BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

279 related articles for article (PubMed ID: 34555356)

  • 1. NSD2 dimethylation at H3K36 promotes lung adenocarcinoma pathogenesis.
    Sengupta D; Zeng L; Li Y; Hausmann S; Ghosh D; Yuan G; Nguyen TN; Lyu R; Caporicci M; Morales Benitez A; Coles GL; Kharchenko V; Czaban I; Azhibek D; Fischle W; Jaremko M; Wistuba II; Sage J; Jaremko Ł; Li W; Mazur PK; Gozani O
    Mol Cell; 2021 Nov; 81(21):4481-4492.e9. PubMed ID: 34555356
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structural basis of the regulation of the normal and oncogenic methylation of nucleosomal histone H3 Lys36 by NSD2.
    Sato K; Kumar A; Hamada K; Okada C; Oguni A; Machiyama A; Sakuraba S; Nishizawa T; Nureki O; Kono H; Ogata K; Sengoku T
    Nat Commun; 2021 Nov; 12(1):6605. PubMed ID: 34782608
    [TBL] [Abstract][Full Text] [Related]  

  • 3. NSD2 links dimethylation of histone H3 at lysine 36 to oncogenic programming.
    Kuo AJ; Cheung P; Chen K; Zee BM; Kioi M; Lauring J; Xi Y; Park BH; Shi X; Garcia BA; Li W; Gozani O
    Mol Cell; 2011 Nov; 44(4):609-20. PubMed ID: 22099308
    [TBL] [Abstract][Full Text] [Related]  

  • 4. NSD2 contributes to oncogenic RAS-driven transcription in lung cancer cells through long-range epigenetic activation.
    García-Carpizo V; Sarmentero J; Han B; Graña O; Ruiz-Llorente S; Pisano DG; Serrano M; Brooks HB; Campbell RM; Barrero MJ
    Sci Rep; 2016 Sep; 6():32952. PubMed ID: 27604143
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A PWWP Domain of Histone-Lysine N-Methyltransferase NSD2 Binds to Dimethylated Lys-36 of Histone H3 and Regulates NSD2 Function at Chromatin.
    Sankaran SM; Wilkinson AW; Elias JE; Gozani O
    J Biol Chem; 2016 Apr; 291(16):8465-74. PubMed ID: 26912663
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Reprogramming metabolism by histone methyltransferase NSD2 drives endocrine resistance via coordinated activation of pentose phosphate pathway enzymes.
    Wang J; Duan Z; Nugent Z; Zou JX; Borowsky AD; Zhang Y; Tepper CG; Li JJ; Fiehn O; Xu J; Kung HJ; Murphy LC; Chen HW
    Cancer Lett; 2016 Aug; 378(2):69-79. PubMed ID: 27164560
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Histone methyltransferase NSD2/MMSET mediates constitutive NF-κB signaling for cancer cell proliferation, survival, and tumor growth via a feed-forward loop.
    Yang P; Guo L; Duan ZJ; Tepper CG; Xue L; Chen X; Kung HJ; Gao AC; Zou JX; Chen HW
    Mol Cell Biol; 2012 Aug; 32(15):3121-31. PubMed ID: 22645312
    [TBL] [Abstract][Full Text] [Related]  

  • 8. NSD2 as a Promising Target in Hematological Disorders.
    Azagra A; Cobaleda C
    Int J Mol Sci; 2022 Sep; 23(19):. PubMed ID: 36232375
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Identification of histone methyltransferase NSD2 as an important oncogenic gene in colorectal cancer.
    Zhao LH; Li Q; Huang ZJ; Sun MX; Lu JJ; Zhang XH; Li G; Wu F
    Cell Death Dis; 2021 Oct; 12(11):974. PubMed ID: 34671018
    [TBL] [Abstract][Full Text] [Related]  

  • 10. SAM68 promotes tumorigenesis in lung adenocarcinoma by regulating metabolic conversion via PKM alternative splicing.
    Zhu S; Chen W; Wang J; Qi L; Pan H; Feng Z; Tian D
    Theranostics; 2021; 11(7):3359-3375. PubMed ID: 33537092
    [No Abstract]   [Full Text] [Related]  

