225 related articles for article (PubMed ID: 34526504)
1. USP11 controls R-loops by regulating senataxin proteostasis.
Jurga M; Abugable AA; Goldman ASH; El-Khamisy SF
Nat Commun; 2021 Sep; 12(1):5156. PubMed ID: 34526504
[TBL] [Abstract][Full Text] [Related]
2. Mutation in senataxin alters the mechanism of R-loop resolution in amyotrophic lateral sclerosis 4.
Kannan A; Cuartas J; Gangwani P; Branzei D; Gangwani L
Brain; 2022 Sep; 145(9):3072-3094. PubMed ID: 35045161
[TBL] [Abstract][Full Text] [Related]
3. SETX (senataxin), the helicase mutated in AOA2 and ALS4, functions in autophagy regulation.
Richard P; Feng S; Tsai YL; Li W; Rinchetti P; Muhith U; Irizarry-Cole J; Stolz K; Sanz LA; Hartono S; Hoque M; Tadesse S; Seitz H; Lotti F; Hirano M; Chédin F; Tian B; Manley JL
Autophagy; 2021 Aug; 17(8):1889-1906. PubMed ID: 32686621
[TBL] [Abstract][Full Text] [Related]
4. Human senataxin is a bona fide R-loop resolving enzyme and transcription termination factor.
Hasanova Z; Klapstova V; Porrua O; Stefl R; Sebesta M
Nucleic Acids Res; 2023 Apr; 51(6):2818-2837. PubMed ID: 36864660
[TBL] [Abstract][Full Text] [Related]
5. Senataxin: A key actor in RNA metabolism, genome integrity and neurodegeneration.
Giannini M; Porrua O
Biochimie; 2024 Feb; 217():10-19. PubMed ID: 37558082
[TBL] [Abstract][Full Text] [Related]
6. SUMOylated Senataxin functions in genome stability, RNA degradation, and stress granule disassembly, and is linked with inherited ataxia and motor neuron disease.
Bennett CL; La Spada AR
Mol Genet Genomic Med; 2021 Dec; 9(12):e1745. PubMed ID: 34263556
[TBL] [Abstract][Full Text] [Related]
7. R-loop-derived cytoplasmic RNA-DNA hybrids activate an immune response.
Crossley MP; Song C; Bocek MJ; Choi JH; Kousouros JN; Sathirachinda A; Lin C; Brickner JR; Bai G; Lans H; Vermeulen W; Abu-Remaileh M; Cimprich KA
Nature; 2023 Jan; 613(7942):187-194. PubMed ID: 36544021
[TBL] [Abstract][Full Text] [Related]
8. Hypoxia-induced SETX links replication stress with the unfolded protein response.
Ramachandran S; Ma TS; Griffin J; Ng N; Foskolou IP; Hwang MS; Victori P; Cheng WC; Buffa FM; Leszczynska KB; El-Khamisy SF; Gromak N; Hammond EM
Nat Commun; 2021 Jun; 12(1):3686. PubMed ID: 34140498
[TBL] [Abstract][Full Text] [Related]
9. FANCD2 promotes mitotic rescue from transcription-mediated replication stress in SETX-deficient cancer cells.
Said M; Barra V; Balzano E; Talhaoui I; Pelliccia F; Giunta S; Naim V
Commun Biol; 2022 Dec; 5(1):1395. PubMed ID: 36543851
[TBL] [Abstract][Full Text] [Related]
10. Integrated genome and transcriptome analyses reveal the mechanism of genome instability in ataxia with oculomotor apraxia 2.
