277 related articles for article (PubMed ID: 34529720)
1. Biogenesis of P-TEFb in CD4+ T cells to reverse HIV latency is mediated by protein kinase C (PKC)-independent signaling pathways.
Mbonye U; Leskov K; Shukla M; Valadkhan S; Karn J
PLoS Pathog; 2021 Sep; 17(9):e1009581. PubMed ID: 34529720
[TBL] [Abstract][Full Text] [Related]
2. Phosphorylation of CDK9 at Ser175 enhances HIV transcription and is a marker of activated P-TEFb in CD4(+) T lymphocytes.
Mbonye UR; Gokulrangan G; Datt M; Dobrowolski C; Cooper M; Chance MR; Karn J
PLoS Pathog; 2013; 9(5):e1003338. PubMed ID: 23658523
[TBL] [Abstract][Full Text] [Related]
3. T-cell receptor signaling enhances transcriptional elongation from latent HIV proviruses by activating P-TEFb through an ERK-dependent pathway.
Kim YK; Mbonye U; Hokello J; Karn J
J Mol Biol; 2011 Jul; 410(5):896-916. PubMed ID: 21763495
[TBL] [Abstract][Full Text] [Related]
4. Short Communication: The Broad-Spectrum Histone Deacetylase Inhibitors Vorinostat and Panobinostat Activate Latent HIV in CD4(+) T Cells In Part Through Phosphorylation of the T-Loop of the CDK9 Subunit of P-TEFb.
Jamaluddin MS; Hu PW; Jan Y; Siwak EB; Rice AP
AIDS Res Hum Retroviruses; 2016 Feb; 32(2):169-73. PubMed ID: 26727990
[TBL] [Abstract][Full Text] [Related]
5. Effects of prostratin on Cyclin T1/P-TEFb function and the gene expression profile in primary resting CD4+ T cells.
Sung TL; Rice AP
Retrovirology; 2006 Oct; 3():66. PubMed ID: 17014716
[TBL] [Abstract][Full Text] [Related]
6. Efficient Non-Epigenetic Activation of HIV Latency through the T-Cell Receptor Signalosome.
Hokello J; Sharma AL; Tyagi M
Viruses; 2020 Aug; 12(8):. PubMed ID: 32784426
[TBL] [Abstract][Full Text] [Related]
7. Short communication: SAHA (vorinostat) induces CDK9 Thr-186 (T-loop) phosphorylation in resting CD4+ T cells: implications for reactivation of latent HIV.
Ramakrishnan R; Liu H; Rice AP
AIDS Res Hum Retroviruses; 2015 Jan; 31(1):137-41. PubMed ID: 24528253
[TBL] [Abstract][Full Text] [Related]
8. Cyclin-dependent kinase 7 (CDK7)-mediated phosphorylation of the CDK9 activation loop promotes P-TEFb assembly with Tat and proviral HIV reactivation.
Mbonye U; Wang B; Gokulrangan G; Shi W; Yang S; Karn J
J Biol Chem; 2018 Jun; 293(26):10009-10025. PubMed ID: 29743242
[TBL] [Abstract][Full Text] [Related]
9. An In-Depth Comparison of Latency-Reversing Agent Combinations in Various In Vitro and Ex Vivo HIV-1 Latency Models Identified Bryostatin-1+JQ1 and Ingenol-B+JQ1 to Potently Reactivate Viral Gene Expression.
Darcis G; Kula A; Bouchat S; Fujinaga K; Corazza F; Ait-Ammar A; Delacourt N; Melard A; Kabeya K; Vanhulle C; Van Driessche B; Gatot JS; Cherrier T; Pianowski LF; Gama L; Schwartz C; Vila J; Burny A; Clumeck N; Moutschen M; De Wit S; Peterlin BM; Rouzioux C; Rohr O; Van Lint C
PLoS Pathog; 2015 Jul; 11(7):e1005063. PubMed ID: 26225566
[TBL] [Abstract][Full Text] [Related]
10. Regulation of TAK/P-TEFb in CD4+ T lymphocytes and macrophages.
Rice AP; Herrmann CH
Curr HIV Res; 2003 Oct; 1(4):395-404. PubMed ID: 15049426
[TBL] [Abstract][Full Text] [Related]
11. Heat Shock Protein 90 Facilitates Latent HIV Reactivation through Maintaining the Function of Positive Transcriptional Elongation Factor b (p-TEFb) under Proteasome Inhibition.
