182 related articles for article (PubMed ID: 34588186)
1. Imeglimin Ameliorates β-Cell Apoptosis by Modulating the Endoplasmic Reticulum Homeostasis Pathway.
Li J; Inoue R; Togashi Y; Okuyama T; Satoh A; Kyohara M; Nishiyama K; Tsuno T; Miyashita D; Kin T; Shapiro AMJ; Chew RSE; Teo AKK; Oyadomari S; Terauchi Y; Shirakawa J
Diabetes; 2022 Mar; 71(3):424-439. PubMed ID: 34588186
[TBL] [Abstract][Full Text] [Related]
2. The proapoptotic BH3-only proteins Bim and Puma are downstream of endoplasmic reticulum and mitochondrial oxidative stress in pancreatic islets in response to glucotoxicity.
Wali JA; Rondas D; McKenzie MD; Zhao Y; Elkerbout L; Fynch S; Gurzov EN; Akira S; Mathieu C; Kay TW; Overbergh L; Strasser A; Thomas HE
Cell Death Dis; 2014 Mar; 5(3):e1124. PubMed ID: 24625983
[TBL] [Abstract][Full Text] [Related]
3. Endoplasmic reticulum stress contributes to NMDA-induced pancreatic β-cell dysfunction in a CHOP-dependent manner.
Huang XT; Liu W; Zhou Y; Sun M; Sun CC; Zhang CY; Tang SY
Life Sci; 2019 Sep; 232():116612. PubMed ID: 31260687
[TBL] [Abstract][Full Text] [Related]
4. Imeglimin preserves islet β-cell mass in Type 2 diabetic ZDF rats.
Hallakou-Bozec S; Kergoat M; Moller DE; Bolze S
Endocrinol Diabetes Metab; 2021 Apr; 4(2):e00193. PubMed ID: 33855202
[TBL] [Abstract][Full Text] [Related]
5. Identification of 1,2,3-triazole derivatives that protect pancreatic β cells against endoplasmic reticulum stress-mediated dysfunction and death through the inhibition of C/EBP-homologous protein expression.
Duan H; Arora D; Li Y; Setiadi H; Xu D; Lim HY; Wang W
Bioorg Med Chem; 2016 Jun; 24(12):2621-30. PubMed ID: 27157393
[TBL] [Abstract][Full Text] [Related]
6. The Orphan Nuclear Receptor NR4A1 Protects Pancreatic β-Cells from Endoplasmic Reticulum (ER) Stress-mediated Apoptosis.
Yu C; Cui S; Zong C; Gao W; Xu T; Gao P; Chen J; Qin D; Guan Q; Liu Y; Fu Y; Li X; Wang X
J Biol Chem; 2015 Aug; 290(34):20687-20699. PubMed ID: 26157144
[TBL] [Abstract][Full Text] [Related]
7. The endoplasmic reticulum in pancreatic beta cells of type 2 diabetes patients.
Marchetti P; Bugliani M; Lupi R; Marselli L; Masini M; Boggi U; Filipponi F; Weir GC; Eizirik DL; Cnop M
Diabetologia; 2007 Dec; 50(12):2486-94. PubMed ID: 17906960
[TBL] [Abstract][Full Text] [Related]
8. Glucokinase activation ameliorates ER stress-induced apoptosis in pancreatic β-cells.
Shirakawa J; Togashi Y; Sakamoto E; Kaji M; Tajima K; Orime K; Inoue H; Kubota N; Kadowaki T; Terauchi Y
Diabetes; 2013 Oct; 62(10):3448-58. PubMed ID: 23801577
[TBL] [Abstract][Full Text] [Related]
9. Di(2-ethylhexyl) phthalate-induced apoptosis in rat INS-1 cells is dependent on activation of endoplasmic reticulum stress and suppression of antioxidant protection.
Sun X; Lin Y; Huang Q; Shi J; Qiu L; Kang M; Chen Y; Fang C; Ye T; Dong S
J Cell Mol Med; 2015 Mar; 19(3):581-94. PubMed ID: 25418486
[TBL] [Abstract][Full Text] [Related]
10. Imeglimin mitigates the accumulation of dysfunctional mitochondria to restore insulin secretion and suppress apoptosis of pancreatic β-cells from db/db mice.
