BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

138 related articles for article (PubMed ID: 34520118)

  • 1. Identification of a small molecule splicing inhibitor targeting UHM domains.
    Kobayashi A; Clément MJ; Craveur P; El Hage K; Salone JM; Bollot G; Pastré D; Maucuer A
    FEBS J; 2022 Feb; 289(3):682-698. PubMed ID: 34520118
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The pre-mRNA splicing and transcription factor Tat-SF1 is a functional partner of the spliceosome SF3b1 subunit via a U2AF homology motif interface.
    Loerch S; Leach JR; Horner SW; Maji D; Jenkins JL; Pulvino MJ; Kielkopf CL
    J Biol Chem; 2019 Feb; 294(8):2892-2902. PubMed ID: 30567737
    [TBL] [Abstract][Full Text] [Related]  

  • 3. U2AF
    Tari M; Manceau V; de Matha Salone J; Kobayashi A; Pastré D; Maucuer A
    EMBO Rep; 2019 Aug; 20(8):e47604. PubMed ID: 31271494
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Cancer-relevant splicing factor CAPERα engages the essential splicing factor SF3b155 in a specific ternary complex.
    Loerch S; Maucuer A; Manceau V; Green MR; Kielkopf CL
    J Biol Chem; 2014 Jun; 289(25):17325-37. PubMed ID: 24795046
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Identification of phenothiazine derivatives as UHM-binding inhibitors of early spliceosome assembly.
    Jagtap PKA; Kubelka T; Soni K; Will CL; Garg D; Sippel C; Kapp TG; Potukuchi HK; Schorpp K; Hadian K; Kessler H; Lührmann R; Hausch F; Bach T; Sattler M
    Nat Commun; 2020 Nov; 11(1):5621. PubMed ID: 33159082
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A UHM-ULM interface with unusual structural features contributes to U2AF2 and SF3B1 association for pre-mRNA splicing.
    Galardi JW; Bela VN; Jeffery N; He X; Glasser E; Loerch S; Jenkins JL; Pulvino MJ; Boutz PL; Kielkopf CL
    J Biol Chem; 2022 Aug; 298(8):102224. PubMed ID: 35780835
    [TBL] [Abstract][Full Text] [Related]  

  • 7. SPF45/RBM17-dependent, but not U2AF-dependent, splicing in a distinct subset of human short introns.
    Fukumura K; Yoshimoto R; Sperotto L; Kang HS; Hirose T; Inoue K; Sattler M; Mayeda A
    Nat Commun; 2021 Aug; 12(1):4910. PubMed ID: 34389706
    [TBL] [Abstract][Full Text] [Related]  

  • 8. SAP30BP interacts with RBM17/SPF45 to promote splicing in a subset of human short introns.
    Fukumura K; Sperotto L; Seuß S; Kang HS; Yoshimoto R; Sattler M; Mayeda A
    Cell Rep; 2023 Dec; 42(12):113534. PubMed ID: 38065098
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Multiple U2AF65 binding sites within SF3b155: thermodynamic and spectroscopic characterization of protein-protein interactions among pre-mRNA splicing factors.
    Thickman KR; Swenson MC; Kabogo JM; Gryczynski Z; Kielkopf CL
    J Mol Biol; 2006 Feb; 356(3):664-83. PubMed ID: 16376933
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Different requirements of the kinase and UHM domains of KIS for its nuclear localization and binding to splicing factors.
    Manceau V; Kielkopf CL; Sobel A; Maucuer A
    J Mol Biol; 2008 Sep; 381(3):748-62. PubMed ID: 18588901
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Dimerization and protein binding specificity of the U2AF homology motif of the splicing factor Puf60.
    Corsini L; Hothorn M; Stier G; Rybin V; Scheffzek K; Gibson TJ; Sattler M
    J Biol Chem; 2009 Jan; 284(1):630-639. PubMed ID: 18974054
    [TBL] [Abstract][Full Text] [Related]  

