BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

160 related articles for article (PubMed ID: 34571002)

  • 21. Zebularine elevates STING expression and enhances cGAMP cancer immunotherapy in mice.
    Lai J; Fu Y; Tian S; Huang S; Luo X; Lin L; Zhang X; Wang H; Lin Z; Zhao H; Lin S; Zhao J; Xu S; Li D; Cai S; Dong L; Qian J; Liang J; Li Q; Zhang Y; Fan J; Balderas R; Chen Q
    Mol Ther; 2021 May; 29(5):1758-1771. PubMed ID: 33571681
    [TBL] [Abstract][Full Text] [Related]  

  • 22. EZH2 inhibition activates a dsRNA-STING-interferon stress axis that potentiates response to PD-1 checkpoint blockade in prostate cancer.
    Morel KL; Sheahan AV; Burkhart DL; Baca SC; Boufaied N; Liu Y; Qiu X; Cañadas I; Roehle K; Heckler M; Calagua C; Ye H; Pantelidou C; Galbo P; Panja S; Mitrofanova A; Wilkinson S; Whitlock NC; Trostel SY; Hamid AA; Kibel AS; Barbie DA; Choudhury AD; Pomerantz MM; Sweeney CJ; Long HW; Einstein DJ; Shapiro GI; Dougan SK; Sowalsky AG; He HH; Freedman ML; Balk SP; Loda M; Labbé DP; Olson BM; Ellis L
    Nat Cancer; 2021 Apr; 2(4):444-456. PubMed ID: 33899001
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Cancer cell-intrinsic STING is associated with CD8 + T-cell infiltration and might serve as a potential immunotherapeutic target in hepatocellular carcinoma.
    Zhang Y; Zhai Q; Feng X; Chen D; Lu Y; Hu J; Xie H; Zhou L; Wu J; Zheng S
    Clin Transl Oncol; 2021 Jul; 23(7):1314-1324. PubMed ID: 33502741
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Enhancer of zeste homolog 2-catalysed H3K27 trimethylation plays a key role in acute-on-chronic liver failure via TNF-mediated pathway.
    Zhou T; Sun Y; Li M; Ding Y; Yin R; Li Z; Xie Q; Bao S; Cai W
    Cell Death Dis; 2018 May; 9(6):590. PubMed ID: 29789597
    [TBL] [Abstract][Full Text] [Related]  

  • 25. STING Promotes the Growth of Tumors Characterized by Low Antigenicity via IDO Activation.
    Lemos H; Mohamed E; Huang L; Ou R; Pacholczyk G; Arbab AS; Munn D; Mellor AL
    Cancer Res; 2016 Apr; 76(8):2076-81. PubMed ID: 26964621
    [TBL] [Abstract][Full Text] [Related]  

  • 26. EZH2-Mediated Downregulation of the Tumor Suppressor DAB2IP Maintains Ovarian Cancer Stem Cells.
    Zong X; Wang W; Ozes A; Fang F; Sandusky GE; Nephew KP
    Cancer Res; 2020 Oct; 80(20):4371-4385. PubMed ID: 32816909
    [TBL] [Abstract][Full Text] [Related]  

  • 27. STING Signaling in Melanoma Cells Shapes Antigenicity and Can Promote Antitumor T-cell Activity.
    Falahat R; Perez-Villarroel P; Mailloux AW; Zhu G; Pilon-Thomas S; Barber GN; Mulé JJ
    Cancer Immunol Res; 2019 Nov; 7(11):1837-1848. PubMed ID: 31462408
    [TBL] [Abstract][Full Text] [Related]  

  • 28. AGE-Induced Suppression of EZH2 Mediates Injury of Podocytes by Reducing H3K27me3.
    Liebisch M; Wolf G
    Am J Nephrol; 2020; 51(9):676-692. PubMed ID: 32854097
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Celecoxib promotes the efficacy of STING-targeted therapy by increasing antitumor CD8
    Kosaka A; Yajima Y; Yasuda S; Komatsuda H; Nagato T; Oikawa K; Kobayashi H; Ohkuri T
    Int J Cancer; 2023 Apr; 152(8):1685-1697. PubMed ID: 36495276
    [TBL] [Abstract][Full Text] [Related]  

  • 30. PRMT5 functionally associates with EZH2 to promote colorectal cancer progression through epigenetically repressing CDKN2B expression.
    Yang L; Ma DW; Cao YP; Li DZ; Zhou X; Feng JF; Bao J
    Theranostics; 2021; 11(8):3742-3759. PubMed ID: 33664859
    [No Abstract]   [Full Text] [Related]  