Aoyagi K; Nishiwaki C; Nakamichi Y; Yamashita SI; Kanki T; Ohara-Imaizumi M
Sci Rep; 2024 Mar; 14(1):6178. PubMed ID: 38485716
[TBL] [Abstract][Full Text] [Related]
11. A novel mechanism of imeglimin-mediated insulin secretion via the cADPR-TRP channel pathway.
Funazaki S; Yoshida M; Yamada H; Kakei M; Kawakami M; Nagashima S; Hara K; Dezaki K
J Diabetes Investig; 2022 Jan; 13(1):34-41. PubMed ID: 34523242
[TBL] [Abstract][Full Text] [Related]
12. Inhibition of GADD34, the stress-inducible regulatory subunit of the endoplasmic reticulum stress response, does not enhance functional recovery after spinal cord injury.
Ohri SS; Mullins A; Hetman M; Whittemore SR
PLoS One; 2014; 9(11):e109703. PubMed ID: 25386686
[TBL] [Abstract][Full Text] [Related]
13. PPARγ-inactive Δ2-troglitazone independently triggers ER stress and apoptosis in breast cancer cells.
Colin-Cassin C; Yao X; Cerella C; Chbicheb S; Kuntz S; Mazerbourg S; Boisbrun M; Chapleur Y; Diederich M; Flament S; Grillier-Vuissoz I
Mol Carcinog; 2015 May; 54(5):393-404. PubMed ID: 24293218
[TBL] [Abstract][Full Text] [Related]
14. Dienogest regulates apoptosis, proliferation, and invasiveness of endometriotic cyst stromal cells via endoplasmic reticulum stress induction.
Choi J; Jo M; Lee E; Lee DY; Choi D
Mol Hum Reprod; 2020 Jan; 26(1):30-39. PubMed ID: 31814016
[TBL] [Abstract][Full Text] [Related]
15. Phosphorylation of eIF2α attenuates statin-induced apoptosis by inhibiting the stabilization and translocation of p53 to the mitochondria.
Lee SK; Kim YS
Int J Oncol; 2013 Mar; 42(3):810-6. PubMed ID: 23354132
[TBL] [Abstract][Full Text] [Related]
16. Inhibition of palmitate-induced GADD34 expression augments apoptosis in mouse insulinoma cells (MIN6).
Fransson L; Sjöholm A; Ortsäter H
Cell Biochem Funct; 2014 Jul; 32(5):445-52. PubMed ID: 24633916
[TBL] [Abstract][Full Text] [Related]
17. Hypoxia reduces ER-to-Golgi protein trafficking and increases cell death by inhibiting the adaptive unfolded protein response in mouse beta cells.
Bensellam M; Maxwell EL; Chan JY; Luzuriaga J; West PK; Jonas JC; Gunton JE; Laybutt DR
Diabetologia; 2016 Jul; 59(7):1492-1502. PubMed ID: 27039902
[TBL] [Abstract][Full Text] [Related]
18. Oleic acid protects insulin-secreting INS-1E cells against palmitic acid-induced lipotoxicity along with an amelioration of ER stress.
Liu X; Zeng X; Chen X; Luo R; Li L; Wang C; Liu J; Cheng J; Lu Y; Chen Y
Endocrine; 2019 Jun; 64(3):512-524. PubMed ID: 30778898
[TBL] [Abstract][Full Text] [Related]
19. Chop deletion reduces oxidative stress, improves beta cell function, and promotes cell survival in multiple mouse models of diabetes.
Song B; Scheuner D; Ron D; Pennathur S; Kaufman RJ
J Clin Invest; 2008 Oct; 118(10):3378-89. PubMed ID: 18776938
[TBL] [Abstract][Full Text] [Related]
20. Imeglimin exerts favorable effects on pancreatic β-cells by improving morphology in mitochondria and increasing the number of insulin granules.
Sanada J; Obata A; Fushimi Y; Kimura T; Shimoda M; Ikeda T; Nogami Y; Obata Y; Yamasaki Y; Nakanishi S; Mune T; Kaku K; Kaneto H
Sci Rep; 2022 Aug; 12(1):13220. PubMed ID: 35918386
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
