387 related articles for article (PubMed ID: 34522215)
1. Alzheimer's disease-causing presenilin-1 mutations have deleterious effects on mitochondrial function.
Han J; Park H; Maharana C; Gwon AR; Park J; Baek SH; Bae HG; Cho Y; Kim HK; Sul JH; Lee J; Kim E; Kim J; Cho Y; Park S; Palomera LF; Arumugam TV; Mattson MP; Jo DG
Theranostics; 2021; 11(18):8855-8873. PubMed ID: 34522215
[TBL] [Abstract][Full Text] [Related]
2. Familial Alzheimer's disease-associated presenilin-1 alters cerebellar activity and calcium homeostasis.
Sepulveda-Falla D; Barrera-Ocampo A; Hagel C; Korwitz A; Vinueza-Veloz MF; Zhou K; Schonewille M; Zhou H; Velazquez-Perez L; Rodriguez-Labrada R; Villegas A; Ferrer I; Lopera F; Langer T; De Zeeuw CI; Glatzel M
J Clin Invest; 2014 Apr; 124(4):1552-67. PubMed ID: 24569455
[TBL] [Abstract][Full Text] [Related]
3. Endogenous expression of FAD-linked PS1 impairs proliferation, neuronal differentiation and survival of adult hippocampal progenitors.
Veeraraghavalu K; Choi SH; Zhang X; Sisodia SS
Mol Neurodegener; 2013 Oct; 8():41. PubMed ID: 24138759
[TBL] [Abstract][Full Text] [Related]
4. Susceptibility to cellular stress in PS1 mutant N2a cells is associated with mitochondrial defects and altered calcium homeostasis.
Rojas-Charry L; Calero-Martinez S; Morganti C; Morciano G; Park K; Hagel C; Marciniak SJ; Glatzel M; Pinton P; Sepulveda-Falla D
Sci Rep; 2020 Apr; 10(1):6455. PubMed ID: 32296078
[TBL] [Abstract][Full Text] [Related]
5. Calcium Signaling and Mitochondrial Function in Presenilin 2 Knock-Out Mice: Looking for Any Loss-of-Function Phenotype Related to Alzheimer's Disease.
Rossi A; Galla L; Gomiero C; Zentilin L; Giacca M; Giorgio V; Calì T; Pozzan T; Greotti E; Pizzo P
Cells; 2021 Jan; 10(2):. PubMed ID: 33494218
[TBL] [Abstract][Full Text] [Related]
6. Deficits in Enrichment-Dependent Neurogenesis and Enhanced Anxiety Behaviors Mediated by Expression of Alzheimer's Disease-Linked Ps1 Variants Are Rescued by Microglial Depletion.
Ortega-Martinez S; Palla N; Zhang X; Lipman E; Sisodia SS
J Neurosci; 2019 Aug; 39(34):6766-6780. PubMed ID: 31217332
[TBL] [Abstract][Full Text] [Related]
7. Enhanced accumulation of phosphorylated alpha-synuclein and elevated beta-amyloid 42/40 ratio caused by expression of the presenilin-1 deltaT440 mutant associated with familial Lewy body disease and variant Alzheimer's disease.
Kaneko H; Kakita A; Kasuga K; Nozaki H; Ishikawa A; Miyashita A; Kuwano R; Ito G; Iwatsubo T; Takahashi H; Nishizawa M; Onodera O; Sisodia SS; Ikeuchi T
J Neurosci; 2007 Nov; 27(48):13092-7. PubMed ID: 18045903
[TBL] [Abstract][Full Text] [Related]
8. G206D Mutation of Presenilin-1 Reduces Pen2 Interaction, Increases Aβ42/Aβ40 Ratio and Elevates ER Ca(2+) Accumulation.
Chen WT; Hsieh YF; Huang YJ; Lin CC; Lin YT; Liu YC; Lien CC; Cheng IH
Mol Neurobiol; 2015 Dec; 52(3):1835-1849. PubMed ID: 25394380
[TBL] [Abstract][Full Text] [Related]
9. Defects in mitochondrial dynamics and metabolomic signatures of evolving energetic stress in mouse models of familial Alzheimer's disease.
