164 related articles for article (PubMed ID: 34560000)
1. iPSC culture expansion selects against putatively actionable mutations in the mitochondrial genome.
Kosanke M; Davenport C; Szepes M; Wiehlmann L; Kohrn T; Dorda M; Gruber J; Menge K; Sievert M; Melchert A; Gruh I; Göhring G; Martin U
Stem Cell Reports; 2021 Oct; 16(10):2488-2502. PubMed ID: 34560000
[TBL] [Abstract][Full Text] [Related]
2. Disease-causing mitochondrial heteroplasmy segregated within induced pluripotent stem cell clones derived from a patient with MELAS.
Folmes CD; Martinez-Fernandez A; Perales-Clemente E; Li X; McDonald A; Oglesbee D; Hrstka SC; Perez-Terzic C; Terzic A; Nelson TJ
Stem Cells; 2013 Jul; 31(7):1298-308. PubMed ID: 23553816
[TBL] [Abstract][Full Text] [Related]
3. Cell reprogramming shapes the mitochondrial DNA landscape.
Wei W; Gaffney DJ; Chinnery PF
Nat Commun; 2021 Sep; 12(1):5241. PubMed ID: 34475388
[TBL] [Abstract][Full Text] [Related]
4. Natural underlying mtDNA heteroplasmy as a potential source of intra-person hiPSC variability.
Perales-Clemente E; Cook AN; Evans JM; Roellinger S; Secreto F; Emmanuele V; Oglesbee D; Mootha VK; Hirano M; Schon EA; Terzic A; Nelson TJ
EMBO J; 2016 Sep; 35(18):1979-90. PubMed ID: 27436875
[TBL] [Abstract][Full Text] [Related]
5. Human induced pluripotent stem cells harbor homoplasmic and heteroplasmic mitochondrial DNA mutations while maintaining human embryonic stem cell-like metabolic reprogramming.
Prigione A; Lichtner B; Kuhl H; Struys EA; Wamelink M; Lehrach H; Ralser M; Timmermann B; Adjaye J
Stem Cells; 2011 Sep; 29(9):1338-48. PubMed ID: 21732474
[TBL] [Abstract][Full Text] [Related]
6. Mitochondrial DNA Dynamics in Reprogramming to Pluripotency.
Sercel AJ; Carlson NM; Patananan AN; Teitell MA
Trends Cell Biol; 2021 Apr; 31(4):311-323. PubMed ID: 33422359
[TBL] [Abstract][Full Text] [Related]
7. Generation and Characterization of Induced Pluripotent Stem Cells from Patients with mtDNA Mutations.
Hämäläinen RH; Suomalainen A
Methods Mol Biol; 2016; 1353():65-75. PubMed ID: 26187202
[TBL] [Abstract][Full Text] [Related]
8. Somatic cells with a heavy mitochondrial DNA mutational load render induced pluripotent stem cells with distinct differentiation defects.
Wahlestedt M; Ameur A; Moraghebi R; Norddahl GL; Sten G; Woods NB; Bryder D
Stem Cells; 2014 May; 32(5):1173-82. PubMed ID: 24446123
[TBL] [Abstract][Full Text] [Related]
9. Concise Review: Heteroplasmic Mitochondrial DNA Mutations and Mitochondrial Diseases: Toward iPSC-Based Disease Modeling, Drug Discovery, and Regenerative Therapeutics.
Hatakeyama H; Goto Y
Stem Cells; 2016 Apr; 34(4):801-8. PubMed ID: 26850516
[TBL] [Abstract][Full Text] [Related]
10. Gaining Insight into Mitochondrial Genetic Variation and Downstream Pathophysiology: What Can i(PSCs) Do?
Moreira JD; Gopal DM; Kotton DN; Fetterman JL
Genes (Basel); 2021 Oct; 12(11):. PubMed ID: 34828274
[TBL] [Abstract][Full Text] [Related]
11. The relevance of mitochondrial DNA variants fluctuation during reprogramming and neuronal differentiation of human iPSCs.
