BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

197 related articles for article (PubMed ID: 34516556)

  • 1. Cancer-associated IDH mutations induce Glut1 expression and glucose metabolic disorders through a PI3K/Akt/mTORC1-Hif1α axis.
    Liu X; Yamaguchi K; Takane K; Zhu C; Hirata M; Hikiba Y; Maeda S; Furukawa Y; Ikenoue T
    PLoS One; 2021; 16(9):e0257090. PubMed ID: 34516556
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Signaling through the Phosphatidylinositol 3-Kinase (PI3K)/Mammalian Target of Rapamycin (mTOR) Axis Is Responsible for Aerobic Glycolysis mediated by Glucose Transporter in Epidermal Growth Factor Receptor (EGFR)-mutated Lung Adenocarcinoma.
    Makinoshima H; Takita M; Saruwatari K; Umemura S; Obata Y; Ishii G; Matsumoto S; Sugiyama E; Ochiai A; Abe R; Goto K; Esumi H; Tsuchihara K
    J Biol Chem; 2015 Jul; 290(28):17495-504. PubMed ID: 26023239
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Rapamycin (mTORC1 inhibitor) reduces the production of lactate and 2-hydroxyglutarate oncometabolites in IDH1 mutant fibrosarcoma cells.
    Hujber Z; Petővári G; Szoboszlai N; Dankó T; Nagy N; Kriston C; Krencz I; Paku S; Ozohanics O; Drahos L; Jeney A; Sebestyén A
    J Exp Clin Cancer Res; 2017 Jun; 36(1):74. PubMed ID: 28578659
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Orexin A affects HepG2 human hepatocellular carcinoma cells glucose metabolism via HIF-1α-dependent and -independent mechanism.
    Wan X; Liu Y; Zhao Y; Sun X; Fan D; Guo L
    PLoS One; 2017; 12(9):e0184213. PubMed ID: 28886081
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Arginine ADP-ribosyltransferase 1 Regulates Glycolysis in Colorectal Cancer via the PI3K/AKT/HIF1α Pathway.
    Long WB; Pu X; Tang Y; Li M; Liu Y; She Q; Wang YL; Guo QX
    Curr Med Sci; 2022 Aug; 42(4):733-741. PubMed ID: 35798928
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Halofuginone inhibits colorectal cancer growth through suppression of Akt/mTORC1 signaling and glucose metabolism.
    Chen GQ; Tang CF; Shi XK; Lin CY; Fatima S; Pan XH; Yang DJ; Zhang G; Lu AP; Lin SH; Bian ZX
    Oncotarget; 2015 Sep; 6(27):24148-62. PubMed ID: 26160839
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Regulators of Glucose Metabolism in CD4
    Palmer CS; Hussain T; Duette G; Weller TJ; Ostrowski M; Sada-Ovalle I; Crowe SM
    Int Rev Immunol; 2016 Nov; 35(6):477-488. PubMed ID: 26606199
    [TBL] [Abstract][Full Text] [Related]  

  • 8. S100A2 promotes glycolysis and proliferation via GLUT1 regulation in colorectal cancer.
    Li C; Chen Q; Zhou Y; Niu Y; Wang X; Li X; Zheng H; Wei T; Zhao L; Gao H
    FASEB J; 2020 Oct; 34(10):13333-13344. PubMed ID: 32816365
    [TBL] [Abstract][Full Text] [Related]  

  • 9. miRNA-451 inhibits glioma cell proliferation and invasion by downregulating glucose transporter 1.
    Guo H; Nan Y; Zhen Y; Zhang Y; Guo L; Yu K; Huang Q; Zhong Y
    Tumour Biol; 2016 Oct; 37(10):13751-13761. PubMed ID: 27476171
    [TBL] [Abstract][Full Text] [Related]  