  • 11. SMARCA2 Is a Novel Interactor of NSD2 and Regulates Prometastatic
    Chong PSY; Chooi JY; Lim JSL; Toh SHM; Tan TZ; Chng WJ
    Cancer Res; 2021 May; 81(9):2332-2344. PubMed ID: 33602783
    [TBL] [Abstract][Full Text] [Related]  

  • 12. FAM83H-AS1 is a noncoding oncogenic driver and therapeutic target of lung adenocarcinoma.
    Wang S; Han C; Liu T; Ma Z; Qiu M; Wang J; You Q; Zheng X; Xu W; Xia W; Xu Y; Hu J; Xu L; Yin R
    Clin Transl Med; 2021 Feb; 11(2):e316. PubMed ID: 33634993
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Transition state for the NSD2-catalyzed methylation of histone H3 lysine 36.
    Poulin MB; Schneck JL; Matico RE; McDevitt PJ; Huddleston MJ; Hou W; Johnson NW; Thrall SH; Meek TD; Schramm VL
    Proc Natl Acad Sci U S A; 2016 Feb; 113(5):1197-201. PubMed ID: 26787850
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Global chromatin profiling reveals NSD2 mutations in pediatric acute lymphoblastic leukemia.
    Jaffe JD; Wang Y; Chan HM; Zhang J; Huether R; Kryukov GV; Bhang HE; Taylor JE; Hu M; Englund NP; Yan F; Wang Z; Robert McDonald E; Wei L; Ma J; Easton J; Yu Z; deBeaumount R; Gibaja V; Venkatesan K; Schlegel R; Sellers WR; Keen N; Liu J; Caponigro G; Barretina J; Cooke VG; Mullighan C; Carr SA; Downing JR; Garraway LA; Stegmeier F
    Nat Genet; 2013 Nov; 45(11):1386-91. PubMed ID: 24076604
    [TBL] [Abstract][Full Text] [Related]  

  • 15. ISWI chromatin remodeling complexes recruit NSD2 and H3K36me2 in pericentromeric heterochromatin.
    Goto N; Suke K; Yonezawa N; Nishihara H; Handa T; Sato Y; Kujirai T; Kurumizaka H; Yamagata K; Kimura H
    J Cell Biol; 2024 Aug; 223(8):. PubMed ID: 38709169
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Molecular basis of nucleosomal H3K36 methylation by NSD methyltransferases.
    Li W; Tian W; Yuan G; Deng P; Sengupta D; Cheng Z; Cao Y; Ren J; Qin Y; Zhou Y; Jia Y; Gozani O; Patel DJ; Wang Z
    Nature; 2021 Feb; 590(7846):498-503. PubMed ID: 33361816
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Elevated NSD3 histone methylation activity drives squamous cell lung cancer.
    Yuan G; Flores NM; Hausmann S; Lofgren SM; Kharchenko V; Angulo-Ibanez M; Sengupta D; Lu X; Czaban I; Azhibek D; Vicent S; Fischle W; Jaremko M; Fang B; Wistuba II; Chua KF; Roth JA; Minna JD; Shao NY; Jaremko Ł; Mazur PK; Gozani O
    Nature; 2021 Feb; 590(7846):504-508. PubMed ID: 33536620
    [TBL] [Abstract][Full Text] [Related]  

  • 18. WHSC1/NSD2 regulates immune infiltration in prostate cancer.
    Want MY; Tsuji T; Singh PK; Thorne JL; Matsuzaki J; Karasik E; Gillard B; Cortes Gomez E; Koya RC; Lugade A; Odunsi K; Battaglia S
    J Immunother Cancer; 2021 Feb; 9(2):. PubMed ID: 33589522
    [TBL] [Abstract][Full Text] [Related]  

  • 19. In vitro histone lysine methylation by NSD1, NSD2/MMSET/WHSC1 and NSD3/WHSC1L.
    Morishita M; Mevius D; di Luccio E
    BMC Struct Biol; 2014 Dec; 14():25. PubMed ID: 25494638
    [TBL] [Abstract][Full Text] [Related]  

  • 20. NSD2 inhibition suppresses metastasis in cervical cancer by promoting TGF-β/TGF-βRI/SMADs signaling.
    Zhu L; Yu CL; Zheng Y
    Biochem Biophys Res Commun; 2019 Nov; 519(3):489-496. PubMed ID: 31526565
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.