BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

191 related articles for article (PubMed ID: 34513672)

  • 1. Valproic Acid Regulates HR and Cell Cycle Through MUS81-pRPA2 Pathway in Response to Hydroxyurea.
    Su B; Lim D; Tian Z; Liu G; Ding C; Cai Z; Chen C; Zhang F; Feng Z
    Front Oncol; 2021; 11():681278. PubMed ID: 34513672
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Valproic acid sensitizes breast cancer cells to hydroxyurea through inhibiting RPA2 hyperphosphorylation-mediated DNA repair pathway.
    Tian Y; Liu G; Wang H; Tian Z; Cai Z; Zhang F; Luo Y; Wang S; Guo G; Wang X; Powell S; Feng Z
    DNA Repair (Amst); 2017 Oct; 58():1-12. PubMed ID: 28837865
    [TBL] [Abstract][Full Text] [Related]  

  • 3. VPA mediates bidirectional regulation of cell cycle progression through the PPP2R2A-Chk1 signaling axis in response to HU.
    Su B; Lim D; Qi C; Zhang Z; Wang J; Zhang F; Dong C; Feng Z
    Cell Death Dis; 2023 Feb; 14(2):114. PubMed ID: 36781846
    [TBL] [Abstract][Full Text] [Related]  

  • 4. 2-hexyl-4-pentynoic acid, a potential therapeutic for breast carcinoma by influencing RPA2 hyperphosphorylation-mediated DNA repair.
    Ding W; Lim D; Wang Z; Cai Z; Liu G; Zhang F; Feng Z
    DNA Repair (Amst); 2020 Nov; 95():102940. PubMed ID: 32795962
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Human Mus81 and FANCB independently contribute to repair of DNA damage during replication.
    Nomura Y; Adachi N; Koyama H
    Genes Cells; 2007 Oct; 12(10):1111-22. PubMed ID: 17903171
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Replication checkpoint kinase Cds1 regulates Mus81 to preserve genome integrity during replication stress.
    Kai M; Boddy MN; Russell P; Wang TS
    Genes Dev; 2005 Apr; 19(8):919-32. PubMed ID: 15805465
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Hydroxyurea synergizes with valproic acid in wild-type p53 acute myeloid leukaemia.
    Leitch C; Osdal T; Andresen V; Molland M; Kristiansen S; Nguyen XN; Bruserud Ø; Gjertsen BT; McCormack E
    Oncotarget; 2016 Feb; 7(7):8105-18. PubMed ID: 26812881
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Valproic acid causes radiosensitivity of breast cancer cells
    Luo Y; Wang H; Zhao X; Dong C; Zhang F; Guo G; Guo G; Wang X; Powell SN; Feng Z
    Toxicol Res (Camb); 2016 May; 5(3):859-870. PubMed ID: 30090395
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Induction of apoptosis and modulation of homologous recombination DNA repair pathway in prostate cancer cells by the combination of AZD2461 and valproic acid.
    Sargazi S; Saravani R; Zavar Reza J; Jaliani HZ; Mirinejad S; Rezaei Z; Zarei S
    EXCLI J; 2019; 18():485-498. PubMed ID: 31423128
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mus81 knockdown improves chemosensitivity of hepatocellular carcinoma cells by inducing S-phase arrest and promoting apoptosis through CHK1 pathway.
    Wu F; Chen WJ; Yan L; Tan GQ; Li WT; Zhu XJ; Ge XC; Liu JW; Wang BL
    Cancer Med; 2016 Feb; 5(2):370-85. PubMed ID: 26714930
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Distinct roles of BRCA2 in replication fork protection in response to hydroxyurea and DNA interstrand cross-links.
    Rickman KA; Noonan RJ; Lach FP; Sridhar S; Wang AT; Abhyankar A; Huang A; Kelly M; Auerbach AD; Smogorzewska A
    Genes Dev; 2020 Jun; 34(11-12):832-846. PubMed ID: 32354836
    [TBL] [Abstract][Full Text] [Related]  

  • 12. MUS81 Inhibition Increases the Sensitivity to Therapy Effect in Epithelial Ovarian Cancer via Regulating CyclinB Pathway.
    Zhong A; Zheng H; Zhang H; Sun J; Shen J; Deng M; Chen M; Lu R; Guo L
    J Cancer; 2019; 10(10):2276-2287. PubMed ID: 31258731
    [TBL] [Abstract][Full Text] [Related]  

  • 13. ERK1 and ERK2 kinases activate hydroxyurea-induced S-phase checkpoint in MCF7 cells by mediating ATR activation.
    Wei F; Xie Y; He L; Tao L; Tang D
    Cell Signal; 2011 Jan; 23(1):259-68. PubMed ID: 20840867
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Effects of hydroxyurea and aphidicolin on phosphorylation of ataxia telangiectasia mutated on Ser 1981 and histone H2AX on Ser 139 in relation to cell cycle phase and induction of apoptosis.
    Kurose A; Tanaka T; Huang X; Traganos F; Dai W; Darzynkiewicz Z
    Cytometry A; 2006 Apr; 69(4):212-21. PubMed ID: 16528719
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Characterization of valproic acid-initiated homologous recombination.
    Sha K; Winn LM
    Birth Defects Res B Dev Reprod Toxicol; 2010 Apr; 89(2):124-32. PubMed ID: 20437471
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Histone deacetylase inhibitors and hydroxyurea modulate the cell cycle and cooperatively induce apoptosis.
    Krämer OH; Knauer SK; Zimmermann D; Stauber RH; Heinzel T
    Oncogene; 2008 Jan; 27(6):732-40. PubMed ID: 17653085
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Replication checkpoint enforced by kinases Cds1 and Chk1.
    Boddy MN; Furnari B; Mondesert O; Russell P
    Science; 1998 May; 280(5365):909-12. PubMed ID: 9572736
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Inhibition of MUS81 improves the chemical sensitivity of olaparib by regulating MCM2 in epithelial ovarian cancer.
    Zhong A; Zhang H; Xie S; Deng M; Zheng H; Wang Y; Chen M; Lu R; Guo L
    Oncol Rep; 2018 Apr; 39(4):1747-1756. PubMed ID: 29393493
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Basis for the checkpoint signal specificity that regulates Chk1 and Cds1 protein kinases.
    Brondello JM; Boddy MN; Furnari B; Russell P
    Mol Cell Biol; 1999 Jun; 19(6):4262-9. PubMed ID: 10330167
    [TBL] [Abstract][Full Text] [Related]  

  • 20. RECQ5 Helicase Cooperates with MUS81 Endonuclease in Processing Stalled Replication Forks at Common Fragile Sites during Mitosis.
    Di Marco S; Hasanova Z; Kanagaraj R; Chappidi N; Altmannova V; Menon S; Sedlackova H; Langhoff J; Surendranath K; Hühn D; Bhowmick R; Marini V; Ferrari S; Hickson ID; Krejci L; Janscak P
    Mol Cell; 2017 Jun; 66(5):658-671.e8. PubMed ID: 28575661
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.