These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

216 related articles for article (PubMed ID: 34536927)

  • 1. 4-Flourophenyl-substituted 5H-indeno[1,2-b]pyridinols with enhanced topoisomerase IIα inhibitory activity: Synthesis, biological evaluation, and structure-activity relationships.
    Kunwar S; Hwang SY; Katila P; Seo M; Man Kadayat T; Kwon Y; Lee ES
    Bioorg Chem; 2021 Nov; 116():105349. PubMed ID: 34536927
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Topoisomerase IIα inhibitory and antiproliferative activity of dihydroxylated 2,6-diphenyl-4-fluorophenylpyridines: Design, synthesis, and structure-activity relationships.
    Kunwar S; Hwang SY; Katila P; Man Kadayat T; Jung AR; Kwon Y; Lee ES
    Bioorg Med Chem Lett; 2022 Mar; 60():128606. PubMed ID: 35123005
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis and structure-activity relationships of hydroxylated and halogenated 2,4-diaryl benzofuro[3,2-b]pyridin-7-ols as selective topoisomerase IIα inhibitors.
    Thapa Magar TB; Hee Seo S; Shrestha A; Kim JA; Kunwar S; Bist G; Kwon Y; Lee ES
    Bioorg Chem; 2021 Jun; 111():104884. PubMed ID: 33872925
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Hydroxylated 2,4-diphenyl indenopyridine derivatives as a selective non-intercalative topoisomerase IIα catalytic inhibitor.
    Kadayat TM; Park C; Jun KY; Thapa Magar TB; Bist G; Yoo HY; Kwon Y; Lee ES
    Eur J Med Chem; 2015 Jan; 90():302-14. PubMed ID: 25437617
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Design, synthesis, biological evaluation, structure-activity relationship study, and mode of action of 2-phenol-4,6-dichlorophenyl-pyridines.
    Shrestha A; Park S; Shin S; Man Kadayat T; Bist G; Katila P; Kwon Y; Lee ES
    Bioorg Chem; 2018 Sep; 79():1-18. PubMed ID: 29715635
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Novel 2-aryl-4-(4'-hydroxyphenyl)-5H-indeno[1,2-b]pyridines as potent DNA non-intercalative topoisomerase catalytic inhibitors.
    Park S; Kadayat TM; Jun KY; Thapa Magar TB; Bist G; Shrestha A; Lee ES; Kwon Y
    Eur J Med Chem; 2017 Jan; 125():14-28. PubMed ID: 27643560
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Dihydroxylated 2,6-diphenyl-4-chlorophenylpyridines: Topoisomerase I and IIα dual inhibitors with DNA non-intercalative catalytic activity.
    Bist G; Park S; Song C; Thapa Magar TB; Shrestha A; Kwon Y; Lee ES
    Eur J Med Chem; 2017 Jun; 133():69-84. PubMed ID: 28384547
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Discovery and Biological Evaluations of Halogenated 2,4-Diphenyl Indeno[1,2-
    Kadayat TM; Park S; Shrestha A; Jo H; Hwang SY; Katila P; Shrestha R; Nepal MR; Noh K; Kim SK; Koh WS; Kim KS; Jeon YH; Jeong TC; Kwon Y; Lee ES
    J Med Chem; 2019 Sep; 62(17):8194-8234. PubMed ID: 31398033
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis and SAR study of new hydroxy and chloro-substituted 2,4-diphenyl 5H-chromeno[4,3-b]pyridines as selective topoisomerase IIα-targeting anticancer agents.
    Magar TBT; Seo SH; Kadayat TM; Jo H; Shrestha A; Bist G; Katila P; Kwon Y; Lee ES
    Bioorg Med Chem; 2018 May; 26(8):1909-1919. PubMed ID: 29510948
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis and biological evaluation of 2-phenol-4-chlorophenyl-6-aryl pyridines as topoisomerase II inhibitors and cytotoxic agents.
    Thapa P; Kadayat TM; Park S; Shin S; Thapa Magar TB; Bist G; Shrestha A; Na Y; Kwon Y; Lee ES
    Bioorg Chem; 2016 Jun; 66():145-59. PubMed ID: 27174797
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A new phenolic series of indenopyridinone as topoisomerase inhibitors: Design, synthesis, and structure-activity relationships.
