127 related articles for article (PubMed ID: 34508844)
1. Synthesis of the analogs of plocabulin and their preliminary structure-activity relationship study.
Wang L; Li X; Cui H; Lei X; Liu H; Wang Q; Li Y
Bioorg Med Chem Lett; 2021 Nov; 51():128355. PubMed ID: 34508844
[TBL] [Abstract][Full Text] [Related]
2. Effect of the Marine Polyketide Plocabulin on Tumor Progression.
Turrini E; Maffei F; Fimognari C
Mar Drugs; 2022 Dec; 21(1):. PubMed ID: 36662211
[TBL] [Abstract][Full Text] [Related]
3. Isolation and first total synthesis of PM050489 and PM060184, two new marine anticancer compounds.
Martín MJ; Coello L; Fernández R; Reyes F; Rodríguez A; Murcia C; Garranzo M; Mateo C; Sánchez-Sancho F; Bueno S; de Eguilior C; Francesch A; Munt S; Cuevas C
J Am Chem Soc; 2013 Jul; 135(27):10164-71. PubMed ID: 23750450
[TBL] [Abstract][Full Text] [Related]
4. PM060184, a new tubulin binding agent with potent antitumor activity including P-glycoprotein over-expressing tumors.
Martínez-Díez M; Guillén-Navarro MJ; Pera B; Bouchet BP; Martínez-Leal JF; Barasoain I; Cuevas C; Andreu JM; García-Fernández LF; Díaz JF; Avilés P; Galmarini CM
Biochem Pharmacol; 2014 Apr; 88(3):291-302. PubMed ID: 24486569
[TBL] [Abstract][Full Text] [Related]
5. New interfacial microtubule inhibitors of marine origin, PM050489/PM060184, with potent antitumor activity and a distinct mechanism.
Pera B; Barasoain I; Pantazopoulou A; Canales A; Matesanz R; Rodriguez-Salarichs J; García-Fernandez LF; Moneo V; Jiménez-Barbero J; Galmarini CM; Cuevas C; Peñalva MA; Díaz JF; Andreu JM
ACS Chem Biol; 2013 Sep; 8(9):2084-94. PubMed ID: 23859655
[TBL] [Abstract][Full Text] [Related]
6. Plocabulin, a novel tubulin-binding agent, inhibits angiogenesis by modulation of microtubule dynamics in endothelial cells.
Galmarini CM; Martin M; Bouchet BP; Guillen-Navarro MJ; Martínez-Diez M; Martinez-Leal JF; Akhmanova A; Aviles P
BMC Cancer; 2018 Feb; 18(1):164. PubMed ID: 29415678
[TBL] [Abstract][Full Text] [Related]
7. Molecular basis of resistance to the microtubule-depolymerizing antitumor compound plocabulin.
Pantazopoulou A; Galmarini CM; Peñalva MA
Sci Rep; 2018 Jun; 8(1):8616. PubMed ID: 29872155
[TBL] [Abstract][Full Text] [Related]
8. Design, synthesis and biological evaluation of novel pyrazoline-containing derivatives as potential tubulin assembling inhibitors.
Qin YJ; Li YJ; Jiang AQ; Yang MR; Zhu QZ; Dong H; Zhu HL
Eur J Med Chem; 2015 Apr; 94():447-57. PubMed ID: 25828827
[TBL] [Abstract][Full Text] [Related]
9. Plocabulin Displays Strong Cytotoxic Activity in a Personalized Colon Cancer Patient-Derived 3D Organoid Assay.
Costales-Carrera A; Fernández-Barral A; Bustamante-Madrid P; Guerra L; Cantero R; Barbáchano A; Muñoz A
Mar Drugs; 2019 Nov; 17(11):. PubMed ID: 31752287
[TBL] [Abstract][Full Text] [Related]
10. Synthesis and evaluation of new 2-chloro-4-aminopyrimidine and 2,6-dimethyl-4-aminopyrimidine derivatives as tubulin polymerization inhibitors.
