363 related articles for article (PubMed ID: 34544834)
1. Somatostatin-Positive Interneurons Contribute to Seizures in
Wengert ER; Miralles RM; Wedgwood KCA; Wagley PK; Strohm SM; Panchal PS; Idrissi AM; Wenker IC; Thompson JA; Gaykema RP; Patel MK
J Neurosci; 2021 Nov; 41(44):9257-9273. PubMed ID: 34544834
[No Abstract] [Full Text] [Related]
2. Aberrant Sodium Channel Currents and Hyperexcitability of Medial Entorhinal Cortex Neurons in a Mouse Model of
Ottolini M; Barker BS; Gaykema RP; Meisler MH; Patel MK
J Neurosci; 2017 Aug; 37(32):7643-7655. PubMed ID: 28676574
[No Abstract] [Full Text] [Related]
3. Prax330 reduces persistent and resurgent sodium channel currents and neuronal hyperexcitability of subiculum neurons in a mouse model of SCN8A epileptic encephalopathy.
Wengert ER; Saga AU; Panchal PS; Barker BS; Patel MK
Neuropharmacology; 2019 Nov; 158():107699. PubMed ID: 31278928
[TBL] [Abstract][Full Text] [Related]
4. Parvalbumin Interneuron Impairment Leads to Synaptic Transmission Deficits and Seizures in
Miralles RM; Boscia AR; Kittur S; Vundela SR; Wengert ER; Patel MK
bioRxiv; 2024 Mar; ():. PubMed ID: 38464208
[No Abstract] [Full Text] [Related]
5. The novel sodium channel modulator GS-458967 (GS967) is an effective treatment in a mouse model of SCN8A encephalopathy.
Baker EM; Thompson CH; Hawkins NA; Wagnon JL; Wengert ER; Patel MK; George AL; Meisler MH; Kearney JA
Epilepsia; 2018 Jun; 59(6):1166-1176. PubMed ID: 29782051
[TBL] [Abstract][Full Text] [Related]
6. Astrocyte reactivity in a mouse model of SCN8A epileptic encephalopathy.
Thompson JA; Miralles RM; Wengert ER; Wagley PK; Yu W; Wenker IC; Patel MK
Epilepsia Open; 2022 Jun; 7(2):280-292. PubMed ID: 34826216
[TBL] [Abstract][Full Text] [Related]
7. An Scn1a epilepsy mutation in Scn8a alters seizure susceptibility and behavior.
Makinson CD; Dutt K; Lin F; Papale LA; Shankar A; Barela AJ; Liu R; Goldin AL; Escayg A
Exp Neurol; 2016 Jan; 275 Pt 1(0 1):46-58. PubMed ID: 26410685
[TBL] [Abstract][Full Text] [Related]
8. Variant-specific changes in persistent or resurgent sodium current in SCN8A-related epilepsy patient-derived neurons.
Tidball AM; Lopez-Santiago LF; Yuan Y; Glenn TW; Margolis JL; Clayton Walker J; Kilbane EG; Miller CA; Martina Bebin E; Scott Perry M; Isom LL; Parent JM
Brain; 2020 Oct; 143(10):3025-3040. PubMed ID: 32968789
[TBL] [Abstract][Full Text] [Related]
9. Convulsive seizures and SUDEP in a mouse model of SCN8A epileptic encephalopathy.
Wagnon JL; Korn MJ; Parent R; Tarpey TA; Jones JM; Hammer MF; Murphy GG; Parent JM; Meisler MH
Hum Mol Genet; 2015 Jan; 24(2):506-15. PubMed ID: 25227913
[TBL] [Abstract][Full Text] [Related]
10. NBI-921352, a first-in-class, Na
Johnson JP; Focken T; Khakh K; Tari PK; Dube C; Goodchild SJ; Andrez JC; Bankar G; Bogucki D; Burford K; Chang E; Chowdhury S; Dean R; de Boer G; Decker S; Dehnhardt C; Feng M; Gong W; Grimwood M; Hasan A; Hussainkhel A; Jia Q; Lee S; Li J; Lin S; Lindgren A; Lofstrand V; Mezeyova J; Namdari R; Nelkenbrecher K; Shuart NG; Sojo L; Sun S; Taron M; Waldbrook M; Weeratunge D; Wesolowski S; Williams A; Wilson M; Xie Z; Yoo R; Young C; Zenova A; Zhang W; Cutts AJ; Sherrington RP; Pimstone SN; Winquist R; Cohen CJ; Empfield JR
Elife; 2022 Mar; 11():. PubMed ID: 35234610
[TBL] [Abstract][Full Text] [Related]