  • 31. Epigenetic silencing of microRNA-218 via EZH2-mediated H3K27 trimethylation is involved in malignant transformation of HBE cells induced by cigarette smoke extract.
    Wang B; Liu Y; Luo F; Xu Y; Qin Y; Lu X; Xu W; Shi L; Liu Q; Xiang Q
    Arch Toxicol; 2016 Feb; 90(2):449-61. PubMed ID: 25526925
    [TBL] [Abstract][Full Text] [Related]  

  • 32. The Ezh2 polycomb group protein drives an aggressive phenotype in melanoma cancer stem cells and is a target of diet derived sulforaphane.
    Fisher ML; Adhikary G; Grun D; Kaetzel DM; Eckert RL
    Mol Carcinog; 2016 Dec; 55(12):2024-2036. PubMed ID: 26693692
    [TBL] [Abstract][Full Text] [Related]  

  • 33. STING Activated Tumor-Intrinsic Type I Interferon Signaling Promotes CXCR3 Dependent Antitumor Immunity in Pancreatic Cancer.
    Vonderhaar EP; Barnekow NS; McAllister D; McOlash L; Eid MA; Riese MJ; Tarakanova VL; Johnson BD; Dwinell MB
    Cell Mol Gastroenterol Hepatol; 2021; 12(1):41-58. PubMed ID: 33548597
    [TBL] [Abstract][Full Text] [Related]  

  • 34. LncRNA MEG3 inhibits the progression of prostate cancer by facilitating H3K27 trimethylation of EN2 through binding to EZH2.
    Zhou Y; Yang H; Xia W; Cui L; Xu R; Lu H; Xue D; Tian Z; Ding T; Cao Y; Shi Q; He X
    J Biochem; 2020 Mar; 167(3):295-301. PubMed ID: 31790140
    [TBL] [Abstract][Full Text] [Related]  

  • 35. PRMT5 control of cGAS/STING and NLRC5 pathways defines melanoma response to antitumor immunity.
    Kim H; Kim H; Feng Y; Li Y; Tamiya H; Tocci S; Ronai ZA
    Sci Transl Med; 2020 Jul; 12(551):. PubMed ID: 32641491
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Identification of coexistence of BRAF V600E mutation and EZH2 gain specifically in melanoma as a promising target for combination therapy.
    Yu H; Ma M; Yan J; Xu L; Yu J; Dai J; Xu T; Tang H; Wu X; Li S; Lian B; Mao L; Chi Z; Cui C; Guo J; Kong Y
    J Transl Med; 2017 Dec; 15(1):243. PubMed ID: 29202777
    [TBL] [Abstract][Full Text] [Related]  

  • 37. A nanoparticle-incorporated STING activator enhances antitumor immunity in PD-L1-insensitive models of triple-negative breast cancer.
    Cheng N; Watkins-Schulz R; Junkins RD; David CN; Johnson BM; Montgomery SA; Peine KJ; Darr DB; Yuan H; McKinnon KP; Liu Q; Miao L; Huang L; Bachelder EM; Ainslie KM; Ting JP
    JCI Insight; 2018 Nov; 3(22):. PubMed ID: 30429378
    [TBL] [Abstract][Full Text] [Related]  

  • 38. EZH2 Inhibition Interferes With the Activation of Type I Interferon Signaling Pathway and Ameliorates Lupus Nephritis in NZB/NZW F1 Mice.
    Wu L; Jiang X; Qi C; Zhang C; Qu B; Shen N
    Front Immunol; 2021; 12():653989. PubMed ID: 33868295
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Targeting Epigenetic Crosstalk as a Therapeutic Strategy for EZH2-Aberrant Solid Tumors.
    Huang X; Yan J; Zhang M; Wang Y; Chen Y; Fu X; Wei R; Zheng XL; Liu Z; Zhang X; Yang H; Hao B; Shen YY; Su Y; Cong X; Huang M; Tan M; Ding J; Geng M
    Cell; 2018 Sep; 175(1):186-199.e19. PubMed ID: 30220457
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Multifaceted role of the polycomb-group gene EZH2 in hematological malignancies.
    Sashida G; Iwama A
    Int J Hematol; 2017 Jan; 105(1):23-30. PubMed ID: 27830540
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 8.