Xu S; An B; Li Y; Luo X; Li X; Jia X
Bioorg Med Chem Lett; 2018 Jun; 28(10):1769-1775. PubMed ID: 29673981
[TBL] [Abstract][Full Text] [Related]
11. First-in-human phase I study of the microtubule inhibitor plocabulin in patients with advanced solid tumors.
Elez E; Gomez-Roca C; Soto Matos-Pita A; Argiles G; Valentin T; Coronado C; Iglesias J; Macarulla T; Betrian S; Fudio S; Zaragoza K; Tabernero J; Delord JP
Invest New Drugs; 2019 Aug; 37(4):674-683. PubMed ID: 30411218
[TBL] [Abstract][Full Text] [Related]
12. Synthesis, anticancer activity and molecular docking studies on a series of heterocyclic trans-cyanocombretastatin analogues as antitubulin agents.
Penthala NR; Zong H; Ketkar A; Madadi NR; Janganati V; Eoff RL; Guzman ML; Crooks PA
Eur J Med Chem; 2015 Mar; 92():212-20. PubMed ID: 25557492
[TBL] [Abstract][Full Text] [Related]
13. Discovery of an indole-substituted furanone with tubulin polymerization inhibition activity.
Mowery P; Filkorn MM; Hurysz B; Kwansare DO; Lafferty MM; McFadden MA; Neerukonda ND; Patel RR; Pierce K; Sockett KA; Truax NJ; Webster NR; Pelkey ET
Bioorg Med Chem Lett; 2021 Jun; 41():127991. PubMed ID: 33775833
[TBL] [Abstract][Full Text] [Related]
14. Synthesis, anti-cancer evaluation of benzenesulfonamide derivatives as potent tubulin-targeting agents.
Yang J; Yang S; Zhou S; Lu D; Ji L; Li Z; Yu S; Meng X
Eur J Med Chem; 2016 Oct; 122():488-496. PubMed ID: 27423028
[TBL] [Abstract][Full Text] [Related]
15. Synthesis and biological evaluation of truncated α-tubulin-binding pironetin analogues lacking alkyl pendants in the side chain or the dihydropyrone ring.
Paños J; Díaz-Oltra S; Sánchez-Peris M; García-Pla J; Murga J; Falomir E; Carda M; Redondo-Horcajo M; Díaz JF; Barasoain I; Marco JA
Org Biomol Chem; 2013 Sep; 11(35):5809-26. PubMed ID: 23892508
[TBL] [Abstract][Full Text] [Related]
16. Design, synthesis, and biological evaluation of combretabenzodiazepines: a novel class of anti-tubulin agents.
Galli U; Travelli C; Aprile S; Arrigoni E; Torretta S; Grosa G; Massarotti A; Sorba G; Canonico PL; Genazzani AA; Tron GC
J Med Chem; 2015 Feb; 58(3):1345-57. PubMed ID: 25584687
[TBL] [Abstract][Full Text] [Related]
17. A 2-step synthesis of Combretastatin A-4 and derivatives as potent tubulin assembly inhibitors.
Barnes NG; Parker AW; Ahmed Mal Ullah AA; Ragazzon PA; Hadfield JA
Bioorg Med Chem; 2020 Oct; 28(19):115684. PubMed ID: 32912434
[TBL] [Abstract][Full Text] [Related]
18. Synthesis and biological evaluation of podophyllotoxin congeners as tubulin polymerization inhibitors.
Kamal A; Srinivasa Reddy T; Polepalli S; Shalini N; Reddy VG; Subba Rao AV; Jain N; Shankaraiah N
Bioorg Med Chem; 2014 Oct; 22(19):5466-75. PubMed ID: 25131956
[TBL] [Abstract][Full Text] [Related]
19. Design, Synthesis, and in vitro Evaluation of Tubulin-Targeting Dibenzothiazines with Antiproliferative Activity as a Novel Heterocycle Building Block.
Guerra WD; Lucena-Agell D; Hortigüela R; Rossi RA; Fernando Díaz J; Padrón JM; Barolo SM
ChemMedChem; 2021 Oct; 16(19):3003-3016. PubMed ID: 34231318
[TBL] [Abstract][Full Text] [Related]
20. Discovery of highly potent tubulin polymerization inhibitors: Design, synthesis, and structure-activity relationships of novel 2,7-diaryl-[1,2,4]triazolo[1,5-a]pyrimidines.
Huo XS; Jian XE; Ou-Yang J; Chen L; Yang F; Lv DX; You WW; Rao JJ; Zhao PL
Eur J Med Chem; 2021 Aug; 220():113449. PubMed ID: 33895499
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