11. Gabra2 is a genetic modifier of Scn8a encephalopathy in the mouse.
Yu W; Hill SF; Xenakis JG; Pardo-Manuel de Villena F; Wagnon JL; Meisler MH
Epilepsia; 2020 Dec; 61(12):2847-2856. PubMed ID: 33140451
[TBL] [Abstract][Full Text] [Related]
12. Characterization of a de novo SCN8A mutation in a patient with epileptic encephalopathy.
de Kovel CG; Meisler MH; Brilstra EH; van Berkestijn FM; van 't Slot R; van Lieshout S; Nijman IJ; O'Brien JE; Hammer MF; Estacion M; Waxman SG; Dib-Hajj SD; Koeleman BP
Epilepsy Res; 2014 Nov; 108(9):1511-8. PubMed ID: 25239001
[TBL] [Abstract][Full Text] [Related]
13. Neuronal hyperexcitability in a mouse model of
Lopez-Santiago LF; Yuan Y; Wagnon JL; Hull JM; Frasier CR; O'Malley HA; Meisler MH; Isom LL
Proc Natl Acad Sci U S A; 2017 Feb; 114(9):2383-2388. PubMed ID: 28193882
[TBL] [Abstract][Full Text] [Related]
14. Genetic and clinical features of SCN8A developmental and epileptic encephalopathy.
Kim HJ; Yang D; Kim SH; Kim B; Kim HD; Lee JS; Choi JR; Lee ST; Kang HC
Epilepsy Res; 2019 Dec; 158():106222. PubMed ID: 31675620
[TBL] [Abstract][Full Text] [Related]
15. Prominent role of forebrain excitatory neurons in SCN8A encephalopathy.
Bunton-Stasyshyn RKA; Wagnon JL; Wengert ER; Barker BS; Faulkner A; Wagley PK; Bhatia K; Jones JM; Maniaci MR; Parent JM; Goodkin HP; Patel MK; Meisler MH
Brain; 2019 Feb; 142(2):362-375. PubMed ID: 30601941
[TBL] [Abstract][Full Text] [Related]
16. A novel de novo mutation of SCN8A (Nav1.6) with enhanced channel activation in a child with epileptic encephalopathy.
Estacion M; O'Brien JE; Conravey A; Hammer MF; Waxman SG; Dib-Hajj SD; Meisler MH
Neurobiol Dis; 2014 Sep; 69():117-23. PubMed ID: 24874546
[TBL] [Abstract][Full Text] [Related]
17. Clinical study of 19 patients with SCN8A-related epilepsy: Two modes of onset regarding EEG and seizures.
Denis J; Villeneuve N; Cacciagli P; Mignon-Ravix C; Lacoste C; Lefranc J; Napuri S; Damaj L; Villega F; Pedespan JM; Moutton S; Mignot C; Doummar D; Lion-François L; Gataullina S; Dulac O; Martin M; Gueden S; Lesca G; Julia S; Cances C; Journel H; Altuzarra C; Ben Zeev B; Afenjar A; Barth M; Villard L; Milh M
Epilepsia; 2019 May; 60(5):845-856. PubMed ID: 31026061
[TBL] [Abstract][Full Text] [Related]
18. The SCN8A encephalopathy mutation p.Ile1327Val displays elevated sensitivity to the anticonvulsant phenytoin.
Barker BS; Ottolini M; Wagnon JL; Hollander RM; Meisler MH; Patel MK
Epilepsia; 2016 Sep; 57(9):1458-66. PubMed ID: 27375106
[TBL] [Abstract][Full Text] [Related]
19. SCN8A mutations in Chinese patients with early onset epileptic encephalopathy and benign infantile seizures.
Wang J; Gao H; Bao X; Zhang Q; Li J; Wei L; Wu X; Chen Y; Yu S
BMC Med Genet; 2017 Sep; 18(1):104. PubMed ID: 28923014
[TBL] [Abstract][Full Text] [Related]
20. Role of the hippocampus in Nav1.6 (Scn8a) mediated seizure resistance.
Makinson CD; Tanaka BS; Lamar T; Goldin AL; Escayg A
Neurobiol Dis; 2014 Aug; 68():16-25. PubMed ID: 24704313
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
