BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

194 related articles for article (PubMed ID: 34563877)

  • 1. Design, synthesis, kinetic, molecular dynamics, and hypoglycemic effect characterization of new and potential selective benzimidazole derivatives as Protein Tyrosine Phosphatase 1B inhibitors.
    Campos-Almazán MI; Flores-Ramos M; Hernández-Campos A; Castillo R; Sierra-Campos E; Torgeson K; Peti W; Valdez-Solana M; Oria-Hernández J; Méndez ST; Castillo-Villanueva A; Jiménez-de Jesús H; Avitia-Domínguez C; Téllez-Valencia A
    Bioorg Med Chem; 2021 Oct; 48():116418. PubMed ID: 34563877
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Toward a treatment of diabesity: Rational design, synthesis and biological evaluation of benzene-sulfonamide derivatives as a new class of PTP-1B inhibitors.
    Ghareb N; El-Sayed NM; Abdelhameed R; Yamada K; Elgawish MS
    Bioorg Chem; 2019 May; 86():322-338. PubMed ID: 30743173
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Potential Inhibitors of Protein Tyrosine Phosphatase (PTP1B) Enzyme: Promising Target for Type-II Diabetes Mellitus.
    Nandi S; Saxena M
    Curr Top Med Chem; 2020; 20(29):2692-2707. PubMed ID: 32888269
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Design, synthesis and biological evaluation of some tetrazole acetamide derivatives as novel non-carboxylic PTP1B inhibitors.
    Maheshwari N; Karthikeyan C; Bhadada SV; Verma AK; Sahi C; Moorthy NSHN; Trivedi P
    Bioorg Chem; 2019 Nov; 92():103221. PubMed ID: 31499261
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Potent inhibition of protein tyrosine phosphatases by copper complexes with multi-benzimidazole derivatives.
    Li Y; Lu L; Zhu M; Wang Q; Yuan C; Xing S; Fu X; Mei Y
    Biometals; 2011 Dec; 24(6):993-1004. PubMed ID: 21618062
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Design and synthesis of tricyclic terpenoid derivatives as novel PTP1B inhibitors with improved pharmacological property and
    Yang L; Chen F; Gao C; Chen J; Li J; Liu S; Zhang Y; Wang Z; Qian S
    J Enzyme Inhib Med Chem; 2020 Dec; 35(1):152-164. PubMed ID: 31742469
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A Library of Thiazolidin-4-one Derivatives as Protein Tyrosine Phosphatase 1B (PTP1B) Inhibitors: An Attempt To Discover Novel Antidiabetic Agents.
    Patel AD; Pasha TY; Lunagariya P; Shah U; Bhambharoliya T; Tripathi RKP
    ChemMedChem; 2020 Jul; 15(13):1229-1242. PubMed ID: 32390300
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Design and evaluation of non-carboxylate 5-arylidene-2-thioxo-4-imidazolidinones as novel non-competitive inhibitors of protein tyrosine phosphatase 1B.
    Ottanà R; Paoli P; Lori G; Adornato I; Previti S; Naß A; Wolber G; Maccari R
    Bioorg Chem; 2019 Nov; 92():103211. PubMed ID: 31491569
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Novel Mixed-Type Inhibitors of Protein Tyrosine Phosphatase 1B. Kinetic and Computational Studies.
    Sarabia-Sánchez MJ; Trejo-Soto PJ; Velázquez-López JM; Carvente-García C; Castillo R; Hernández-Campos A; Avitia-Domínguez C; Enríquez-Mendiola D; Sierra-Campos E; Valdez-Solana M; Salas-Pacheco JM; Téllez-Valencia A
    Molecules; 2017 Dec; 22(12):. PubMed ID: 29261102
    [TBL] [Abstract][Full Text] [Related]  

