These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

152 related articles for article (PubMed ID: 34542936)

  • 1. On the Weak Binding and Spectroscopic Signature of SARS-CoV-2 nsp14 Interaction with RNA.
    Hassan A; Sedenho GC; Vitale PAM; Oliviera MN; Crespilho FN
    Chembiochem; 2021 Dec; 22(24):3410-3413. PubMed ID: 34542936
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structure and dynamics of SARS-CoV-2 proofreading exoribonuclease ExoN.
    Moeller NH; Shi K; Demir Ö; Belica C; Banerjee S; Yin L; Durfee C; Amaro RE; Aihara H
    Proc Natl Acad Sci U S A; 2022 Mar; 119(9):. PubMed ID: 35165203
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The Enzymatic Activity of the nsp14 Exoribonuclease Is Critical for Replication of MERS-CoV and SARS-CoV-2.
    Ogando NS; Zevenhoven-Dobbe JC; van der Meer Y; Bredenbeek PJ; Posthuma CC; Snijder EJ
    J Virol; 2020 Nov; 94(23):. PubMed ID: 32938769
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Crystal structure of SARS-CoV-2 nsp10 bound to nsp14-ExoN domain reveals an exoribonuclease with both structural and functional integrity.
    Lin S; Chen H; Chen Z; Yang F; Ye F; Zheng Y; Yang J; Lin X; Sun H; Wang L; Wen A; Dong H; Xiao Q; Deng D; Cao Y; Lu G
    Nucleic Acids Res; 2021 May; 49(9):5382-5392. PubMed ID: 33956156
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Activation of the SARS-CoV-2 NSP14 3'-5' exoribonuclease by NSP10 and response to antiviral inhibitors.
    Riccio AA; Sullivan ED; Copeland WC
    J Biol Chem; 2022 Jan; 298(1):101518. PubMed ID: 34942146
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structure-function analysis of the nsp14 N7-guanine methyltransferase reveals an essential role in
    Ogando NS; El Kazzi P; Zevenhoven-Dobbe JC; Bontes BW; Decombe A; Posthuma CC; Thiel V; Canard B; Ferron F; Decroly E; Snijder EJ
    Proc Natl Acad Sci U S A; 2021 Dec; 118(49):. PubMed ID: 34845015
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Despite the odds: formation of the SARS-CoV-2 methylation complex.
    Matsuda A; Plewka J; Rawski M; Mourão A; Zajko W; Siebenmorgen T; Kresik L; Lis K; Jones AN; Pachota M; Karim A; Hartman K; Nirwal S; Sonani R; Chykunova Y; Minia I; Mak P; Landthaler M; Nowotny M; Dubin G; Sattler M; Suder P; Popowicz GM; Pyrć K; Czarna A
    Nucleic Acids Res; 2024 Jun; 52(11):6441-6458. PubMed ID: 38499483
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Development of a High-Throughput Screening Assay to Identify Inhibitors of the SARS-CoV-2 Guanine-N7-Methyltransferase Using RapidFire Mass Spectrometry.
    Pearson LA; Green CJ; Lin D; Petit AP; Gray DW; Cowling VH; Fordyce EAF
    SLAS Discov; 2021 Jul; 26(6):749-756. PubMed ID: 33724070
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Characterization of the SARS-CoV-2 ExoN (nsp14ExoN-nsp10) complex: implications for its role in viral genome stability and inhibitor identification.
    Baddock HT; Brolih S; Yosaatmadja Y; Ratnaweera M; Bielinski M; Swift LP; Cruz-Migoni A; Fan H; Keown JR; Walker AP; Morris GM; Grimes JM; Fodor E; Schofield CJ; Gileadi O; McHugh PJ
    Nucleic Acids Res; 2022 Feb; 50(3):1484-1500. PubMed ID: 35037045
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Reconstitution and functional characterization of SARS-CoV-2 proofreading complex.
    Ma Z; Pourfarjam Y; Kim IK
    Protein Expr Purif; 2021 Sep; 185():105894. PubMed ID: 33933612
    [TBL] [Abstract][Full Text] [Related]  

