These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

174 related articles for article (PubMed ID: 34515168)

  • 1. Role of Endothelial Prolyl-4-Hydroxylase Domain Protein/Hypoxia-Inducible Factor Axis in Acute Kidney Injury.
    Tiwari R; Kapitsinou PP
    Nephron; 2022; 146(3):243-248. PubMed ID: 34515168
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Inhibition of Endothelial PHD2 Suppresses Post-Ischemic Kidney Inflammation through Hypoxia-Inducible Factor-1.
    Rajendran G; Schonfeld MP; Tiwari R; Huang S; Torosyan R; Fields T; Park J; Susztak K; Kapitsinou PP
    J Am Soc Nephrol; 2020 Mar; 31(3):501-516. PubMed ID: 31996410
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Inhibition of hypoxia-inducible factor-prolyl hydroxylation protects from cyclophosphamide-induced bladder injury and urinary dysfunction.
    Clayton DB; Tong CMC; Li B; Taylor AS; De S; Mason MD; Dudley AG; Davidoff O; Kobayashi H; Haase VH
    Am J Physiol Renal Physiol; 2022 Jul; 323(1):F81-F91. PubMed ID: 35499237
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Hypoxia-inducible factor-1 (HIF-1) promotes its degradation by induction of HIF-alpha-prolyl-4-hydroxylases.
    Marxsen JH; Stengel P; Doege K; Heikkinen P; Jokilehto T; Wagner T; Jelkmann W; Jaakkola P; Metzen E
    Biochem J; 2004 Aug; 381(Pt 3):761-7. PubMed ID: 15104534
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Hypoxia-inducible factor prolyl-4-hydroxylation in FOXD1 lineage cells is essential for normal kidney development.
    Kobayashi H; Liu J; Urrutia AA; Burmakin M; Ishii K; Rajan M; Davidoff O; Saifudeen Z; Haase VH
    Kidney Int; 2017 Dec; 92(6):1370-1383. PubMed ID: 28847650
    [TBL] [Abstract][Full Text] [Related]  