  • 10. 2-Acyl-3-carboxyl-tetrahydroisoquinoline Derivatives: Mixed-Type PTP1B Inhibitors without PPARγ Activation.
    Morishita K; Shoji Y; Fukui M; Ito Y; Kitao T; Ozawa SI; Hirono S; Shirahase H
    Chem Pharm Bull (Tokyo); 2018; 66(12):1131-1152. PubMed ID: 30504630
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Design, synthesis and biological evaluation of uncharged catechol derivatives as selective inhibitors of PTP1B.
    Li XQ; Xu Q; Luo J; Wang LJ; Jiang B; Zhang RS; Shi DY
    Eur J Med Chem; 2017 Aug; 136():348-359. PubMed ID: 28511130
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Discovery of 5-(3-bromo-2-(2,3-dibromo-4,5-dimethoxybenzyl)-4,5-dimethoxybenzylidene)thiazolidine-2,4-dione as a novel potent protein tyrosine phosphatase 1B inhibitor with antidiabetic properties.
    Jiang B; Luo J; Guo S; Wang L
    Bioorg Chem; 2021 Mar; 108():104648. PubMed ID: 33493928
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Novel Non-carboxylate Benzoylsulfonamide-Based Protein Tyrosine Phosphatase 1B Inhibitors with Non-competitive Actions.
    Morishita K; Shoji Y; Tanaka S; Fukui M; Ito Y; Kitao T; Ozawa SI; Hirono S; Shirahase H
    Chem Pharm Bull (Tokyo); 2017; 65(12):1144-1160. PubMed ID: 29199219
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Hypoglycemic effect and mechanism of honokiol on type 2 diabetic mice.
    Sun J; Fu X; Liu Y; Wang Y; Huo B; Guo Y; Gao X; Li W; Hu X
    Drug Des Devel Ther; 2015; 9():6327-42. PubMed ID: 26674084
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Discovery of potent, selective and orally bioavailable triaryl-sulfonamide based PTP1B inhibitors.
    Patel D; Jain M; Shah SR; Bahekar R; Jadav P; Joharapurkar A; Dhanesha N; Shaikh M; Sairam KV; Kapadnis P
    Bioorg Med Chem Lett; 2012 Jan; 22(2):1111-7. PubMed ID: 22189136
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Identification and characterization of potent and selective inhibitors targeting protein tyrosine phosphatase 1B (PTP1B).
    Jin J; Ye X; Boateng D; Dai K; Ye F; Du P; Yu H
    Bioorg Med Chem Lett; 2019 Aug; 29(16):2358-2363. PubMed ID: 31221555
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Discovery of novel bromophenol 3,4-dibromo-5-(2-bromo-3,4-dihydroxy-6-(isobutoxymethyl)benzyl)benzene-1,2-diol as protein tyrosine phosphatase 1B inhibitor and its anti-diabetic properties in C57BL/KsJ-db/db mice.
    Jiang B; Guo S; Shi D; Guo C; Wang T
    Eur J Med Chem; 2013 Jun; 64():129-36. PubMed ID: 23644196
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis, SAR and docking studies of substituted aryl phenylthiazolyl phenylcarboxamide as potential protein tyrosine phosphatase 1B (PTP1B) inhibitors.
    Varshney K; Gupta AK; Rawat A; Srivastava R; Mishra A; Saxena M; Srivastava AK; Jain S; Saxena AK
    Chem Biol Drug Des; 2019 Jul; 94(1):1378-1389. PubMed ID: 30903642
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Discovery of novel high potent and cellular active ADC type PTP1B inhibitors with selectivity over TC-PTP via modification interacting with C site.
    Du Y; Zhang Y; Ling H; Li Q; Shen J
    Eur J Med Chem; 2018 Jan; 144():692-700. PubMed ID: 29289892
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Identification of protein tyrosine phosphatase 1B (PTP1B) inhibitors through De Novo Evoluton, synthesis, biological evaluation and molecular dynamics simulation.
    Wu J; Ma Y; Zhou H; Zhou L; Du S; Sun Y; Li W; Dong W; Wang R
    Biochem Biophys Res Commun; 2020 May; 526(1):273-280. PubMed ID: 32209254
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.