190 related articles for article (PubMed ID: 34580712)
21. Identification of Wee1 as a novel therapeutic target for mutant RAS-driven acute leukemia and other malignancies.
Weisberg E; Nonami A; Chen Z; Liu F; Zhang J; Sattler M; Nelson E; Cowens K; Christie AL; Mitsiades C; Wong KK; Liu Q; Gray N; Griffin JD
Leukemia; 2015 Jan; 29(1):27-37. PubMed ID: 24791855
[TBL] [Abstract][Full Text] [Related]
22. Oncogenic NRAS Primes Primary Acute Myeloid Leukemia Cells for Differentiation.
Brendel C; Teichler S; Millahn A; Stiewe T; Krause M; Stabla K; Ross P; Huynh M; Illmer T; Mernberger M; Barckhausen C; Neubauer A
PLoS One; 2015; 10(4):e0123181. PubMed ID: 25901794
[TBL] [Abstract][Full Text] [Related]
23. Upregulation of IGF1R by mutant RAS in leukemia and potentiation of RAS signaling inhibitors by small-molecule inhibition of IGF1R.
Weisberg E; Nonami A; Chen Z; Nelson E; Chen Y; Liu F; Cho H; Zhang J; Sattler M; Mitsiades C; Wong KK; Liu Q; Gray NS; Griffin JD
Clin Cancer Res; 2014 Nov; 20(21):5483-95. PubMed ID: 25186968
[TBL] [Abstract][Full Text] [Related]
24. Echinomycin, a potential binder of FKBP12, shows minor effect on calcineurin activity.
Singh V; Nand A; Chen C; Li Z; Li SJ; Wang S; Yang M; Merino A; Zhang L; Zhu J
J Biomol Screen; 2014 Oct; 19(9):1275-81. PubMed ID: 25085862
[TBL] [Abstract][Full Text] [Related]
25. Features of Ras activation by a mislocalized oncogenic tyrosine kinase: FLT3 ITD signals through K-Ras at the plasma membrane of acute myeloid leukemia cells.
Köthe S; Müller JP; Böhmer SA; Tschongov T; Fricke M; Koch S; Thiede C; Requardt RP; Rubio I; Böhmer FD
J Cell Sci; 2013 Oct; 126(Pt 20):4746-55. PubMed ID: 23943874
[TBL] [Abstract][Full Text] [Related]
26. Inhibiting oncogenic signaling by sorafenib activates PUMA via GSK3β and NF-κB to suppress tumor cell growth.
Dudgeon C; Peng R; Wang P; Sebastiani A; Yu J; Zhang L
Oncogene; 2012 Nov; 31(46):4848-58. PubMed ID: 22286758
[TBL] [Abstract][Full Text] [Related]
27. Loss of wild-type Kras promotes activation of all Ras isoforms in oncogenic Kras-induced leukemogenesis.
Kong G; Chang YI; Damnernsawad A; You X; Du J; Ranheim EA; Lee W; Ryu MJ; Zhou Y; Xing Y; Chang Q; Burd CE; Zhang J
Leukemia; 2016 Jul; 30(7):1542-51. PubMed ID: 27055865
[TBL] [Abstract][Full Text] [Related]
28. Hematopoiesis and leukemogenesis in mice expressing oncogenic NrasG12D from the endogenous locus.
Li Q; Haigis KM; McDaniel A; Harding-Theobald E; Kogan SC; Akagi K; Wong JC; Braun BS; Wolff L; Jacks T; Shannon K
Blood; 2011 Feb; 117(6):2022-32. PubMed ID: 21163920
[TBL] [Abstract][Full Text] [Related]
29. H-, K- and N-Ras inhibit myeloid leukemia cell proliferation by a p21WAF1-dependent mechanism.
Delgado MD; Vaqué JP; Arozarena I; López-Ilasaca MA; Martínez C; Crespo P; León J
Oncogene; 2000 Feb; 19(6):783-90. PubMed ID: 10698496
[TBL] [Abstract][Full Text] [Related]
30. N-ras oncogene-induced gene expression in human hematopoietic progenitor cells: upregulation of p16INK4a and p21CIP1/WAF1 correlates with myeloid differentiation.
