313 related articles for article (PubMed ID: 34562654)
1. Persistent mTORC1 activation via Depdc5 deletion results in spontaneous hepatocellular carcinoma but does not exacerbate carcinogen- and high-fat diet-induced hepatic carcinogenesis in mice.
Xu L; Yang C; Wang J; Li Z; Huang R; Ma H; Ma J; Wang Q; Xiong X
Biochem Biophys Res Commun; 2021 Nov; 578():142-149. PubMed ID: 34562654
[TBL] [Abstract][Full Text] [Related]
2. Depdc5 deficiency exacerbates alcohol-induced hepatic steatosis via suppression of PPARα pathway.
Xu L; Zhang X; Xin Y; Ma J; Yang C; Zhang X; Hou G; Dong XC; Sun Z; Xiong X; Cao X
Cell Death Dis; 2021 Jul; 12(7):710. PubMed ID: 34267188
[TBL] [Abstract][Full Text] [Related]
3. Liver damage, inflammation, and enhanced tumorigenesis after persistent mTORC1 inhibition.
Umemura A; Park EJ; Taniguchi K; Lee JH; Shalapour S; Valasek MA; Aghajan M; Nakagawa H; Seki E; Hall MN; Karin M
Cell Metab; 2014 Jul; 20(1):133-44. PubMed ID: 24910242
[TBL] [Abstract][Full Text] [Related]
4. Adipocyte-specific deletion of Depdc5 exacerbates insulin resistance and adipose tissue inflammation in mice.
Zhang J; Shi Y; Yang C; Sun B; Ma H; Huang R; Li Z; Wang M; Wang Q; Ma J; Xiong X
Biochem Biophys Res Commun; 2021 Sep; 569():118-124. PubMed ID: 34243067
[TBL] [Abstract][Full Text] [Related]
5. High-saturate-fat diet delays initiation of diethylnitrosamine-induced hepatocellular carcinoma.
Duan XY; Pan Q; Yan SY; Ding WJ; Fan JG; Qiao L
BMC Gastroenterol; 2014 Nov; 14():195. PubMed ID: 25410681
[TBL] [Abstract][Full Text] [Related]
6. Lycopene metabolite, apo-10'-lycopenoic acid, inhibits diethylnitrosamine-initiated, high fat diet-promoted hepatic inflammation and tumorigenesis in mice.
Ip BC; Hu KQ; Liu C; Smith DE; Obin MS; Ausman LM; Wang XD
Cancer Prev Res (Phila); 2013 Dec; 6(12):1304-16. PubMed ID: 24085778
[TBL] [Abstract][Full Text] [Related]
7. Phosphorylation of DEPDC5, a component of the GATOR1 complex, releases inhibition of mTORC1 and promotes tumor growth.
Padi SKR; Singh N; Bearss JJ; Olive V; Song JH; Cardó-Vila M; Kraft AS; Okumura K
Proc Natl Acad Sci U S A; 2019 Oct; 116(41):20505-20510. PubMed ID: 31548394
[TBL] [Abstract][Full Text] [Related]
8. The Adenosine Monophosphate (AMP) Analog, 5-Aminoimidazole-4-Carboxamide Ribonucleotide (AICAR) Inhibits Hepatosteatosis and Liver Tumorigenesis in a High-Fat Diet Murine Model Treated with Diethylnitrosamine (DEN).
Gao J; Xiong R; Xiong D; Zhao W; Zhang S; Yin T; Zhang X; Jiang G; Yin Z
Med Sci Monit; 2018 Nov; 24():8533-8543. PubMed ID: 30474622
[TBL] [Abstract][Full Text] [Related]
9. RNA helicase DEAD-box protein 5 alleviates nonalcoholic steatohepatitis progression via tethering TSC complex and suppressing mTORC1 signaling.
Zhang Y; Ye S; Lu W; Zhong J; Leng Y; Yang T; Luo J; Xu W; Zhang H; Kong L
Hepatology; 2023 May; 77(5):1670-1687. PubMed ID: 35796622
[TBL] [Abstract][Full Text] [Related]
10. Timp3 deficiency affects the progression of DEN-related hepatocellular carcinoma during diet-induced obesity in mice.
