237 related articles for article (PubMed ID: 34556870)
1. Molecular basis of human ATM kinase inhibition.
Stakyte K; Rotheneder M; Lammens K; Bartho JD; Grädler U; Fuchß T; Pehl U; Alt A; van de Logt E; Hopfner KP
Nat Struct Mol Biol; 2021 Oct; 28(10):789-798. PubMed ID: 34556870
[TBL] [Abstract][Full Text] [Related]
2. Identification and characterization of a novel and specific inhibitor of the ataxia-telangiectasia mutated kinase ATM.
Hickson I; Zhao Y; Richardson CJ; Green SJ; Martin NM; Orr AI; Reaper PM; Jackson SP; Curtin NJ; Smith GC
Cancer Res; 2004 Dec; 64(24):9152-9. PubMed ID: 15604286
[TBL] [Abstract][Full Text] [Related]
3. Near-Complete Structure and Model of Tel1ATM from Chaetomium thermophilum Reveals a Robust Autoinhibited ATP State.
Jansma M; Linke-Winnebeck C; Eustermann S; Lammens K; Kostrewa D; Stakyte K; Litz C; Kessler B; Hopfner KP
Structure; 2020 Jan; 28(1):83-95.e5. PubMed ID: 31740028
[TBL] [Abstract][Full Text] [Related]
4. Structure of the intact ATM/Tel1 kinase.
Wang X; Chu H; Lv M; Zhang Z; Qiu S; Liu H; Shen X; Wang W; Cai G
Nat Commun; 2016 May; 7():11655. PubMed ID: 27229179
[TBL] [Abstract][Full Text] [Related]
5. Structural insights into the activation of ATM kinase.
Xiao J; Liu M; Qi Y; Chaban Y; Gao C; Pan B; Tian Y; Yu Z; Li J; Zhang P; Xu Y
Cell Res; 2019 Aug; 29(8):683-685. PubMed ID: 31320732
[No Abstract] [Full Text] [Related]
6. Structure of the human dimeric ATM kinase.
Lau WC; Li Y; Liu Z; Gao Y; Zhang Q; Huen MS
Cell Cycle; 2016; 15(8):1117-24. PubMed ID: 27097373
[TBL] [Abstract][Full Text] [Related]
7. Improved ATM kinase inhibitor KU-60019 radiosensitizes glioma cells, compromises insulin, AKT and ERK prosurvival signaling, and inhibits migration and invasion.
Golding SE; Rosenberg E; Valerie N; Hussaini I; Frigerio M; Cockcroft XF; Chong WY; Hummersone M; Rigoreau L; Menear KA; O'Connor MJ; Povirk LF; van Meter T; Valerie K
Mol Cancer Ther; 2009 Oct; 8(10):2894-902. PubMed ID: 19808981
[TBL] [Abstract][Full Text] [Related]
8. Structures and regulations of ATM and ATR, master kinases in genome integrity.
Williams RM; Yates LA; Zhang X
Curr Opin Struct Biol; 2020 Apr; 61():98-105. PubMed ID: 31924595
[TBL] [Abstract][Full Text] [Related]
9. Structure of the human ATM kinase and mechanism of Nbs1 binding.
Warren C; Pavletich NP
Elife; 2022 Jan; 11():. PubMed ID: 35076389
[TBL] [Abstract][Full Text] [Related]
10. The development of ataxia telangiectasia mutated kinase inhibitors.
Andrs M; Korabecny J; Nepovimova E; Jun D; Hodny Z; Moravcova S; Hanzlikova H; Kuca K
Mini Rev Med Chem; 2014; 14(10):805-11. PubMed ID: 25138084
[TBL] [Abstract][Full Text] [Related]
11. Depletion of ATR selectively sensitizes ATM-deficient human mammary epithelial cells to ionizing radiation and DNA-damaging agents.
Cui Y; Palii SS; Innes CL; Paules RS
Cell Cycle; 2014; 13(22):3541-50. PubMed ID: 25483091
[TBL] [Abstract][Full Text] [Related]
12. Hsp90α regulates ATM and NBN functions in sensing and repair of DNA double-strand breaks.
Pennisi R; Antoccia A; Leone S; Ascenzi P; di Masi A
FEBS J; 2017 Aug; 284(15):2378-2395. PubMed ID: 28631426
[TBL] [Abstract][Full Text] [Related]
13. Inhibition of ataxia telangiectasia mutated (ATM) kinase suppresses herpes simplex virus type 1 (HSV-1) keratitis.
Alekseev O; Donovan K; Azizkhan-Clifford J
Invest Ophthalmol Vis Sci; 2014 Feb; 55(2):706-15. PubMed ID: 24370835
[TBL] [Abstract][Full Text] [Related]
14. Structures of closed and open conformations of dimeric human ATM.
Baretić D; Pollard HK; Fisher DI; Johnson CM; Santhanam B; Truman CM; Kouba T; Fersht AR; Phillips C; Williams RL
Sci Adv; 2017 May; 3(5):e1700933. PubMed ID: 28508083
[TBL] [Abstract][Full Text] [Related]
15. ATM Mutations in Cancer: Therapeutic Implications.
Choi M; Kipps T; Kurzrock R
Mol Cancer Ther; 2016 Aug; 15(8):1781-91. PubMed ID: 27413114
[TBL] [Abstract][Full Text] [Related]
16. Feedback regulation of methyl methanesulfonate and ultraviolet-sensitive gene clone 81 via ATM/Chk2 pathway contributes to the resistance of MCF-7 breast cancer cells to cisplatin.
Lv J; Qian Y; Ni X; Xu X; Dong X
Tumour Biol; 2017 Mar; 39(3):1010428317694307. PubMed ID: 28347251
[TBL] [Abstract][Full Text] [Related]
17. A New Class of Selective ATM Inhibitors as Combination Partners of DNA Double-Strand Break Inducing Cancer Therapies.
Zimmermann A; Zenke FT; Chiu LY; Dahmen H; Pehl U; Fuchss T; Grombacher T; Blume B; Vassilev LT; Blaukat A
Mol Cancer Ther; 2022 Jun; 21(6):859-870. PubMed ID: 35405736
[TBL] [Abstract][Full Text] [Related]
18. The orally active and bioavailable ATR kinase inhibitor AZD6738 potentiates the anti-tumor effects of cisplatin to resolve ATM-deficient non-small cell lung cancer in vivo.
Vendetti FP; Lau A; Schamus S; Conrads TP; O'Connor MJ; Bakkenist CJ
Oncotarget; 2015 Dec; 6(42):44289-305. PubMed ID: 26517239
[TBL] [Abstract][Full Text] [Related]
19. Sensors and Inhibitors for the Detection of Ataxia Telangiectasia Mutated (ATM) Protein Kinase.
Huang C; Filippone NR; Reiner T; Roberts S
Mol Pharm; 2021 Jul; 18(7):2470-2481. PubMed ID: 34125542
[TBL] [Abstract][Full Text] [Related]
20. Studies of ATM Kinase Activity Using Engineered ATM Sensitive to ATP Analogues (ATM-AS).
Enari M; Matsushima-Hibiya Y; Miyazaki M; Otomo R
Methods Mol Biol; 2017; 1599():145-156. PubMed ID: 28477117
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]