMP-dependent protein kinase.
    Chow YW; Wang HL
    J Neurochem; 1998 Jun; 70(6):2606-12. PubMed ID: 9603227
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Comparative analysis of P2X1, P2X2, P2X3, and P2X4 receptor subunits in rat nodose ganglion neurons.
    Wang L; Feng D; Yan H; Wang Z; Pei L
    PLoS One; 2014; 9(5):e96699. PubMed ID: 24798490
    [TBL] [Abstract][Full Text] [Related]  

  • 6. P2X receptor chimeras highlight roles of the amino terminus to partial agonist efficacy, the carboxyl terminus to recovery from desensitization, and independent regulation of channel transitions.
    Allsopp RC; Farmer LK; Fryatt AG; Evans RJ
    J Biol Chem; 2013 Jul; 288(29):21412-21421. PubMed ID: 23740251
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Molecular basis of selective antagonism of the P2X1 receptor for ATP by NF449 and suramin: contribution of basic amino acids in the cysteine-rich loop.
    El-Ajouz S; Ray D; Allsopp RC; Evans RJ
    Br J Pharmacol; 2012 Jan; 165(2):390-400. PubMed ID: 21671897
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Differential Pharmacophore Definition of the cAMP Binding Sites of Neuritogenic cAMP Sensor-Rapgef2, Protein Kinase A, and Exchange Protein Activated by cAMP in Neuroendocrine Cells Using an Adenine-Based Scaffold.
    Emery AC; Alvarez RA; Eiden MV; Xu W; Siméon FG; Eiden LE
    ACS Chem Neurosci; 2017 Jul; 8(7):1500-1509. PubMed ID: 28290664
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The cAMP effectors Epac and protein kinase a (PKA) are involved in the hepatic cystogenesis of an animal model of autosomal recessive polycystic kidney disease (ARPKD).
    Banales JM; Masyuk TV; Gradilone SA; Masyuk AI; Medina JF; LaRusso NF
    Hepatology; 2009 Jan; 49(1):160-74. PubMed ID: 19065671
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The cAMP effectors PKA and Epac activate endothelial NO synthase through PI3K/Akt pathway in human endothelial cells.
    García-Morales V; Luaces-Regueira M; Campos-Toimil M
    Biochem Pharmacol; 2017 Dec; 145():94-101. PubMed ID: 28912066
    [TBL] [Abstract][Full Text] [Related]  

  • 11. P2X1 and P2X2 receptors in the central nervous system as possible drug targets.
    Hausmann R; Schmalzing G
    CNS Neurol Disord Drug Targets; 2012 Sep; 11(6):675-86. PubMed ID: 22963438
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cyclic AMP induces integrin-mediated cell adhesion through Epac and Rap1 upon stimulation of the beta 2-adrenergic receptor.
    Rangarajan S; Enserink JM; Kuiperij HB; de Rooij J; Price LS; Schwede F; Bos JL
    J Cell Biol; 2003 Feb; 160(4):487-93. PubMed ID: 12578910
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Cyclic adenosine 3'-5'-monophosphate (cAMP) exerts proliferative and anti-proliferative effects in pituitary cells of different types by activating both cAMP-dependent protein kinase A (PKA) and exchange proteins directly activated by cAMP (Epac).
    Vitali E; Peverelli E; Giardino E; Locatelli M; Lasio GB; Beck-Peccoz P; Spada A; Lania AG; Mantovani G
    Mol Cell Endocrinol; 2014 Mar; 383(1-2):193-202. PubMed ID: 24373949
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Heat shock protein 90 inhibitors reduce trafficking of ATP-gated P2X1 receptors and human platelet responsiveness.
    Lalo U; Jones S; Roberts JA; Mahaut-Smith MP; Evans RJ
    J Biol Chem; 2012 Sep; 287(39):32747-54. PubMed ID: 22851178
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Off-target effect of the Epac agonist 8-pCPT-2'-O-Me-cAMP on P2Y12 receptors in blood platelets.
    Herfindal L; Nygaard G; Kopperud R; Krakstad C; Døskeland SO; Selheim F
    Biochem Biophys Res Commun; 2013 Aug; 437(4):603-8. PubMed ID: 23850619
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Cyclic adenosine 5'-monophosphate-stimulated neurotensin secretion is mediated through Rap1 downstream of both Epac and protein kinase A signaling pathways.
    Li J; O'Connor KL; Cheng X; Mei FC; Uchida T; Townsend CM; Evers BM
    Mol Endocrinol; 2007 Jan; 21(1):159-71. PubMed ID: 17068197
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Adenosine Receptor Signaling Targets Both PKA and Epac Pathways to Polarize Dendritic Cells to a Suppressive Phenotype.
    Kayhan M; Koyas A; Akdemir I; Savas AC; Cekic C
    J Immunol; 2019 Dec; 203(12):3247-3255. PubMed ID: 31722989
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Differential signaling of cyclic AMP: opposing effects of exchange protein directly activated by cyclic AMP and cAMP-dependent protein kinase on protein kinase B activation.
    Mei FC; Qiao J; Tsygankova OM; Meinkoth JL; Quilliam LA; Cheng X
    J Biol Chem; 2002 Mar; 277(13):11497-504. PubMed ID: 11801596
    [TBL] [Abstract][Full Text] [Related]  

  • 19. cAMP/PKA antagonizes thrombin-induced inactivation of endothelial myosin light chain phosphatase: role of CPI-17.
    Aslam M; Härtel FV; Arshad M; Gündüz D; Abdallah Y; Sauer H; Piper HM; Noll T
    Cardiovasc Res; 2010 Jul; 87(2):375-84. PubMed ID: 20202976
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Cyclic AMP-dependent protein kinase A and EPAC mediate VIP and secretin stimulation of PAK4 and activation of Na
    Ramos-Alvarez I; Lee L; Jensen RT
    Am J Physiol Gastrointest Liver Physiol; 2019 Feb; 316(2):G263-G277. PubMed ID: 30520694
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.