    Shrestha A; Park S; Jang HJ; Katila P; Shrestha R; Kwon Y; Lee ES
    Bioorg Med Chem; 2018 Oct; 26(18):5212-5223. PubMed ID: 30262132
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis and biological activity of 2,4-di-p-phenolyl-6-2-furanyl-pyridine as a potent topoisomerase II poison.
    Karki R; Park C; Jun KY; Kadayat TM; Lee ES; Kwon Y
    Eur J Med Chem; 2015 Jan; 90():360-78. PubMed ID: 25437622
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Discovery of a 2,4-diphenyl-5,6-dihydrobenzo(h)quinolin-8-amine derivative as a novel DNA intercalating topoisomerase IIα poison.
    Kunwar S; Hwang SY; Katila P; Park S; Jeon KH; Kim D; Kadayat TM; Kwon Y; Lee ES
    Eur J Med Chem; 2021 Dec; 226():113860. PubMed ID: 34597897
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis, topoisomerase I and II inhibitory activity, cytotoxicity, and structure-activity relationship study of 2-phenyl- or hydroxylated 2-phenyl-4-aryl-5H-indeno[1,2-b]pyridines.
    Kadayat TM; Song C; Shin S; Magar TB; Bist G; Shrestha A; Thapa P; Na Y; Kwon Y; Lee ES
    Bioorg Med Chem; 2015 Jul; 23(13):3499-512. PubMed ID: 26022080
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A novel indeno[1,2-b]pyridinone derivative, a DNA intercalative human topoisomerase IIα catalytic inhibitor, for caspase 3-independent anticancer activity.
    Jeon KH; Park C; Kadayat TM; Shrestha A; Lee ES; Kwon Y
    Chem Commun (Camb); 2017 Jun; 53(51):6864-6867. PubMed ID: 28604852
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis, computational quantum chemical study, in silico ADMET and molecular docking analysis, in vitro biological evaluation of a novel sulfur heterocyclic thiophene derivative containing 1,2,3-triazole and pyridine moieties as a potential human topoisomerase IIα inhibiting anticancer agent.
    Murugavel S; Ravikumar C; Jaabil G; Alagusundaram P
    Comput Biol Chem; 2019 Apr; 79():73-82. PubMed ID: 30731361
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis, Biological Evaluation and Molecular Docking Study of Cyclic Diarylheptanoids as Potential Anticancer Therapeutics.
    Lu Y; Yin W; Alam MS; Kadi AA; Jahng Y; Kwon Y; Rahman AFMM
    Anticancer Agents Med Chem; 2020; 20(4):464-475. PubMed ID: 31763968
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis, antitumor activity, and structure-activity relationship study of trihydroxylated 2,4,6-triphenyl pyridines as potent and selective topoisomerase II inhibitors.
    Karki R; Park C; Jun KY; Jee JG; Lee JH; Thapa P; Kadayat TM; Kwon Y; Lee ES
    Eur J Med Chem; 2014 Sep; 84():555-65. PubMed ID: 25062006
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A new series of 2-phenol-4-aryl-6-chlorophenyl pyridine derivatives as dual topoisomerase I/II inhibitors: Synthesis, biological evaluation and 3D-QSAR study.
    Karki R; Jun KY; Kadayat TM; Shin S; Thapa Magar TB; Bist G; Shrestha A; Na Y; Kwon Y; Lee ES
    Eur J Med Chem; 2016 May; 113():228-45. PubMed ID: 26945111
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Identification of new halogen-containing 2,4-diphenyl indenopyridin-5-one derivative as a boosting agent for the anticancer responses of clinically available topoisomerase inhibitors.
    Hwang SY; Shrestha A; Park S; Bist G; Kunwar S; Kadayat TM; Jang H; Seo M; Sheen N; Kim S; Jeon KH; Lee ES; Kwon Y
    Eur J Med Chem; 2022 Jan; 227():113916. PubMed ID: 34678573
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.