Casagrande V; Mauriello A; Anemona L; Mavilio M; Iuliani G; De Angelis L; D'Onofrio M; Arisi I; Federici M; Menghini R
Acta Diabetol; 2019 Dec; 56(12):1265-1274. PubMed ID: 31292722
[TBL] [Abstract][Full Text] [Related]
11. TREM-2 defends the liver against hepatocellular carcinoma through multifactorial protective mechanisms.
Esparza-Baquer A; Labiano I; Sharif O; Agirre-Lizaso A; Oakley F; Rodrigues PM; Zhuravleva E; O'Rourke CJ; Hijona E; Jimenez-Agüero R; Riaño I; Landa A; La Casta A; Zaki MYW; Munoz-Garrido P; Azkargorta M; Elortza F; Vogel A; Schabbauer G; Aspichueta P; Andersen JB; Knapp S; Mann DA; Bujanda L; Banales JM; Perugorria MJ
Gut; 2021 Jul; 70(7):1345-1361. PubMed ID: 32907830
[TBL] [Abstract][Full Text] [Related]
12. High-refined-carbohydrate and high-fat diets induce comparable hepatic tumorigenesis in male mice.
Ip BC; Liu C; Smith DE; Ausman LM; Wang XD
J Nutr; 2014 May; 144(5):647-53. PubMed ID: 24647392
[TBL] [Abstract][Full Text] [Related]
13. Chronic activation of mTOR complex 1 is sufficient to cause hepatocellular carcinoma in mice.
Menon S; Yecies JL; Zhang HH; Howell JJ; Nicholatos J; Harputlugil E; Bronson RT; Kwiatkowski DJ; Manning BD
Sci Signal; 2012 Mar; 5(217):ra24. PubMed ID: 22457330
[TBL] [Abstract][Full Text] [Related]
14. Diethylnitrosamine enhances hepatic tumorigenic pathways in mice fed with high fat diet (Hfd).
Arboatti AS; Lambertucci F; Sedlmeier MG; Pisani G; Monti J; Álvarez ML; Francés DEA; Ronco MT; Carnovale CE
Chem Biol Interact; 2019 Apr; 303():70-78. PubMed ID: 30826251
[TBL] [Abstract][Full Text] [Related]
15. Skeletal muscle-specific knockout of DEP domain containing 5 protein increases mTORC1 signaling, muscle cell hypertrophy, and mitochondrial respiration.
Graber TG; Fry CS; Brightwell CR; Moro T; Maroto R; Bhattarai N; Porter C; Wakamiya M; Rasmussen BB
J Biol Chem; 2019 Mar; 294(11):4091-4102. PubMed ID: 30635399
[TBL] [Abstract][Full Text] [Related]
16. STARD1 promotes NASH-driven HCC by sustaining the generation of bile acids through the alternative mitochondrial pathway.
Conde de la Rosa L; Garcia-Ruiz C; Vallejo C; Baulies A; Nuñez S; Monte MJ; Marin JJG; Baila-Rueda L; Cenarro A; Civeira F; Fuster J; Garcia-Valdecasas JC; Ferrer J; Karin M; Ribas V; Fernandez-Checa JC
J Hepatol; 2021 Jun; 74(6):1429-1441. PubMed ID: 33515644
[TBL] [Abstract][Full Text] [Related]
17. STAT5 deficiency in hepatocytes reduces diethylnitrosamine-induced liver tumorigenesis in mice.
Kaltenecker D; Themanns M; Mueller KM; Spirk K; Golob-Schwarzl N; Friedbichler K; Kenner L; Haybaeck J; Moriggl R
Cytokine; 2019 Dec; 124():154573. PubMed ID: 30377054
[TBL] [Abstract][Full Text] [Related]
18. Immunopositivity for histone macroH2A1 isoforms marks steatosis-associated hepatocellular carcinoma.
Rappa F; Greco A; Podrini C; Cappello F; Foti M; Bourgoin L; Peyrou M; Marino A; Scibetta N; Williams R; Mazzoccoli G; Federici M; Pazienza V; Vinciguerra M
PLoS One; 2013; 8(1):e54458. PubMed ID: 23372727
[TBL] [Abstract][Full Text] [Related]
19. Liver-Specific Deletion of Mouse Tm6sf2 Promotes Steatosis, Fibrosis, and Hepatocellular Cancer.
Newberry EP; Hall Z; Xie Y; Molitor EA; Bayguinov PO; Strout GW; Fitzpatrick JAJ; Brunt EM; Griffin JL; Davidson NO
Hepatology; 2021 Sep; 74(3):1203-1219. PubMed ID: 33638902
[TBL] [Abstract][Full Text] [Related]
20. IL-17 signaling in steatotic hepatocytes and macrophages promotes hepatocellular carcinoma in alcohol-related liver disease.
Ma HY; Yamamoto G; Xu J; Liu X; Karin D; Kim JY; Alexandrov LB; Koyama Y; Nishio T; Benner C; Heinz S; Rosenthal SB; Liang S; Sun M; Karin G; Zhao P; Brodt P; Mckillop IH; Quehenberger O; Dennis E; Saltiel A; Tsukamoto H; Gao B; Karin M; Brenner DA; Kisseleva T
J Hepatol; 2020 May; 72(5):946-959. PubMed ID: 31899206
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]