These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

398 related articles for article (PubMed ID: 34525338)

  • 1. Mutations in the adenosine deaminase ADAR1 that prevent endogenous Z-RNA binding induce Aicardi-Goutières-syndrome-like encephalopathy.
    Nakahama T; Kato Y; Shibuya T; Inoue M; Kim JI; Vongpipatana T; Todo H; Xing Y; Kawahara Y
    Immunity; 2021 Sep; 54(9):1976-1988.e7. PubMed ID: 34525338
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Adenosine-to-inosine editing of endogenous Z-form RNA by the deaminase ADAR1 prevents spontaneous MAVS-dependent type I interferon responses.
    Tang Q; Rigby RE; Young GR; Hvidt AK; Davis T; Tan TK; Bridgeman A; Townsend AR; Kassiotis G; Rehwinkel J
    Immunity; 2021 Sep; 54(9):1961-1975.e5. PubMed ID: 34525337
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The RNA-editing enzyme ADAR1: a regulatory hub that tunes multiple dsRNA-sensing pathways.
    Nakahama T; Kawahara Y
    Int Immunol; 2023 Mar; 35(3):123-133. PubMed ID: 36469491
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Deciphering the Biological Significance of ADAR1-Z-RNA Interactions.
    Nakahama T; Kawahara Y
    Int J Mol Sci; 2021 Oct; 22(21):. PubMed ID: 34768866
    [TBL] [Abstract][Full Text] [Related]  

  • 5. ADAR1 interaction with Z-RNA promotes editing of endogenous double-stranded RNA and prevents MDA5-dependent immune activation.
    de Reuver R; Dierick E; Wiernicki B; Staes K; Seys L; De Meester E; Muyldermans T; Botzki A; Lambrecht BN; Van Nieuwerburgh F; Vandenabeele P; Maelfait J
    Cell Rep; 2021 Aug; 36(6):109500. PubMed ID: 34380029
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Aicardi-Goutières syndrome-associated mutation at ADAR1 gene locus activates innate immune response in mouse brain.
    Guo X; Wiley CA; Steinman RA; Sheng Y; Ji B; Wang J; Zhang L; Wang T; Zenatai M; Billiar TR; Wang Q
    J Neuroinflammation; 2021 Jul; 18(1):169. PubMed ID: 34332594
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Human ADAR1 Prevents Endogenous RNA from Triggering Translational Shutdown.
    Chung H; Calis JJA; Wu X; Sun T; Yu Y; Sarbanes SL; Dao Thi VL; Shilvock AR; Hoffmann HH; Rosenberg BR; Rice CM
    Cell; 2018 Feb; 172(4):811-824.e14. PubMed ID: 29395325
    [TBL] [Abstract][Full Text] [Related]  

  • 8. RNA editing at a limited number of sites is sufficient to prevent MDA5 activation in the mouse brain.
    Kim JI; Nakahama T; Yamasaki R; Costa Cruz PH; Vongpipatana T; Inoue M; Kanou N; Xing Y; Todo H; Shibuya T; Kato Y; Kawahara Y
    PLoS Genet; 2021 May; 17(5):e1009516. PubMed ID: 33983932
    [TBL] [Abstract][Full Text] [Related]  

  • 9. An Aicardi-Goutières Syndrome-Causative Point Mutation in
    Inoue M; Nakahama T; Yamasaki R; Shibuya T; Kim JI; Todo H; Xing Y; Kato Y; Morii E; Kawahara Y
    J Immunol; 2021 Dec; 207(12):3016-3027. PubMed ID: 34772697
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mutations in ADAR1 cause Aicardi-Goutières syndrome associated with a type I interferon signature.
    Rice GI; Kasher PR; Forte GM; Mannion NM; Greenwood SM; Szynkiewicz M; Dickerson JE; Bhaskar SS; Zampini M; Briggs TA; Jenkinson EM; Bacino CA; Battini R; Bertini E; Brogan PA; Brueton LA; Carpanelli M; De Laet C; de Lonlay P; del Toro M; Desguerre I; Fazzi E; Garcia-Cazorla A; Heiberg A; Kawaguchi M; Kumar R; Lin JP; Lourenco CM; Male AM; Marques W; Mignot C; Olivieri I; Orcesi S; Prabhakar P; Rasmussen M; Robinson RA; Rozenberg F; Schmidt JL; Steindl K; Tan TY; van der Merwe WG; Vanderver A; Vassallo G; Wakeling EL; Wassmer E; Whittaker E; Livingston JH; Lebon P; Suzuki T; McLaughlin PJ; Keegan LP; O'Connell MA; Lovell SC; Crow YJ
    Nat Genet; 2012 Nov; 44(11):1243-8. PubMed ID: 23001123
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The RNA-editing enzyme ADAR1 controls innate immune responses to RNA.
    Mannion NM; Greenwood SM; Young R; Cox S; Brindle J; Read D; Nellåker C; Vesely C; Ponting CP; McLaughlin PJ; Jantsch MF; Dorin J; Adams IR; Scadden AD; Ohman M; Keegan LP; O'Connell MA
    Cell Rep; 2014 Nov; 9(4):1482-94. PubMed ID: 25456137
    [TBL] [Abstract][Full Text] [Related]  