Palombo F; Peron C; Caporali L; Iannielli A; Maresca A; Di Meo I; Fiorini C; Segnali A; Sciacca FL; Rizzo A; Levi S; Suomalainen A; Prigione A; Broccoli V; Carelli V; Tiranti V
Stem Cell Reports; 2021 Aug; 16(8):1953-1967. PubMed ID: 34329598
[TBL] [Abstract][Full Text] [Related]
12. Mitochondrial genome mutations and neuronal dysfunction of induced pluripotent stem cells derived from patients with Alzheimer's disease.
Lee Y; Kim M; Lee M; So S; Kang SS; Choi J; Kim D; Heo H; Lee SS; Park HR; Ko JJ; Song J; Kang E
Cell Prolif; 2022 Jul; 55(7):e13274. PubMed ID: 35698260
[TBL] [Abstract][Full Text] [Related]
13. Mitochondrial DNA mutations in iPS cells: mtDNA integrity as standard iPSC selection criteria?
Hämäläinen RH
EMBO J; 2016 Sep; 35(18):1960-2. PubMed ID: 27469999
[TBL] [Abstract][Full Text] [Related]
14. Targeted elimination of mutant mitochondrial DNA in MELAS-iPSCs by mitoTALENs.
Yang Y; Wu H; Kang X; Liang Y; Lan T; Li T; Tan T; Peng J; Zhang Q; An G; Liu Y; Yu Q; Ma Z; Lian Y; Soh BS; Chen Q; Liu P; Chen Y; Sun X; Li R; Zhen X; Liu P; Yu Y; Li X; Fan Y
Protein Cell; 2018 Mar; 9(3):283-297. PubMed ID: 29318513
[TBL] [Abstract][Full Text] [Related]
15. Single-cell individual full-length mtDNA sequencing by iMiGseq uncovers unexpected heteroplasmy shifts in mtDNA editing.
Bi C; Wang L; Fan Y; Yuan B; Ramos-Mandujano G; Zhang Y; Alsolami S; Zhou X; Wang J; Shao Y; Reddy P; Zhang PY; Huang Y; Yu Y; Izpisua Belmonte JC; Li M
Nucleic Acids Res; 2023 May; 51(8):e48. PubMed ID: 36999592
[TBL] [Abstract][Full Text] [Related]
16. Reprogramming enriches for somatic cell clones with small-scale mutations in cancer-associated genes.
Kosanke M; Osetek K; Haase A; Wiehlmann L; Davenport C; Schwarzer A; Adams F; Kleppa MJ; Schambach A; Merkert S; Wunderlich S; Menke S; Dorda M; Martin U
Mol Ther; 2021 Aug; 29(8):2535-2553. PubMed ID: 33831558
[TBL] [Abstract][Full Text] [Related]
17. Selection of iPSCs without mtDNA deletion for autologous cell therapy in a patient with Pearson syndrome.
Lee Y; Han J; Hwang SB; Kang SS; Son HB; Jin C; Kim JE; Lee BH; Kang E
BMB Rep; 2023 Aug; 56(8):463-468. PubMed ID: 37156631
[TBL] [Abstract][Full Text] [Related]
18. Mitochondrial respiratory dysfunction caused by a heteroplasmic mitochondrial DNA mutation blocks cellular reprogramming.
Yokota M; Hatakeyama H; Okabe S; Ono Y; Goto Y
Hum Mol Genet; 2015 Aug; 24(16):4698-709. PubMed ID: 26025377
[TBL] [Abstract][Full Text] [Related]
19. mRNA Reprogramming of T8993G Leigh's Syndrome Fibroblast Cells to Create Induced Pluripotent Stem Cell Models for Mitochondrial Disorders.
Grace HE; Galdun P; Lesnefsky EJ; West FD; Iyer S
Stem Cells Dev; 2019 Jul; 28(13):846-859. PubMed ID: 31017045
[TBL] [Abstract][Full Text] [Related]
20. Induced Pluripotent Stem Cells: Advances in the Quest for Genetic Stability during Reprogramming Process.
Turinetto V; Orlando L; Giachino C
Int J Mol Sci; 2017 Sep; 18(9):. PubMed ID: 28902128
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