Kanagaraj R; Mitter R; Kantidakis T; Edwards MM; Benitez A; Chakravarty P; Fu B; Becherel O; Yang F; Lavin MF; Koren A; Stewart A; West SC
Proc Natl Acad Sci U S A; 2022 Jan; 119(4):. PubMed ID: 35042798
[TBL] [Abstract][Full Text] [Related]
11. Clinical and Molecular Aspects of Senataxin Mutations in Amyotrophic Lateral Sclerosis 4.
Grunseich C; Patankar A; Amaya J; Watts JA; Li D; Ramirez P; Schindler AB; Fischbeck KH; Cheung VG
Ann Neurol; 2020 Apr; 87(4):547-555. PubMed ID: 31957062
[TBL] [Abstract][Full Text] [Related]
12. ΔNp63-Senataxin circuit controls keratinocyte differentiation by promoting the transcriptional termination of epidermal genes.
Gatti V; Fierro C; Compagnone M; La Banca V; Mauriello A; Montanaro M; Scalera S; De Nicola F; Candi E; Ricci F; Fania L; Melino G; Peschiaroli A
Proc Natl Acad Sci U S A; 2022 Mar; 119(10):e2104718119. PubMed ID: 35235452
[TBL] [Abstract][Full Text] [Related]
13. USP11 mediates repair of DNA-protein cross-links by deubiquitinating SPRTN metalloprotease.
Perry M; Biegert M; Kollala SS; Mallard H; Su G; Kodavati M; Kreiling N; Holbrook A; Ghosal G
J Biol Chem; 2021; 296():100396. PubMed ID: 33567341
[TBL] [Abstract][Full Text] [Related]
14. Senataxin deficiency disrupts proteostasis through nucleolar ncRNA-driven protein aggregation.
Wen X; Xu H; Woolley PR; Conway OM; Yao J; Matouschek A; Lambowitz AM; Paull TT
J Cell Biol; 2024 Jul; 223(7):. PubMed ID: 38717338
[TBL] [Abstract][Full Text] [Related]
15. Combined deficiency of Senataxin and DNA-PKcs causes DNA damage accumulation and neurodegeneration in spinal muscular atrophy.
Kannan A; Bhatia K; Branzei D; Gangwani L
Nucleic Acids Res; 2018 Sep; 46(16):8326-8346. PubMed ID: 30010942
[TBL] [Abstract][Full Text] [Related]
16. DDX47 untangles R-loops with only certain other helicases.
Yu Z; Richard S
Trends Cell Biol; 2023 May; 33(5):359-360. PubMed ID: 36914533
[TBL] [Abstract][Full Text] [Related]
17. Mutation of senataxin alters disease-specific transcriptional networks in patients with ataxia with oculomotor apraxia type 2.
Fogel BL; Cho E; Wahnich A; Gao F; Becherel OJ; Wang X; Fike F; Chen L; Criscuolo C; De Michele G; Filla A; Collins A; Hahn AF; Gatti RA; Konopka G; Perlman S; Lavin MF; Geschwind DH; Coppola G
Hum Mol Genet; 2014 Sep; 23(18):4758-69. PubMed ID: 24760770
[TBL] [Abstract][Full Text] [Related]
18. Senataxin: Genome Guardian at the Interface of Transcription and Neurodegeneration.
Groh M; Albulescu LO; Cristini A; Gromak N
J Mol Biol; 2017 Oct; 429(21):3181-3195. PubMed ID: 27771483
[TBL] [Abstract][Full Text] [Related]
19. Senataxin Mutation Reveals How R-Loops Promote Transcription by Blocking DNA Methylation at Gene Promoters.
Grunseich C; Wang IX; Watts JA; Burdick JT; Guber RD; Zhu Z; Bruzel A; Lanman T; Chen K; Schindler AB; Edwards N; Ray-Chaudhury A; Yao J; Lehky T; Piszczek G; Crain B; Fischbeck KH; Cheung VG
Mol Cell; 2018 Feb; 69(3):426-437.e7. PubMed ID: 29395064
[TBL] [Abstract][Full Text] [Related]
20. Premature ovarian ageing following heterozygous loss of Senataxin.
Subramanian GN; Lavin M; Homer HA
Mol Hum Reprod; 2021 Feb; 27(2):. PubMed ID: 33337500
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]