BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

204 related articles for article (PubMed ID: 34544906)

  • 1. A2E-induced inflammation and angiogenesis in RPE cells
    Fontaine V; Fournié M; Monteiro E; Boumedine T; Balducci C; Guibout L; Latil M; Sahel JA; Veillet S; Dilda PJ; Lafont R; Camelo S
    Aging (Albany NY); 2021 Sep; 13(18):22040-22058. PubMed ID: 34544906
    [No Abstract]   [Full Text] [Related]  

  • 2. RAR Inhibitors Display Photo-Protective and Anti-Inflammatory Effects in A2E Stimulated RPE Cells In Vitro through Non-Specific Modulation of PPAR or RXR Transactivation.
    Fontaine V; Boumedine T; Monteiro E; Fournié M; Gersende G; Sahel JA; Picaud S; Veillet S; Lafont R; Latil M; Dilda PJ; Camelo S
    Int J Mol Sci; 2024 Mar; 25(5):. PubMed ID: 38474284
    [No Abstract]   [Full Text] [Related]  

  • 3. Norbixin Protects Retinal Pigmented Epithelium Cells and Photoreceptors against A2E-Mediated Phototoxicity In Vitro and In Vivo.
    Fontaine V; Monteiro E; Brazhnikova E; Lesage L; Balducci C; Guibout L; Feraille L; Elena PP; Sahel JA; Veillet S; Lafont R
    PLoS One; 2016; 11(12):e0167793. PubMed ID: 27992460
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Anti-Inflammatory Effects and Photo- and Neuro-Protective Properties of BIO203, a New Amide Conjugate of Norbixin, in Development for the Treatment of Age-Related Macular Degeneration (AMD).
    Fontaine V; Balducci C; Dinan L; Monteiro E; Boumedine T; Fournié M; Nguyen V; Guibout L; Clatot J; Latil M; Veillet S; Sahel JA; Lafont R; Dilda PJ; Camelo S
    Int J Mol Sci; 2023 Mar; 24(6):. PubMed ID: 36982372
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Systemic administration of the di-apocarotenoid norbixin (BIO201) is neuroprotective, preserves photoreceptor function and inhibits A2E and lipofuscin accumulation in animal models of age-related macular degeneration and Stargardt disease.
    Fontaine V; Monteiro E; Fournié M; Brazhnikova E; Boumedine T; Vidal C; Balducci C; Guibout L; Latil M; Dilda PJ; Veillet S; Sahel JA; Lafont R; Camelo S
    Aging (Albany NY); 2020 Apr; 12(7):6151-6171. PubMed ID: 32255762
    [TBL] [Abstract][Full Text] [Related]  

  • 6. DNA sequence variants in PPARGC1A, a gene encoding a coactivator of the ω-3 LCPUFA sensing PPAR-RXR transcription complex, are associated with NV AMD and AMD-associated loci in genes of complement and VEGF signaling pathways.
    SanGiovanni JP; Chen J; Sapieha P; Aderman CM; Stahl A; Clemons TE; Chew EY; Smith LE
    PLoS One; 2013; 8(1):e53155. PubMed ID: 23335958
    [TBL] [Abstract][Full Text] [Related]  

