BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

158 related articles for article (PubMed ID: 34571002)

  • 1. EZH2 Inhibitor Enhances the STING Agonist‒Induced Antitumor Immunity in Melanoma.
    Xu T; Dai J; Tang L; Yang L; Si L; Sheng X; Cui C; Chi Z; Kong Y; Guo J
    J Invest Dermatol; 2022 Apr; 142(4):1158-1170.e8. PubMed ID: 34571002
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Dual Targeting with EZH2 Inhibitor and STING Agonist to Treat Melanoma.
    Emran AA; Fisher DE
    J Invest Dermatol; 2022 Apr; 142(4):1004-1006. PubMed ID: 35131084
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The Histone Methyltransferase Ezh2 Controls Mechanisms of Adaptive Resistance to Tumor Immunotherapy.
    Zingg D; Arenas-Ramirez N; Sahin D; Rosalia RA; Antunes AT; Haeusel J; Sommer L; Boyman O
    Cell Rep; 2017 Jul; 20(4):854-867. PubMed ID: 28746871
    [TBL] [Abstract][Full Text] [Related]  

  • 4. EZH2 as a mediator of treatment resistance in melanoma.
    Tiffen JC; Gallagher SJ; Tseng HY; Filipp FV; Fazekas de St. Groth B; Hersey P
    Pigment Cell Melanoma Res; 2016 Sep; 29(5):500-7. PubMed ID: 27063195
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Epigenetic reprogramming of tumor cell-intrinsic STING function sculpts antigenicity and T cell recognition of melanoma.
    Falahat R; Berglund A; Putney RM; Perez-Villarroel P; Aoyama S; Pilon-Thomas S; Barber GN; Mulé JJ
    Proc Natl Acad Sci U S A; 2021 Apr; 118(15):. PubMed ID: 33827917
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Epigenetic state determines the in vivo efficacy of STING agonist therapy.
    Falahat R; Berglund A; Perez-Villarroel P; Putney RM; Hamaidi I; Kim S; Pilon-Thomas S; Barber GN; Mulé JJ
    Nat Commun; 2023 Mar; 14(1):1573. PubMed ID: 36949064
    [TBL] [Abstract][Full Text] [Related]  

  • 7. EZH2 Cooperates with DNA Methylation to Downregulate Key Tumor Suppressors and IFN Gene Signatures in Melanoma.
    Tiffen J; Gallagher SJ; Filipp F; Gunatilake D; Emran AA; Cullinane C; Dutton-Register K; Aoude L; Hayward N; Chatterjee A; Rodger EJ; Eccles MR; Hersey P
    J Invest Dermatol; 2020 Dec; 140(12):2442-2454.e5. PubMed ID: 32360600
    [TBL] [Abstract][Full Text] [Related]  

  • 8. STING agonist loaded lipid nanoparticles overcome anti-PD-1 resistance in melanoma lung metastasis via NK cell activation.
    Nakamura T; Sato T; Endo R; Sasaki S; Takahashi N; Sato Y; Hyodo M; Hayakawa Y; Harashima H
    J Immunother Cancer; 2021 Jul; 9(7):. PubMed ID: 34215690
    [TBL] [Abstract][Full Text] [Related]  

  • 9. STING activation of tumor endothelial cells initiates spontaneous and therapeutic antitumor immunity.
    Demaria O; De Gassart A; Coso S; Gestermann N; Di Domizio J; Flatz L; Gaide O; Michielin O; Hwu P; Petrova TV; Martinon F; Modlin RL; Speiser DE; Gilliet M
    Proc Natl Acad Sci U S A; 2015 Dec; 112(50):15408-13. PubMed ID: 26607445
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Epigenetic reprogramming by tumor-derived EZH2 gain-of-function mutations promotes aggressive 3D cell morphologies and enhances melanoma tumor growth.
    Barsotti AM; Ryskin M; Zhong W; Zhang WG; Giannakou A; Loreth C; Diesl V; Follettie M; Golas J; Lee M; Nichols T; Fan C; Li G; Dann S; Fantin VR; Arndt K; Verhelle D; Rollins RA
    Oncotarget; 2015 Feb; 6(5):2928-38. PubMed ID: 25671303
    [TBL] [Abstract][Full Text] [Related]  