  • 10. MDM2 regulates hypoxic hypoxia-inducible factor 1α stability in an E3 ligase, proteasome, and PTEN-phosphatidylinositol 3-kinase-AKT-dependent manner.
    Joshi S; Singh AR; Durden DL
    J Biol Chem; 2014 Aug; 289(33):22785-22797. PubMed ID: 24982421
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Effects of orexin A on glucose metabolism in human hepatocellular carcinoma in vitro via PI3K/Akt/mTOR-dependent and -independent mechanism.
    Liu Y; Zhao Y; Guo L
    Mol Cell Endocrinol; 2016 Jan; 420():208-16. PubMed ID: 26549689
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Effects of Glut1 gene silencing on proliferation, differentiation, and apoptosis of colorectal cancer cells by targeting the TGF-β/PI3K-AKT-mTOR signaling pathway.
    Wu XL; Wang LK; Yang DD; Qu M; Yang YJ; Guo F; Han L; Xue J
    J Cell Biochem; 2018 Feb; 119(2):2356-2367. PubMed ID: 28884839
    [TBL] [Abstract][Full Text] [Related]  

  • 13. PDK1 regulation of mTOR and hypoxia-inducible factor 1 integrate metabolism and migration of CD8+ T cells.
    Finlay DK; Rosenzweig E; Sinclair LV; Feijoo-Carnero C; Hukelmann JL; Rolf J; Panteleyev AA; Okkenhaug K; Cantrell DA
    J Exp Med; 2012 Dec; 209(13):2441-53. PubMed ID: 23183047
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Roles of glucose transporter-1 and the phosphatidylinositol 3‑kinase/protein kinase B pathway in cancer radioresistance (review).
    Fang J; Zhou SH; Fan J; Yan SX
    Mol Med Rep; 2015 Mar; 11(3):1573-81. PubMed ID: 25376370
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Isocitrate dehydrogenase (IDH) mutations promote a reversible ZEB1/microRNA (miR)-200-dependent epithelial-mesenchymal transition (EMT).
    Grassian AR; Lin F; Barrett R; Liu Y; Jiang W; Korpal M; Astley H; Gitterman D; Henley T; Howes R; Levell J; Korn JM; Pagliarini R
    J Biol Chem; 2012 Dec; 287(50):42180-94. PubMed ID: 23038259
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Oncogenic activation of the PI3K/Akt pathway promotes cellular glucose uptake by downregulating the expression of thioredoxin-interacting protein.
    Hong SY; Yu FX; Luo Y; Hagen T
    Cell Signal; 2016 May; 28(5):377-383. PubMed ID: 26826652
    [TBL] [Abstract][Full Text] [Related]  

  • 17. TNFα and IL-17 cooperatively stimulate glucose metabolism and growth factor production in human colorectal cancer cells.
    Straus DS
    Mol Cancer; 2013 Jul; 12():78. PubMed ID: 23866118
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Cancer-associated isocitrate dehydrogenase 1 (IDH1) R132H mutation and d-2-hydroxyglutarate stimulate glutamine metabolism under hypoxia.
    Reitman ZJ; Duncan CG; Poteet E; Winters A; Yan LJ; Gooden DM; Spasojevic I; Boros LG; Yang SH; Yan H
    J Biol Chem; 2014 Aug; 289(34):23318-28. PubMed ID: 24986863
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Enhanced expression of glucose transporter-1 in vascular smooth muscle cells via the Akt/tuberous sclerosis complex subunit 2 (TSC2)/mammalian target of rapamycin (mTOR)/ribosomal S6 protein kinase (S6K) pathway in experimental renal failure.
    Lin CY; Hsu SC; Lee HS; Lin SH; Tsai CS; Huang SM; Shih CC; Hsu YJ
    J Vasc Surg; 2013 Feb; 57(2):475-85. PubMed ID: 23265586
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Wild‑type IDH1 affects cell migration by modulating the PI3K/AKT/mTOR pathway in primary glioblastoma cells.
    Shen X; Wu S; Zhang J; Li M; Xu F; Wang A; Lei Y; Zhu G
    Mol Med Rep; 2020 Sep; 22(3):1949-1957. PubMed ID: 32705169
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.