  • 12. ADAR1 Zα domain P195A mutation activates the MDA5-dependent RNA-sensing signaling pathway in brain without decreasing overall RNA editing.
    Guo X; Liu S; Sheng Y; Zenati M; Billiar T; Herbert A; Wang Q
    Cell Rep; 2023 Jul; 42(7):112733. PubMed ID: 37421629
    [TBL] [Abstract][Full Text] [Related]  

  • 13. ADAR1 prevents autoinflammation by suppressing spontaneous ZBP1 activation.
    de Reuver R; Verdonck S; Dierick E; Nemegeer J; Hessmann E; Ahmad S; Jans M; Blancke G; Van Nieuwerburgh F; Botzki A; Vereecke L; van Loo G; Declercq W; Hur S; Vandenabeele P; Maelfait J
    Nature; 2022 Jul; 607(7920):784-789. PubMed ID: 35859175
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The role of RNA editing enzyme ADAR1 in human disease.
    Song B; Shiromoto Y; Minakuchi M; Nishikura K
    Wiley Interdiscip Rev RNA; 2022 Jan; 13(1):e1665. PubMed ID: 34105255
    [TBL] [Abstract][Full Text] [Related]  

  • 15. ADAR1 entraps sinister cellular dsRNAs, thresholding antiviral responses.
    Keegan LP; Vukić D; O'Connell MA
    Trends Immunol; 2021 Nov; 42(11):953-955. PubMed ID: 34642093
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Protein kinase R and the integrated stress response drive immunopathology caused by mutations in the RNA deaminase ADAR1.
    Maurano M; Snyder JM; Connelly C; Henao-Mejia J; Sidrauski C; Stetson DB
    Immunity; 2021 Sep; 54(9):1948-1960.e5. PubMed ID: 34343497
    [TBL] [Abstract][Full Text] [Related]  

  • 17. RNA editing by ADAR1 prevents MDA5 sensing of endogenous dsRNA as nonself.
    Liddicoat BJ; Piskol R; Chalk AM; Ramaswami G; Higuchi M; Hartner JC; Li JB; Seeburg PH; Walkley CR
    Science; 2015 Sep; 349(6252):1115-20. PubMed ID: 26275108
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The ADAR1 editome reveals drivers of editing-specificity for ADAR1-isoforms.
    Kleinova R; Rajendra V; Leuchtenberger AF; Lo Giudice C; Vesely C; Kapoor U; Tanzer A; Derdak S; Picardi E; Jantsch MF
    Nucleic Acids Res; 2023 May; 51(9):4191-4207. PubMed ID: 37026479
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Decoupling expression and editing preferences of ADAR1 p150 and p110 isoforms.
    Sun T; Yu Y; Wu X; Acevedo A; Luo JD; Wang J; Schneider WM; Hurwitz B; Rosenberg BR; Chung H; Rice CM
    Proc Natl Acad Sci U S A; 2021 Mar; 118(12):. PubMed ID: 33723056
    [TBL] [Abstract][Full Text] [Related]  

  • 20. ADAR1 averts fatal type I interferon induction by ZBP1.
    Jiao H; Wachsmuth L; Wolf S; Lohmann J; Nagata M; Kaya GG; Oikonomou N; Kondylis V; Rogg M; Diebold M; Tröder SE; Zevnik B; Prinz M; Schell C; Young GR; Kassiotis G; Pasparakis M
    Nature; 2022 Jul; 607(7920):776-783. PubMed ID: 35859176
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 20.