  • 11. EZH2, a prominent orchestrator of genetic and epigenetic regulation of solid tumor microenvironment and immunotherapy.
    Sun S; Yu F; Xu D; Zheng H; Li M
    Biochim Biophys Acta Rev Cancer; 2022 Mar; 1877(2):188700. PubMed ID: 35217116
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Antitumor effect of anti-vascular therapy with STING agonist depends on the tumor microenvironment context.
    Czapla J; Drzyzga A; Matuszczak S; Cichoń T; Rusin M; Jarosz-Biej M; Pilny E; Smolarczyk R
    Front Oncol; 2023; 13():1249524. PubMed ID: 37655095
    [TBL] [Abstract][Full Text] [Related]  

  • 13. STING Sensing of Murine Cytomegalovirus Alters the Tumor Microenvironment to Promote Antitumor Immunity.
    Wilski NA; Stotesbury C; Del Casale C; Montoya B; Wong E; Sigal LJ; Snyder CM
    J Immunol; 2020 Jun; 204(11):2961-2972. PubMed ID: 32284333
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Somatic Copy Number Amplification and Hyperactivating Somatic Mutations of EZH2 Correlate With DNA Methylation and Drive Epigenetic Silencing of Genes Involved in Tumor Suppression and Immune Responses in Melanoma.
    Tiffen J; Wilson S; Gallagher SJ; Hersey P; Filipp FV
    Neoplasia; 2016 Feb; 18(2):121-32. PubMed ID: 26936398
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The Development of STING Agonists and Emerging Results as a Cancer Immunotherapy.
    Hines JB; Kacew AJ; Sweis RF
    Curr Oncol Rep; 2023 Mar; 25(3):189-199. PubMed ID: 36705879
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mi-2β promotes immune evasion in melanoma by activating EZH2 methylation.
    Li C; Wang Z; Yao L; Lin X; Jian Y; Li Y; Zhang J; Shao J; Tran PD; Hagman JR; Cao M; Cong Y; Li HY; Goding CR; Xu ZX; Liao X; Miao X; Cui R
    Nat Commun; 2024 Mar; 15(1):2163. PubMed ID: 38461299
    [TBL] [Abstract][Full Text] [Related]  

  • 17. H3K27me3 and EZH2 expression in melanoma: relevance for melanoma progression and response to immune checkpoint blockade.
    Hoffmann F; Niebel D; Aymans P; Ferring-Schmitt S; Dietrich D; Landsberg J
    Clin Epigenetics; 2020 Feb; 12(1):24. PubMed ID: 32041674
    [TBL] [Abstract][Full Text] [Related]  

  • 18. EZH2 as a Regulator of CD8+ T Cell Fate and Function.
    Stairiker CJ; Thomas GD; Salek-Ardakani S
    Front Immunol; 2020; 11():593203. PubMed ID: 33117406
    [TBL] [Abstract][Full Text] [Related]  

  • 19. EZH2-CCF-cGAS Axis Promotes Breast Cancer Metastasis.
    Duan D; Shang M; Han Y; Liu J; Liu J; Kong SH; Hou J; Huang B; Lu J; Zhang Y
    Int J Mol Sci; 2022 Feb; 23(3):. PubMed ID: 35163710
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Zebularine elevates STING expression and enhances cGAMP cancer immunotherapy in mice.
    Lai J; Fu Y; Tian S; Huang S; Luo X; Lin L; Zhang X; Wang H; Lin Z; Zhao H; Lin S; Zhao J; Xu S; Li D; Cai S; Dong L; Qian J; Liang J; Li Q; Zhang Y; Fan J; Balderas R; Chen Q
    Mol Ther; 2021 May; 29(5):1758-1771. PubMed ID: 33571681
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.