  • 7. PPARβ/δ selectively regulates phenotypic features of age-related macular degeneration.
    Choudhary M; Ding JD; Qi X; Boulton ME; Yao PL; Peters JM; Malek G
    Aging (Albany NY); 2016 Sep; 8(9):1952-1978. PubMed ID: 27622388
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Protective effects of retinoid x receptors on retina pigment epithelium cells.
    Ayala-Peña VB; Pilotti F; Volonté Y; Rotstein NP; Politi LE; German OL
    Biochim Biophys Acta; 2016 Jun; 1863(6 Pt A):1134-45. PubMed ID: 26883505
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A2E induces IL-1ß production in retinal pigment epithelial cells via the NLRP3 inflammasome.
    Anderson OA; Finkelstein A; Shima DT
    PLoS One; 2013; 8(6):e67263. PubMed ID: 23840644
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The peroxisome proliferator-activated receptor pan-agonist bezafibrate suppresses microvascular inflammatory responses of retinal endothelial cells and vascular endothelial growth factor production in retinal pigmented epithelial cells.
    Usui-Ouchi A; Ouchi Y; Ebihara N
    Int Immunopharmacol; 2017 Nov; 52():70-76. PubMed ID: 28866026
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Oxalomalate reduces expression and secretion of vascular endothelial growth factor in the retinal pigment epithelium and inhibits angiogenesis: Implications for age-related macular degeneration.
    Kim SH; Kim H; Ku HJ; Park JH; Cha H; Lee S; Lee JH; Park JW
    Redox Biol; 2016 Dec; 10():211-220. PubMed ID: 27810736
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Activation of retinoic X receptor and peroxisome proliferator-activated receptor-gamma inhibits nitric oxide and tumor necrosis factor-alpha production in rat Kupffer cells.
    Uchimura K; Nakamuta M; Enjoji M; Irie T; Sugimoto R; Muta T; Iwamoto H; Nawata H
    Hepatology; 2001 Jan; 33(1):91-9. PubMed ID: 11124825
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A2E, a component of lipofuscin, is pro-angiogenic in vivo.
    Iriyama A; Inoue Y; Takahashi H; Tamaki Y; Jang WD; Yanagi Y
    J Cell Physiol; 2009 Aug; 220(2):469-75. PubMed ID: 19418485
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Protective effect of autophagy on human retinal pigment epithelial cells against lipofuscin fluorophore A2E: implications for age-related macular degeneration.
    Zhang J; Bai Y; Huang L; Qi Y; Zhang Q; Li S; Wu Y; Li X
    Cell Death Dis; 2015 Nov; 6(11):e1972. PubMed ID: 26561782
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Peroxisome proliferator-activated receptors modulate proliferation and angiogenesis in human endometrial carcinoma.
    Nickkho-Amiry M; McVey R; Holland C
    Mol Cancer Res; 2012 Mar; 10(3):441-53. PubMed ID: 22205725
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Suppressive Effect of
    Kim DH; Choi YR; Shim J; Choi YS; Kim YT; Kim MK; Kim MJ
    Molecules; 2020 Apr; 25(7):. PubMed ID: 32283798
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A novel fluorescence-based assay for measuring A2E removal from human retinal pigment epithelial cells to screen for age-related macular degeneration inhibitors.
    Jin HL; Lee SC; Kwon YS; Choung SY; Jeong KW
    J Pharm Biomed Anal; 2016 Jan; 117():560-7. PubMed ID: 26604166
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Acid-Induced Intracellular Dissociation of β-Cyclodextrin-Threaded Polyrotaxanes Directed toward Attenuating Phototoxicity of Bisretinoids through Promoting Excretion.
    Tamura A; Ohashi M; Nishida K; Yui N
    Mol Pharm; 2017 Dec; 14(12):4714-4724. PubMed ID: 29120644
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Lipofuscin and N-retinylidene-N-retinylethanolamine (A2E) accumulate in retinal pigment epithelium in absence of light exposure: their origin is 11-cis-retinal.
    Boyer NP; Higbee D; Currin MB; Blakeley LR; Chen C; Ablonczy Z; Crouch RK; Koutalos Y
    J Biol Chem; 2012 Jun; 287(26):22276-86. PubMed ID: 22570475
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Toxic effects of A2E in human ARPE-19 cells were prevented by resveratrol: a potential nutritional bioactive for age-related macular degeneration treatment.
    Alaimo A; Di Santo MC; Domínguez Rubio AP; Chaufan G; García Liñares G; Pérez OE
    Arch Toxicol; 2020 Feb; 94(2):553-572. PubMed ID: 31792590
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.