Pan XY; Zhao W; Wang CY; Lin J; Zeng XY; Ren RX; Wang K; Xun TR; Shai Y; Liu SW
J Biol Chem; 2016 Dec; 291(50):26177-26187. PubMed ID: 27799305
[TBL] [Abstract][Full Text] [Related]
12. The cell biology of HIV-1 latency and rebound.
Mbonye U; Karn J
Retrovirology; 2024 Apr; 21(1):6. PubMed ID: 38580979
[TBL] [Abstract][Full Text] [Related]
13. Establishment of HIV latency in primary CD4+ cells is due to epigenetic transcriptional silencing and P-TEFb restriction.
Tyagi M; Pearson RJ; Karn J
J Virol; 2010 Jul; 84(13):6425-37. PubMed ID: 20410271
[TBL] [Abstract][Full Text] [Related]
14. Cyclin T1 and CDK9 T-loop phosphorylation are downregulated during establishment of HIV-1 latency in primary resting memory CD4+ T cells.
Budhiraja S; Famiglietti M; Bosque A; Planelles V; Rice AP
J Virol; 2013 Jan; 87(2):1211-20. PubMed ID: 23152527
[TBL] [Abstract][Full Text] [Related]
15. Phosphatase PPM1A negatively regulates P-TEFb function in resting CD4(+) T cells and inhibits HIV-1 gene expression.
Budhiraja S; Ramakrishnan R; Rice AP
Retrovirology; 2012 Jun; 9():52. PubMed ID: 22727189
[TBL] [Abstract][Full Text] [Related]
16. Regulation of cyclin T1 during HIV replication and latency establishment in human memory CD4 T cells.
Couturier J; Orozco AF; Liu H; Budhiraja S; Siwak EB; Nehete PN; Sastry KJ; Rice AP; Lewis DE
Virol J; 2019 Feb; 16(1):22. PubMed ID: 30786885
[TBL] [Abstract][Full Text] [Related]
17. The mTOR Complex Controls HIV Latency.
Besnard E; Hakre S; Kampmann M; Lim HW; Hosmane NN; Martin A; Bassik MC; Verschueren E; Battivelli E; Chan J; Svensson JP; Gramatica A; Conrad RJ; Ott M; Greene WC; Krogan NJ; Siliciano RF; Weissman JS; Verdin E
Cell Host Microbe; 2016 Dec; 20(6):785-797. PubMed ID: 27978436
[TBL] [Abstract][Full Text] [Related]
18. 4-Deoxyphorbol inhibits HIV-1 infection in synergism with antiretroviral drugs and reactivates viral reservoirs through PKC/MEK activation synergizing with vorinostat.
De la Torre-Tarazona HE; Jiménez R; Bueno P; Camarero S; Román L; Fernández-García JL; Beltrán M; Nothias LF; Cachet X; Paolini J; Litaudon M; Alcami J; Bedoya LM
Biochem Pharmacol; 2020 Jul; 177():113937. PubMed ID: 32224142
[TBL] [Abstract][Full Text] [Related]
19. New insights into transcription elongation control of HIV-1 latency and rebound.
Mbonye U; Kizito F; Karn J
Trends Immunol; 2023 Jan; 44(1):60-71. PubMed ID: 36503686
[TBL] [Abstract][Full Text] [Related]
20. A novel bromodomain inhibitor, CPI-203, serves as an HIV-1 latency-reversing agent by activating positive transcription elongation factor b.
Liang T; Zhang X; Lai F; Lin J; Zhou C; Xu X; Tan X; Liu S; Li L
Biochem Pharmacol; 2019 Jun; 164():237-251. PubMed ID: 30991051
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
