BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

337 related articles for article (PubMed ID: 34520398)

  • 1. Breast cancer-derived GM-CSF regulates arginase 1 in myeloid cells to promote an immunosuppressive microenvironment.
    Su X; Xu Y; Fox GC; Xiang J; Kwakwa KA; Davis JL; Belle JI; Lee WC; Wong WH; Fontana F; Hernandez-Aya LF; Kobayashi T; Tomasson HM; Su J; Bakewell SJ; Stewart SA; Egbulefu C; Karmakar P; Meyer MA; Veis DJ; DeNardo DG; Lanza GM; Achilefu S; Weilbaecher KN
    J Clin Invest; 2021 Oct; 131(20):. PubMed ID: 34520398
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Inhibition of arginase by CB-1158 blocks myeloid cell-mediated immune suppression in the tumor microenvironment.
    Steggerda SM; Bennett MK; Chen J; Emberley E; Huang T; Janes JR; Li W; MacKinnon AL; Makkouk A; Marguier G; Murray PJ; Neou S; Pan A; Parlati F; Rodriguez MLM; Van de Velde LA; Wang T; Works M; Zhang J; Zhang W; Gross MI
    J Immunother Cancer; 2017 Dec; 5(1):101. PubMed ID: 29254508
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Deficiency of Kruppel-like factor KLF4 in mammary tumor cells inhibits tumor growth and pulmonary metastasis and is accompanied by compromised recruitment of myeloid-derived suppressor cells.
    Yu F; Shi Y; Wang J; Li J; Fan D; Ai W
    Int J Cancer; 2013 Dec; 133(12):2872-83. PubMed ID: 23737434
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Arginase 1-Based Immune Modulatory Vaccines Induce Anticancer Immunity and Synergize with Anti-PD-1 Checkpoint Blockade.
    Aaboe Jørgensen M; Ugel S; Linder Hübbe M; Carretta M; Perez-Penco M; Weis-Banke SE; Martinenaite E; Kopp K; Chapellier M; Adamo A; De Sanctis F; Frusteri C; Iezzi M; Zocca MB; Hargbøll Madsen D; Wakatsuki Pedersen A; Bronte V; Andersen MH
    Cancer Immunol Res; 2021 Nov; 9(11):1316-1326. PubMed ID: 34518197
    [TBL] [Abstract][Full Text] [Related]  

  • 5. GM-CSF promotes the immunosuppressive activity of glioma-infiltrating myeloid cells through interleukin-4 receptor-α.
    Kohanbash G; McKaveney K; Sakaki M; Ueda R; Mintz AH; Amankulor N; Fujita M; Ohlfest JR; Okada H
    Cancer Res; 2013 Nov; 73(21):6413-23. PubMed ID: 24030977
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Activation of GM-CSF and TLR2 signaling synergistically enhances antigen-specific antitumor immunity and modulates the tumor microenvironment.
    Yan WL; Wu CC; Shen KY; Liu SJ
    J Immunother Cancer; 2021 Oct; 9(10):. PubMed ID: 34599024
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Chimeric antigen receptor T cells shape myeloid cell function within the tumor microenvironment through IFN-γ and GM-CSF.
    Spear P; Barber A; Rynda-Apple A; Sentman CL
    J Immunol; 2012 Jun; 188(12):6389-98. PubMed ID: 22586039
    [TBL] [Abstract][Full Text] [Related]  

  • 8. STAT5 is activated in macrophages by breast cancer cell-derived factors and regulates macrophage function in the tumor microenvironment.
    Jesser EA; Brady NJ; Huggins DN; Witschen PM; O'Connor CH; Schwertfeger KL
    Breast Cancer Res; 2021 Nov; 23(1):104. PubMed ID: 34743736
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Tumor-Derived GM-CSF Promotes Granulocyte Immunosuppression in Mesothelioma Patients.
    Khanna S; Graef S; Mussai F; Thomas A; Wali N; Yenidunya BG; Yuan C; Morrow B; Zhang J; Korangy F; Greten TF; Steinberg SM; Stetler-Stevenson M; Middleton G; De Santo C; Hassan R
    Clin Cancer Res; 2018 Jun; 24(12):2859-2872. PubMed ID: 29602801
    [No Abstract]   [Full Text] [Related]  