Shen S; Passioura T; Symonds G; Dolnikov A
Exp Hematol; 2007 Jun; 35(6):908-19. PubMed ID: 17533045
[TBL] [Abstract][Full Text] [Related]
31. Mouse model for NRAS-induced leukemogenesis.
Parikh C; Ren R
Methods Enzymol; 2008; 439():15-24. PubMed ID: 18374153
[TBL] [Abstract][Full Text] [Related]
32. Pin1 inhibition exerts potent activity against acute myeloid leukemia through blocking multiple cancer-driving pathways.
Lian X; Lin YM; Kozono S; Herbert MK; Li X; Yuan X; Guo J; Guo Y; Tang M; Lin J; Huang Y; Wang B; Qiu C; Tsai CY; Xie J; Gao ZJ; Wu Y; Liu H; Zhou XZ; Lu KP; Chen Y
J Hematol Oncol; 2018 May; 11(1):73. PubMed ID: 29848341
[TBL] [Abstract][Full Text] [Related]
33. [Mutations of growth factor receptor Flt3 in acute myeloid leukemia: transformation of myeloid cells by Ras-dependent and Ras-independent mechanisms].
Müller-Tidow C; Steur C; Mizuki M; Schwäble J; Brandts C; Berdel WE; Serve H
Dtsch Med Wochenschr; 2002 Oct; 127(42):2195-200. PubMed ID: 12397548
[TBL] [Abstract][Full Text] [Related]
34. Hematopoietic transforming potential of activated ras in chimeric mice.
Hawley RG; Fong AZ; Ngan BY; Hawley TS
Oncogene; 1995 Sep; 11(6):1113-23. PubMed ID: 7566971
[TBL] [Abstract][Full Text] [Related]
35. Oncogenic Kras-induced leukemogeneis: hematopoietic stem cells as the initial target and lineage-specific progenitors as the potential targets for final leukemic transformation.
Zhang J; Wang J; Liu Y; Sidik H; Young KH; Lodish HF; Fleming MD
Blood; 2009 Feb; 113(6):1304-14. PubMed ID: 19066392
[TBL] [Abstract][Full Text] [Related]
36. Frequent loss of RAF kinase inhibitor protein expression in acute myeloid leukemia.
Zebisch A; Wölfler A; Fried I; Wolf O; Lind K; Bodner C; Haller M; Drasche A; Pirkebner D; Matallanas D; Rath O; Blyth K; Delwel R; Taskesen E; Quehenberger F; Kolch W; Troppmair J; Sill H
Leukemia; 2012 Aug; 26(8):1842-9. PubMed ID: 22388727
[TBL] [Abstract][Full Text] [Related]
37. Dual phosphoinositide 3-kinase/mammalian target of rapamycin blockade is an effective radiosensitizing strategy for the treatment of non-small cell lung cancer harboring K-RAS mutations.
Konstantinidou G; Bey EA; Rabellino A; Schuster K; Maira MS; Gazdar AF; Amici A; Boothman DA; Scaglioni PP
Cancer Res; 2009 Oct; 69(19):7644-52. PubMed ID: 19789349
[TBL] [Abstract][Full Text] [Related]
38. A dominant role for the c-Jun NH2-terminal kinase in oncogenic ras-induced morphologic transformation of human lung carcinoma cells.
Xiao L; Lang W
Cancer Res; 2000 Jan; 60(2):400-8. PubMed ID: 10667594
[TBL] [Abstract][Full Text] [Related]
39. Echinomycin in the prevention of heterotopic ossification - an experimental antibiotic agent shows promising results in a murine model.
Zimmermann SM; Würgler-Hauri CC; Wanner GA; Simmen HP; Werner CM
Injury; 2013 Apr; 44(4):570-5. PubMed ID: 23398900
[TBL] [Abstract][Full Text] [Related]
40. Dual effect of echinomycin on hypoxia-inducible factor-1 activity under normoxic and hypoxic conditions.
Vlaminck B; Toffoli S; Ghislain B; Demazy C; Raes M; Michiels C
FEBS J; 2007 Nov; 274(21):5533-42. PubMed ID: 17916190
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