  • 6. HIF-prolyl hydroxylases in the rat kidney: physiologic expression patterns and regulation in acute kidney injury.
    Schödel J; Klanke B; Weidemann A; Buchholz B; Bernhardt W; Bertog M; Amann K; Korbmacher C; Wiesener M; Warnecke C; Kurtz A; Eckardt KU; Willam C
    Am J Pathol; 2009 May; 174(5):1663-74. PubMed ID: 19349364
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Depletion of PHD3 protects heart from ischemia/reperfusion injury by inhibiting cardiomyocyte apoptosis.
    Xie L; Pi X; Wang Z; He J; Willis MS; Patterson C
    J Mol Cell Cardiol; 2015 Mar; 80():156-65. PubMed ID: 25633836
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Changes in Hypoxia-Inducible Factor-1 (HIF-1) and Regulatory Prolyl Hydroxylase (PHD) Enzymes Following Hypoxic-Ischemic Injury in the Neonatal Rat.
    Chu HX; Jones NM
    Neurochem Res; 2016 Mar; 41(3):515-22. PubMed ID: 26108712
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Preischemic targeting of HIF prolyl hydroxylation inhibits fibrosis associated with acute kidney injury.
    Kapitsinou PP; Jaffe J; Michael M; Swan CE; Duffy KJ; Erickson-Miller CL; Haase VH
    Am J Physiol Renal Physiol; 2012 May; 302(9):F1172-9. PubMed ID: 22262480
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Preclinical Characterization of Vadadustat (AKB-6548), an Oral Small Molecule Hypoxia-Inducible Factor Prolyl-4-Hydroxylase Inhibitor, for the Potential Treatment of Renal Anemia.
    Zuk A; Si Z; Loi S; Bommegowda S; Hoivik D; Danthi S; Molnar G; Csizmadia V; Rabinowitz M
    J Pharmacol Exp Ther; 2022 Oct; 383(1):11-24. PubMed ID: 35926869
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Prolyl hydroxylase 3 (PHD3) is essential for hypoxic regulation of neutrophilic inflammation in humans and mice.
    Walmsley SR; Chilvers ER; Thompson AA; Vaughan K; Marriott HM; Parker LC; Shaw G; Parmar S; Schneider M; Sabroe I; Dockrell DH; Milo M; Taylor CT; Johnson RS; Pugh CW; Ratcliffe PJ; Maxwell PH; Carmeliet P; Whyte MK
    J Clin Invest; 2011 Mar; 121(3):1053-63. PubMed ID: 21317538
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Prolyl Hydroxylase Inhibition Mitigates Allograft Injury During Liver Transplantation.
    Harnoss JM; Cai J; Hinterkopf S; Radhakrishnan P; Schmitt A; Dupovac M; Nees LK; Strowitzki MJ; Taylor CT; Schneider M
    Transplantation; 2022 Oct; 106(10):e430-e440. PubMed ID: 35849574
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The regulation, localization, and functions of oxygen-sensing prolyl hydroxylase PHD3.
    Jaakkola PM; Rantanen K
    Biol Chem; 2013 Apr; 394(4):449-57. PubMed ID: 23380539
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Complement C1q is hydroxylated by collagen prolyl 4 hydroxylase and is sensitive to off-target inhibition by prolyl hydroxylase domain inhibitors that stabilize hypoxia-inducible factor.
    Kiriakidis S; Hoer SS; Burrows N; Biddlecome G; Khan MN; Thinnes CC; Schofield CJ; Rogers N; Botto M; Paleolog E; Maxwell PH
    Kidney Int; 2017 Oct; 92(4):900-908. PubMed ID: 28506759
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Preconditioned suppression of prolyl-hydroxylases attenuates renal injury but increases mortality in septic murine models.
    Schindler K; Bondeva T; Schindler C; Claus RA; Franke S; Wolf G
    Nephrol Dial Transplant; 2016 Jul; 31(7):1100-13. PubMed ID: 26908768
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Differential function of the prolyl hydroxylases PHD1, PHD2, and PHD3 in the regulation of hypoxia-inducible factor.
    Appelhoff RJ; Tian YM; Raval RR; Turley H; Harris AL; Pugh CW; Ratcliffe PJ; Gleadle JM
    J Biol Chem; 2004 Sep; 279(37):38458-65. PubMed ID: 15247232
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Disruption of hypoxia-inducible transcription factor-prolyl hydroxylase domain-1 (PHD-1-/-) attenuates ex vivo myocardial ischemia/reperfusion injury through hypoxia-inducible factor-1α transcription factor and its target genes in mice.
    Adluri RS; Thirunavukkarasu M; Dunna NR; Zhan L; Oriowo B; Takeda K; Sanchez JA; Otani H; Maulik G; Fong GH; Maulik N
    Antioxid Redox Signal; 2011 Oct; 15(7):1789-97. PubMed ID: 21083501
    [TBL] [Abstract][Full Text] [Related]  

  • 18. miR-21 contributes to renal protection by targeting prolyl hydroxylase domain protein 2 in delayed ischaemic preconditioning.
    Jiao X; Xu X; Fang Y; Zhang H; Liang M; Teng J; Ding X
    Nephrology (Carlton); 2017 May; 22(5):366-373. PubMed ID: 27030384
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Deletion of prolyl hydroxylase domain proteins (PHD1, PHD3) stabilizes hypoxia inducible factor-1 alpha, promotes neovascularization, and improves perfusion in a murine model of hind-limb ischemia.
    Rishi MT; Selvaraju V; Thirunavukkarasu M; Shaikh IA; Takeda K; Fong GH; Palesty JA; Sanchez JA; Maulik N
    Microvasc Res; 2015 Jan; 97():181-8. PubMed ID: 25446011
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Hypoxia-inducible factor prolyl hydroxylase inhibitor roxadustat (FG-4592) protects against cisplatin-induced acute kidney injury.
    Yang Y; Yu X; Zhang Y; Ding G; Zhu C; Huang S; Jia Z; Zhang A
    Clin Sci (Lond); 2018 Apr; 132(7):825-838. PubMed ID: 29581249
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.