BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

149 related articles for article (PubMed ID: 34542283)

  • 1. Rational Redesign of Enzyme via the Combination of Quantum Mechanics/Molecular Mechanics, Molecular Dynamics, and Structural Biology Study.
    Lin HY; Chen X; Dong J; Yang JF; Xiao H; Ye Y; Li LH; Zhan CG; Yang WC; Yang GF
    J Am Chem Soc; 2021 Sep; 143(38):15674-15687. PubMed ID: 34542283
    [TBL] [Abstract][Full Text] [Related]  

  • 2. 4-Hydroxyphenylpyruvate dioxygenase.
    Moran GR
    Arch Biochem Biophys; 2005 Jan; 433(1):117-28. PubMed ID: 15581571
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mechanism of benzylic hydroxylation by 4-hydroxymandelate synthase. A computational study.
    Wójcik A; Broclawik E; Siegbahn PE; Borowski T
    Biochemistry; 2012 Nov; 51(47):9570-80. PubMed ID: 23126679
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Free energy calculations elucidate substrate binding, gating mechanism, and tolerance-promoting mutations in herbicide target 4-hydroxyphenylpyruvate dioxygenase.
    Schindler CEM; Hollenbach E; Mietzner T; Schleifer KJ; Zacharias M
    Protein Sci; 2019 Jun; 28(6):1048-1058. PubMed ID: 30945368
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Functional role of residues involved in substrate binding of human 4-hydroxyphenylpyruvate dioxygenase.
    Huang CW; Hwang CC; Chang YL; Liu JT; Wu SP; Huang KL; Huang WM; Lee HJ
    Biochem J; 2021 Jun; 478(12):2201-2215. PubMed ID: 34047349
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Based on the Virtual Screening of Multiple Pharmacophores, Docking and Molecular Dynamics Simulation Approaches toward the Discovery of Novel HPPD Inhibitors.
    Fu Y; Ye T; Liu YX; Wang J; Ye F
    Int J Mol Sci; 2020 Aug; 21(15):. PubMed ID: 32756361
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structural basis for herbicidal inhibitor selectivity revealed by comparison of crystal structures of plant and mammalian 4-hydroxyphenylpyruvate dioxygenases.
    Yang C; Pflugrath JW; Camper DL; Foster ML; Pernich DJ; Walsh TA
    Biochemistry; 2004 Aug; 43(32):10414-23. PubMed ID: 15301540
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Molecular insights into the mechanism of 4-hydroxyphenylpyruvate dioxygenase inhibition: enzyme kinetics, X-ray crystallography and computational simulations.
    Lin HY; Yang JF; Wang DW; Hao GF; Dong JQ; Wang YX; Yang WC; Wu JW; Zhan CG; Yang GF
    FEBS J; 2019 Mar; 286(5):975-990. PubMed ID: 30632699
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Catalytic, noncatalytic, and inhibitory phenomena: kinetic analysis of (4-hydroxyphenyl)pyruvate dioxygenase from Arabidopsis thaliana.
    Purpero VM; Moran GR
    Biochemistry; 2006 May; 45(19):6044-55. PubMed ID: 16681377
    [TBL] [Abstract][Full Text] [Related]  

  • 10. 4-hydroxyphenylpyruvate dioxygenase catalysis: identification of catalytic residues and production of a hydroxylated intermediate shared with a structurally unrelated enzyme.
    Raspail C; Graindorge M; Moreau Y; Crouzy S; Lefèbvre B; Robin AY; Dumas R; Matringe M
    J Biol Chem; 2011 Jul; 286(29):26061-70. PubMed ID: 21613226
    [TBL] [Abstract][Full Text] [Related]  

  • 11. 4-Hydroxyphenylpyruvate Dioxygenase Inhibitors: From Chemical Biology to Agrochemicals.
    Ndikuryayo F; Moosavi B; Yang WC; Yang GF
    J Agric Food Chem; 2017 Oct; 65(39):8523-8537. PubMed ID: 28903556
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Role of the N-terminus in human 4-hydroxyphenylpyruvate dioxygenase activity.
    Feng AN; Huang CW; Lin CH; Chang YL; Ni MY; Lee HJ
    J Biochem; 2020 Mar; 167(3):315-322. PubMed ID: 31722428
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Structure-Guided Discovery of Silicon-Containing Subnanomolar Inhibitor of Hydroxyphenylpyruvate Dioxygenase as a Potential Herbicide.
    Qu RY; Nan JX; Yan YC; Chen Q; Ndikuryayo F; Wei XF; Yang WC; Lin HY; Yang GF
    J Agric Food Chem; 2021 Jan; 69(1):459-473. PubMed ID: 33395281
    [TBL] [Abstract][Full Text] [Related]  

  • 14. 3D Pharmacophore-Based Virtual Screening and Docking Approaches toward the Discovery of Novel HPPD Inhibitors.
    Fu Y; Sun YN; Yi KH; Li MQ; Cao HF; Li JZ; Ye F
    Molecules; 2017 Jun; 22(6):. PubMed ID: 28598377
    [No Abstract]   [Full Text] [Related]  

  • 15. Intermediate partitioning kinetic isotope effects for the NIH shift of 4-hydroxyphenylpyruvate dioxygenase and the hydroxylation reaction of hydroxymandelate synthase reveal mechanistic complexity.
    Shah DD; Conrad JA; Moran GR
    Biochemistry; 2013 Sep; 52(35):6097-107. PubMed ID: 23941465
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Crystal structure of Pseudomonas fluorescens 4-hydroxyphenylpyruvate dioxygenase: an enzyme involved in the tyrosine degradation pathway.
    Serre L; Sailland A; Sy D; Boudec P; Rolland A; Pebay-Peyroula E; Cohen-Addad C
    Structure; 1999 Aug; 7(8):977-88. PubMed ID: 10467142
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Pyrazole-Isoindoline-1,3-dione Hybrid: A Promising Scaffold for 4-Hydroxyphenylpyruvate Dioxygenase Inhibitors.
    He B; Dong J; Lin HY; Wang MY; Li XK; Zheng BF; Chen Q; Hao GF; Yang WC; Yang GF
    J Agric Food Chem; 2019 Oct; 67(39):10844-10852. PubMed ID: 31525997
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Insights into 4-hydroxyphenylpyruvate dioxygenase-inhibitor interactions from comparative structural biology.
    Lin HY; Dong J; Dong J; Yang WC; Yang GF
    Trends Biochem Sci; 2023 Jun; 48(6):568-584. PubMed ID: 36959016
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The different catalytic roles of the metal-binding ligands in human 4-hydroxyphenylpyruvate dioxygenase.
    Huang CW; Liu HC; Shen CP; Chen YT; Lee SJ; Lloyd MD; Lee HJ
    Biochem J; 2016 May; 473(9):1179-89. PubMed ID: 26936969
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Discovery of Subnanomolar Inhibitors of 4-Hydroxyphenylpyruvate Dioxygenase via Structure-Based Rational Design.
    Dong J; Dong J; Yu XH; Yan YC; Nan JX; Ye BQ; Yang WC; Lin HY; Yang GF
    J Agric Food Chem; 2023 Jan; 71(2):1170-1177. PubMed ID: 36599124
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.