BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

233 related articles for article (PubMed ID: 34571904)

  • 1. Cell-Permeable Succinate Increases Mitochondrial Membrane Potential and Glycolysis in Leigh Syndrome Patient Fibroblasts.
    Bakare AB; Rao RR; Iyer S
    Cells; 2021 Aug; 10(9):. PubMed ID: 34571904
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Rescue from galactose-induced death of Leigh Syndrome patient cells by pyruvate and NAD
    Iannetti EF; Smeitink JAM; Willems PHGM; Beyrath J; Koopman WJH
    Cell Death Dis; 2018 Nov; 9(11):1135. PubMed ID: 30429455
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Evaluating the Bioenergetics Health Index Ratio in Leigh Syndrome Fibroblasts to Understand Disease Severity.
    Bakare AB; Dean J; Chen Q; Thorat V; Huang Y; LaFramboise T; Lesnefsky EJ; Iyer S
    Int J Mol Sci; 2021 Sep; 22(19):. PubMed ID: 34638685
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Quantifying small molecule phenotypic effects using mitochondrial morpho-functional fingerprinting and machine learning.
    Blanchet L; Smeitink JA; van Emst-de Vries SE; Vogels C; Pellegrini M; Jonckheere AI; Rodenburg RJ; Buydens LM; Beyrath J; Willems PH; Koopman WJ
    Sci Rep; 2015 Jan; 5():8035. PubMed ID: 25620325
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Cell-permeable succinate prodrugs bypass mitochondrial complex I deficiency.
    Ehinger JK; Piel S; Ford R; Karlsson M; Sjövall F; Frostner EÅ; Morota S; Taylor RW; Turnbull DM; Cornell C; Moss SJ; Metzsch C; Hansson MJ; Fliri H; Elmér E
    Nat Commun; 2016 Aug; 7():12317. PubMed ID: 27502960
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Effect of thyroid hormone on mitochondrial properties and oxidative stress in cells from patients with mtDNA defects.
    Menzies KJ; Robinson BH; Hood DA
    Am J Physiol Cell Physiol; 2009 Feb; 296(2):C355-62. PubMed ID: 19036942
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The pleiotropic effects of decanoic acid treatment on mitochondrial function in fibroblasts from patients with complex I deficient Leigh syndrome.
    Kanabus M; Fassone E; Hughes SD; Bilooei SF; Rutherford T; Donnell MO; Heales SJR; Rahman S
    J Inherit Metab Dis; 2016 May; 39(3):415-426. PubMed ID: 27080638
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Impaired Cellular Bioenergetics Causes Mitochondrial Calcium Handling Defects in MT-ND5 Mutant Cybrids.
    McKenzie M; Duchen MR
    PLoS One; 2016; 11(4):e0154371. PubMed ID: 27110715
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Metabolic rescue in pluripotent cells from patients with mtDNA disease.
    Ma H; Folmes CD; Wu J; Morey R; Mora-Castilla S; Ocampo A; Ma L; Poulton J; Wang X; Ahmed R; Kang E; Lee Y; Hayama T; Li Y; Van Dyken C; Gutierrez NM; Tippner-Hedges R; Koski A; Mitalipov N; Amato P; Wolf DP; Huang T; Terzic A; Laurent LC; Izpisua Belmonte JC; Mitalipov S
    Nature; 2015 Aug; 524(7564):234-8. PubMed ID: 26176921
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Region-Specific Defects of Respiratory Capacities in the Ndufs4(KO) Mouse Brain.
    Kayser EB; Sedensky MM; Morgan PG
    PLoS One; 2016; 11(1):e0148219. PubMed ID: 26824698
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The effect of small molecules on nuclear-encoded translation diseases.
    Soiferman D; Ayalon O; Weissman S; Saada A
    Biochimie; 2014 May; 100():184-91. PubMed ID: 24012549
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mitochondrial vulnerability and increased susceptibility to nutrient-induced cytotoxicity in fibroblasts from leigh syndrome French canadian patients.
    Burelle Y; Bemeur C; Rivard ME; Thompson Legault J; Boucher G; ; Morin C; Coderre L; Des Rosiers C
    PLoS One; 2015; 10(3):e0120767. PubMed ID: 25835550
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Apomorphine rescues reactive oxygen species-induced apoptosis of fibroblasts with mitochondrial disease.
    Miyauchi A; Kouga T; Jimbo EF; Matsuhashi T; Abe T; Yamagata T; Osaka H
    Mitochondrion; 2019 Nov; 49():111-120. PubMed ID: 31356884
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mutations in the ND5 subunit of complex I of the mitochondrial DNA are a frequent cause of oxidative phosphorylation disease.
    Blok MJ; Spruijt L; de Coo IF; Schoonderwoerd K; Hendrickx A; Smeets HJ
    J Med Genet; 2007 Apr; 44(4):e74. PubMed ID: 17400793
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Modulation of mitochondrial dysfunction-related oxidative stress in fibroblasts of patients with Leigh syndrome by inhibition of prooxidative p66Shc pathway.
    Wojtala A; Karkucinska-Wieckowska A; Sardao VA; Szczepanowska J; Kowalski P; Pronicki M; Duszynski J; Wieckowski MR
    Mitochondrion; 2017 Nov; 37():62-79. PubMed ID: 28739512
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mitochondrial respiratory chain complex I dysfunction induced by N-methyl carbamate ex vivo can be alleviated with a cell-permeable succinate prodrug.
    Janowska JI; Piel S; Saliba N; Kim CD; Jang DH; Karlsson M; Kilbaugh TJ; Ehinger JK
    Toxicol In Vitro; 2020 Jun; 65():104794. PubMed ID: 32057835
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The G13513A mutation in the ND5 gene of mitochondrial DNA as a common cause of MELAS or Leigh syndrome: evidence from 12 cases.
    Shanske S; Coku J; Lu J; Ganesh J; Krishna S; Tanji K; Bonilla E; Naini AB; Hirano M; DiMauro S
    Arch Neurol; 2008 Mar; 65(3):368-72. PubMed ID: 18332249
    [TBL] [Abstract][Full Text] [Related]  

  • 18. NDUFS4 deletion triggers loss of NDUFA12 in Ndufs4
    Adjobo-Hermans MJW; de Haas R; Willems PHGM; Wojtala A; van Emst-de Vries SE; Wagenaars JA; van den Brand M; Rodenburg RJ; Smeitink JAM; Nijtmans LG; Sazanov LA; Wieckowski MR; Koopman WJH
    Biochim Biophys Acta Bioenerg; 2020 Aug; 1861(8):148213. PubMed ID: 32335026
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Allotopic mRNA localization to the mitochondrial surface rescues respiratory chain defects in fibroblasts harboring mitochondrial DNA mutations affecting complex I or v subunits.
    Bonnet C; Kaltimbacher V; Ellouze S; Augustin S; Bénit P; Forster V; Rustin P; Sahel JA; Corral-Debrinski M
    Rejuvenation Res; 2007 Jun; 10(2):127-44. PubMed ID: 17518546
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Evaluation of mitochondrial bioenergetics, dynamics, endoplasmic reticulum-mitochondria crosstalk, and reactive oxygen species in fibroblasts from patients with complex I deficiency.
    Leipnitz G; Mohsen AW; Karunanidhi A; Seminotti B; Roginskaya VY; Markantone DM; Grings M; Mihalik SJ; Wipf P; Van Houten B; Vockley J
    Sci Rep; 2018 Jan; 8(1):1165. PubMed ID: 29348607
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.