  • 12. U2AF-homology motif interactions are required for alternative splicing regulation by SPF45.
    Corsini L; Bonnal S; Basquin J; Hothorn M; Scheffzek K; Valcárcel J; Sattler M
    Nat Struct Mol Biol; 2007 Jul; 14(7):620-9. PubMed ID: 17589525
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Modulation of HIV-1 gene expression by binding of a ULM motif in the Rev protein to UHM-containing splicing factors.
    Pabis M; Corsini L; Vincendeau M; Tripsianes K; Gibson TJ; Brack-Werner R; Sattler M
    Nucleic Acids Res; 2019 May; 47(9):4859-4871. PubMed ID: 30892606
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Rational Design of Cyclic Peptide Inhibitors of U2AF Homology Motif (UHM) Domains To Modulate Pre-mRNA Splicing.
    Jagtap PK; Garg D; Kapp TG; Will CL; Demmer O; Lührmann R; Kessler H; Sattler M
    J Med Chem; 2016 Nov; 59(22):10190-10197. PubMed ID: 27753493
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A synthetic small molecule stalls pre-mRNA splicing by promoting an early-stage U2AF2-RNA complex.
    Chatrikhi R; Feeney CF; Pulvino MJ; Alachouzos G; MacRae AJ; Falls Z; Rai S; Brennessel WW; Jenkins JL; Walter MJ; Graubert TA; Samudrala R; Jurica MS; Frontier AJ; Kielkopf CL
    Cell Chem Biol; 2021 Aug; 28(8):1145-1157.e6. PubMed ID: 33689684
    [TBL] [Abstract][Full Text] [Related]  

  • 16. UHM-ULM interactions in the RBM39-U2AF65 splicing-factor complex.
    Stepanyuk GA; Serrano P; Peralta E; Farr CL; Axelrod HL; Geralt M; Das D; Chiu HJ; Jaroszewski L; Deacon AM; Lesley SA; Elsliger MA; Godzik A; Wilson IA; Wüthrich K; Salomon DR; Williamson JR
    Acta Crystallogr D Struct Biol; 2016 Apr; 72(Pt 4):497-511. PubMed ID: 27050129
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Molecular Architecture of SF3b and Structural Consequences of Its Cancer-Related Mutations.
    Cretu C; Schmitzová J; Ponce-Salvatierra A; Dybkov O; De Laurentiis EI; Sharma K; Will CL; Urlaub H; Lührmann R; Pena V
    Mol Cell; 2016 Oct; 64(2):307-319. PubMed ID: 27720643
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Nonsense-Mediated RNA Decay Is a Unique Vulnerability of Cancer Cells Harboring
    Cheruiyot A; Li S; Nonavinkere Srivatsan S; Ahmed T; Chen Y; Lemacon DS; Li Y; Yang Z; Wadugu BA; Warner WA; Pruett-Miller SM; Obeng EA; Link DC; He D; Xiao F; Wang X; Bailis JM; Walter MJ; You Z
    Cancer Res; 2021 Sep; 81(17):4499-4513. PubMed ID: 34215620
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Aberrant splicing and defective mRNA production induced by somatic spliceosome mutations in myelodysplasia.
    Shiozawa Y; Malcovati L; Gallì A; Sato-Otsubo A; Kataoka K; Sato Y; Watatani Y; Suzuki H; Yoshizato T; Yoshida K; Sanada M; Makishima H; Shiraishi Y; Chiba K; Hellström-Lindberg E; Miyano S; Ogawa S; Cazzola M
    Nat Commun; 2018 Sep; 9(1):3649. PubMed ID: 30194306
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A novel protein-protein interaction in the RES (REtention and Splicing) complex.
    Tripsianes K; Friberg A; Barrandon C; Brooks M; van Tilbeurgh H; Seraphin B; Sattler M
    J Biol Chem; 2014 Oct; 289(41):28640-50. PubMed ID: 25160624
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.