Trushina E; Nemutlu E; Zhang S; Christensen T; Camp J; Mesa J; Siddiqui A; Tamura Y; Sesaki H; Wengenack TM; Dzeja PP; Poduslo JF
PLoS One; 2012; 7(2):e32737. PubMed ID: 22393443
[TBL] [Abstract][Full Text] [Related]
10. Presenilin 1 Regulates Membrane Homeostatic Pathways that are Dysregulated in Alzheimer's Disease.
Deaton CA; Johnson GVW
J Alzheimers Dis; 2020; 77(3):961-977. PubMed ID: 32804090
[TBL] [Abstract][Full Text] [Related]
11. Wild-type presenilin 1 protects against Alzheimer disease mutation-induced amyloid pathology.
Wang R; Wang B; He W; Zheng H
J Biol Chem; 2006 Jun; 281(22):15330-6. PubMed ID: 16574645
[TBL] [Abstract][Full Text] [Related]
12. A neuronal model of Alzheimer's disease: an insight into the mechanisms of oxidative stress-mediated mitochondrial injury.
Sompol P; Ittarat W; Tangpong J; Chen Y; Doubinskaia I; Batinic-Haberle I; Abdul HM; Butterfield DA; St Clair DK
Neuroscience; 2008 Apr; 153(1):120-30. PubMed ID: 18353561
[TBL] [Abstract][Full Text] [Related]
13. Repression of transcription of presenilin-1 inhibits γ-secretase independent ER Ca²⁺ leak that is impaired by FAD mutations.
Das HK; Tchedre K; Mueller B
J Neurochem; 2012 Aug; 122(3):487-500. PubMed ID: 22607268
[TBL] [Abstract][Full Text] [Related]
14. Presenilins form ER Ca2+ leak channels, a function disrupted by familial Alzheimer's disease-linked mutations.
Tu H; Nelson O; Bezprozvanny A; Wang Z; Lee SF; Hao YH; Serneels L; De Strooper B; Yu G; Bezprozvanny I
Cell; 2006 Sep; 126(5):981-93. PubMed ID: 16959576
[TBL] [Abstract][Full Text] [Related]
15. Presenilin-1 mutations sensitize neurons to DNA damage-induced death by a mechanism involving perturbed calcium homeostasis and activation of calpains and caspase-12.
Chan SL; Culmsee C; Haughey N; Klapper W; Mattson MP
Neurobiol Dis; 2002 Oct; 11(1):2-19. PubMed ID: 12460542
[TBL] [Abstract][Full Text] [Related]
16. Neurons overexpressing mutant presenilin-1 are more sensitive to apoptosis induced by endoplasmic reticulum-Golgi stress.
Terro F; Czech C; Esclaire F; Elyaman W; Yardin C; Baclet MC; Touchet N; Tremp G; Pradier L; Hugon J
J Neurosci Res; 2002 Aug; 69(4):530-9. PubMed ID: 12210846
[TBL] [Abstract][Full Text] [Related]
17. Early Presymptomatic Changes in the Proteome of Mitochondria-Associated Membrane in the APP/PS1 Mouse Model of Alzheimer's Disease.
Völgyi K; Badics K; Sialana FJ; Gulyássy P; Udvari EB; Kis V; Drahos L; Lubec G; Kékesi KA; Juhász G
Mol Neurobiol; 2018 Oct; 55(10):7839-7857. PubMed ID: 29468564
[TBL] [Abstract][Full Text] [Related]
18. An Alzheimer's disease-relevant presenilin-1 mutation augments amyloid-beta-induced oligodendrocyte dysfunction.
Desai MK; Guercio BJ; Narrow WC; Bowers WJ
Glia; 2011 Apr; 59(4):627-40. PubMed ID: 21294162
[TBL] [Abstract][Full Text] [Related]
19. Familial Alzheimer's disease-linked presenilin-1 mutation M146V affects store-operated calcium entry: does gain look like loss?
Ryazantseva M; Skobeleva K; Kaznacheyeva E
Biochimie; 2013 Jul; 95(7):1506-9. PubMed ID: 23624206
[TBL] [Abstract][Full Text] [Related]
20. Thapsigargin affects presenilin-2 but not presenilin-1 regulation in SK-N-BE cells.
Rivabene R; Visentin S; Piscopo P; De Nuccio C; Crestini A; Svetoni F; Rosa P; Confaloni A
Exp Biol Med (Maywood); 2014 Feb; 239(2):213-24. PubMed ID: 24363250
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