  • 11. SARS-CoV-2 Nsp14 mediates the effects of viral infection on the host cell transcriptome.
    Zaffagni M; Harris JM; Patop IL; Pamudurti NR; Nguyen S; Kadener S
    Elife; 2022 Mar; 11():. PubMed ID: 35293857
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Refolding of lid subdomain of SARS-CoV-2 nsp14 upon nsp10 interaction releases exonuclease activity.
    Czarna A; Plewka J; Kresik L; Matsuda A; Karim A; Robinson C; O'Byrne S; Cunningham F; Georgiou I; Wilk P; Pachota M; Popowicz G; Wyatt PG; Dubin G; Pyrć K
    Structure; 2022 Aug; 30(8):1050-1054.e2. PubMed ID: 35609600
    [TBL] [Abstract][Full Text] [Related]  

  • 13. SARS-CoV-2 nsp14 Exoribonuclease Removes the Natural Antiviral 3'-Deoxy-3',4'-didehydro-cytidine Nucleotide from RNA.
    Moeller NH; Passow KT; Harki DA; Aihara H
    Viruses; 2022 Aug; 14(8):. PubMed ID: 36016411
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Ritonavir may inhibit exoribonuclease activity of nsp14 from the SARS-CoV-2 virus and potentiate the activity of chain terminating drugs.
    Narayanan N; Nair DT
    Int J Biol Macromol; 2021 Jan; 168():272-278. PubMed ID: 33309661
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Label-Free Screening of SARS-CoV-2 NSP14 Exonuclease Activity Using SAMDI Mass Spectrometry.
    Scholle MD; Liu C; Deval J; Gurard-Levin ZA
    SLAS Discov; 2021 Jul; 26(6):766-774. PubMed ID: 33870746
    [TBL] [Abstract][Full Text] [Related]  

  • 16. SIRT5 is a proviral factor that interacts with SARS-CoV-2 Nsp14 protein.
    Walter M; Chen IP; Vallejo-Gracia A; Kim IJ; Bielska O; Lam VL; Hayashi JM; Cruz A; Shah S; Soveg FW; Gross JD; Krogan NJ; Jerome KR; Schilling B; Ott M; Verdin E
    PLoS Pathog; 2022 Sep; 18(9):e1010811. PubMed ID: 36095012
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The NSP14/NSP10 RNA repair complex as a Pan-coronavirus therapeutic target.
    Rona G; Zeke A; Miwatani-Minter B; de Vries M; Kaur R; Schinlever A; Garcia SF; Goldberg HV; Wang H; Hinds TR; Bailly F; Zheng N; Cotelle P; Desmaële D; Landau NR; Dittmann M; Pagano M
    Cell Death Differ; 2022 Feb; 29(2):285-292. PubMed ID: 34862481
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis of adenine dinucleosides SAM analogs as specific inhibitors of SARS-CoV nsp14 RNA cap guanine-N7-methyltransferase.
    Ahmed-Belkacem R; Sutto-Ortiz P; Guiraud M; Canard B; Vasseur JJ; Decroly E; Debart F
    Eur J Med Chem; 2020 Sep; 201():112557. PubMed ID: 32563813
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Opportunities and Challenges in Targeting the Proofreading Activity of SARS-CoV-2 Polymerase Complex.
    Deval J; Gurard-Levin ZA
    Molecules; 2022 May; 27(9):. PubMed ID: 35566268
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Crystal structures and fragment screening of SARS-CoV-2 NSP14 reveal details of exoribonuclease activation and mRNA capping and provide starting points for antiviral drug development.
    Imprachim N; Yosaatmadja Y; Newman JA
    Nucleic Acids Res; 2023 Jan; 51(1):475-487. PubMed ID: 36546776
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.