161 related articles for article (PubMed ID: 34560580)
1. Aromatic and aliphatic residues of the disordered region of TDP-43 are on a fast track for self-assembly.
Laurents DV; Stuani C; Pantoja-Uceda D; Buratti E; Mompeán M
Biochem Biophys Res Commun; 2021 Nov; 578():110-114. PubMed ID: 34560580
[TBL] [Abstract][Full Text] [Related]
2. TAR DNA-binding protein 43 (TDP-43) liquid-liquid phase separation is mediated by just a few aromatic residues.
Li HR; Chiang WC; Chou PC; Wang WJ; Huang JR
J Biol Chem; 2018 Apr; 293(16):6090-6098. PubMed ID: 29511089
[TBL] [Abstract][Full Text] [Related]
3. Prion-like C-Terminal Domain of TDP-43 and α-Synuclein Interact Synergistically to Generate Neurotoxic Hybrid Fibrils.
Dhakal S; Wyant CE; George HE; Morgan SE; Rangachari V
J Mol Biol; 2021 May; 433(10):166953. PubMed ID: 33771571
[TBL] [Abstract][Full Text] [Related]
4. The amyloidogenicity of a C-terminal region of TDP-43 implicated in Amyotrophic Lateral Sclerosis can be affected by anions, acetylation and homodimerization.
Prasad A; Sivalingam V; Bharathi V; Girdhar A; Patel BK
Biochimie; 2018 Jul; 150():76-87. PubMed ID: 29751083
[TBL] [Abstract][Full Text] [Related]
5. Computational insights into mechanism of AIM4-mediated inhibition of aggregation of TDP-43 protein implicated in ALS and evidence for in vitro inhibition of liquid-liquid phase separation (LLPS) of TDP-43
Girdhar A; Bharathi V; Tiwari VR; Abhishek S; Deeksha W; Mahawar US; Raju G; Singh SK; Prabusankar G; Rajakumara E; Patel BK
Int J Biol Macromol; 2020 Mar; 147():117-130. PubMed ID: 31917988
[TBL] [Abstract][Full Text] [Related]
6. ALS-Causing Mutations Significantly Perturb the Self-Assembly and Interaction with Nucleic Acid of the Intrinsically Disordered Prion-Like Domain of TDP-43.
Lim L; Wei Y; Lu Y; Song J
PLoS Biol; 2016 Jan; 14(1):e1002338. PubMed ID: 26735904
[TBL] [Abstract][Full Text] [Related]
7. The physical forces mediating self-association and phase-separation in the C-terminal domain of TDP-43.
Li HR; Chen TC; Hsiao CL; Shi L; Chou CY; Huang JR
Biochim Biophys Acta Proteins Proteom; 2018 Feb; 1866(2):214-223. PubMed ID: 28988034
[TBL] [Abstract][Full Text] [Related]
8. Zn
Preethi S; Bharathi V; Patel BK
Int J Biol Macromol; 2021 Apr; 176():186-200. PubMed ID: 33577819
[TBL] [Abstract][Full Text] [Related]
9. Inter-domain interactions of TDP-43 as decoded by NMR.
Wei Y; Lim L; Wang L; Song J
Biochem Biophys Res Commun; 2016 Apr; 473(2):614-9. PubMed ID: 27040765
[TBL] [Abstract][Full Text] [Related]
10. Solid-State NMR Reveals the Structural Transformation of the TDP-43 Amyloidogenic Region upon Fibrillation.
Zhuo XF; Wang J; Zhang J; Jiang LL; Hu HY; Lu JX
J Am Chem Soc; 2020 Feb; 142(7):3412-3421. PubMed ID: 32003979
[TBL] [Abstract][Full Text] [Related]
11. Granulins modulate liquid-liquid phase separation and aggregation of the prion-like C-terminal domain of the neurodegeneration-associated protein TDP-43.
Bhopatkar AA; Uversky VN; Rangachari V
J Biol Chem; 2020 Feb; 295(8):2506-2519. PubMed ID: 31911437
[TBL] [Abstract][Full Text] [Related]
12. The Folding and Aggregation Energy Landscapes of Tethered RRM Domains of Human TDP-43 Are Coupled via a Metastable Molten Globule-like Oligomer.
Pillai M; Jha SK
Biochemistry; 2019 Feb; 58(6):608-620. PubMed ID: 30520297
[TBL] [Abstract][Full Text] [Related]
13. Molecular mechanism of the inhibition of TDP-43 amyloidogenesis by QBP1.
Mompeán M; Ramírez de Mingo D; Hervás R; Fernández-Ramírez MDC; Carrión-Vázquez M; Laurents DV
Arch Biochem Biophys; 2019 Oct; 675():108113. PubMed ID: 31568752
[TBL] [Abstract][Full Text] [Related]
14. Aberrant assembly of RNA recognition motif 1 links to pathogenic conversion of TAR DNA-binding protein of 43 kDa (TDP-43).
Shodai A; Morimura T; Ido A; Uchida T; Ayaki T; Takahashi R; Kitazawa S; Suzuki S; Shirouzu M; Kigawa T; Muto Y; Yokoyama S; Takahashi R; Kitahara R; Ito H; Fujiwara N; Urushitani M
J Biol Chem; 2013 May; 288(21):14886-905. PubMed ID: 23558684
[TBL] [Abstract][Full Text] [Related]
15. A synergy between site-specific and transient interactions drives the phase separation of a disordered, low-complexity domain.
Mohanty P; Shenoy J; Rizuan A; Mercado-Ortiz JF; Fawzi NL; Mittal J
Proc Natl Acad Sci U S A; 2023 Aug; 120(34):e2305625120. PubMed ID: 37579155
[TBL] [Abstract][Full Text] [Related]
16. Review: Prion-like mechanisms of transactive response DNA binding protein of 43 kDa (TDP-43) in amyotrophic lateral sclerosis (ALS).
Smethurst P; Sidle KC; Hardy J
Neuropathol Appl Neurobiol; 2015 Aug; 41(5):578-97. PubMed ID: 25487060
[TBL] [Abstract][Full Text] [Related]
17. Implications of the prion-related Q/N domains in TDP-43 and FUS.
Udan M; Baloh RH
Prion; 2011; 5(1):1-5. PubMed ID: 21135580
[TBL] [Abstract][Full Text] [Related]
18. Prion-like nuclear aggregation of TDP-43 during heat shock is regulated by HSP40/70 chaperones.
Udan-Johns M; Bengoechea R; Bell S; Shao J; Diamond MI; True HL; Weihl CC; Baloh RH
Hum Mol Genet; 2014 Jan; 23(1):157-70. PubMed ID: 23962724
[TBL] [Abstract][Full Text] [Related]
19. Induction of amyloid fibrils by the C-terminal fragments of TDP-43 in amyotrophic lateral sclerosis.
Chen AK; Lin RY; Hsieh EZ; Tu PH; Chen RP; Liao TY; Chen W; Wang CH; Huang JJ
J Am Chem Soc; 2010 Feb; 132(4):1186-7. PubMed ID: 20055380
[TBL] [Abstract][Full Text] [Related]
20. ALS Mutations Disrupt Phase Separation Mediated by α-Helical Structure in the TDP-43 Low-Complexity C-Terminal Domain.
Conicella AE; Zerze GH; Mittal J; Fawzi NL
Structure; 2016 Sep; 24(9):1537-49. PubMed ID: 27545621
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