  • 10. Adipose Progenitor Cell Secretion of GM-CSF and MMP9 Promotes a Stromal and Immunological Microenvironment That Supports Breast Cancer Progression.
    Reggiani F; Labanca V; Mancuso P; Rabascio C; Talarico G; Orecchioni S; Manconi A; Bertolini F
    Cancer Res; 2017 Sep; 77(18):5169-5182. PubMed ID: 28754674
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Tumor-associated GM-CSF overexpression induces immunoinhibitory molecules via STAT3 in myeloid-suppressor cells infiltrating liver metastases.
    Thorn M; Guha P; Cunetta M; Espat NJ; Miller G; Junghans RP; Katz SC
    Cancer Gene Ther; 2016 Jun; 23(6):188-98. PubMed ID: 27199222
    [TBL] [Abstract][Full Text] [Related]  

  • 12. GM-CSF is one of the main breast tumor-derived soluble factors involved in the differentiation of CD11b-Gr1- bone marrow progenitor cells into myeloid-derived suppressor cells.
    Morales JK; Kmieciak M; Knutson KL; Bear HD; Manjili MH
    Breast Cancer Res Treat; 2010 Aug; 123(1):39-49. PubMed ID: 19898981
    [TBL] [Abstract][Full Text] [Related]  

  • 13. PPARγ Contributes to Immunity Induced by Cancer Cell Vaccines That Secrete GM-CSF.
    Goyal G; Wong K; Nirschl CJ; Souders N; Neuberg D; Anandasabapathy N; Dranoff G
    Cancer Immunol Res; 2018 Jun; 6(6):723-732. PubMed ID: 29669721
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Suppression of Myeloid Cell Arginase Activity leads to Therapeutic Response in a NSCLC Mouse Model by Activating Anti-Tumor Immunity.
    Miret JJ; Kirschmeier P; Koyama S; Zhu M; Li YY; Naito Y; Wu M; Malladi VS; Huang W; Walker W; Palakurthi S; Dranoff G; Hammerman PS; Pecot CV; Wong KK; Akbay EA
    J Immunother Cancer; 2019 Feb; 7(1):32. PubMed ID: 30728077
    [TBL] [Abstract][Full Text] [Related]  

  • 15. M-MDSC
    Aintablian A; Strozniak S; Heuer M; Lutz MB
    Front Immunol; 2023; 14():1130600. PubMed ID: 37275910
    [TBL] [Abstract][Full Text] [Related]  

  • 16. TGF-β Enhances Immunosuppression of Myeloid-Derived Suppressor Cells to Induce Transplant Immune Tolerance Through Affecting Arg-1 Expression.
    Cao P; Sun Z; Zhang F; Zhang J; Zheng X; Yu B; Zhao Y; Wang W; Wang W
    Front Immunol; 2022; 13():919674. PubMed ID: 35874674
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Myeloid cells in circulation and tumor microenvironment of breast cancer patients.
    Toor SM; Syed Khaja AS; El Salhat H; Faour I; Kanbar J; Quadri AA; Albashir M; Elkord E
    Cancer Immunol Immunother; 2017 Jun; 66(6):753-764. PubMed ID: 28283696
    [TBL] [Abstract][Full Text] [Related]  

  • 18. GM-CSF drives myelopoiesis, recruitment and polarisation of tumour-associated macrophages in cholangiocarcinoma and systemic blockade facilitates antitumour immunity.
    Ruffolo LI; Jackson KM; Kuhlers PC; Dale BS; Figueroa Guilliani NM; Ullman NA; Burchard PR; Qin SS; Juviler PG; Keilson JM; Morrison AB; Georger M; Jewell R; Calvi LM; Nywening TM; O'Dell MR; Hezel AF; De Las Casas L; Lesinski GB; Yeh JJ; Hernandez-Alejandro R; Belt BA; Linehan DC
    Gut; 2022 Jul; 71(7):1386-1398. PubMed ID: 34413131
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Hierarchy of immunosuppressive strength among myeloid-derived suppressor cell subsets is determined by GM-CSF.
    Dolcetti L; Peranzoni E; Ugel S; Marigo I; Fernandez Gomez A; Mesa C; Geilich M; Winkels G; Traggiai E; Casati A; Grassi F; Bronte V
    Eur J Immunol; 2010 Jan; 40(1):22-35. PubMed ID: 19941314
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Aerobic Glycolysis Controls Myeloid-Derived Suppressor Cells and Tumor Immunity via a Specific CEBPB Isoform in Triple-Negative Breast Cancer.
    Li W; Tanikawa T; Kryczek I; Xia H; Li G; Wu K; Wei S; Zhao L; Vatan L; Wen B; Shu P; Sun D; Kleer C; Wicha M; Sabel M; Tao K; Wang G; Zou W
    Cell Metab; 2018 Jul; 28(1):87-103.e6. PubMed ID: 29805099
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.