BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

209 related articles for article (PubMed ID: 34589086)

  • 1. UNC93B1 Is Widely Expressed in the Murine CNS and Is Required for Neuroinflammation and Neuronal Injury Induced by MicroRNA
    Klammer MG; Dzaye O; Wallach T; Krüger C; Gaessler D; Buonfiglioli A; Derkow K; Kettenmann H; Brinkmann MM; Lehnardt S
    Front Immunol; 2021; 12():715774. PubMed ID: 34589086
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The Chaperone UNC93B1 Regulates Toll-like Receptor Stability Independently of Endosomal TLR Transport.
    Pelka K; Bertheloot D; Reimer E; Phulphagar K; Schmidt SV; Christ A; Stahl R; Watson N; Miyake K; Hacohen N; Haas A; Brinkmann MM; Marshak-Rothstein A; Meissner F; Latz E
    Immunity; 2018 May; 48(5):911-922.e7. PubMed ID: 29768176
    [TBL] [Abstract][Full Text] [Related]  

  • 3. UNC93B1 and nucleic acid-sensing Toll-like receptors mediate host resistance to infection with Leishmania major.
    Schamber-Reis BL; Petritus PM; Caetano BC; Martinez ER; Okuda K; Golenbock D; Scott P; Gazzinelli RT
    J Biol Chem; 2013 Mar; 288(10):7127-36. PubMed ID: 23325805
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Microglial-derived miRNA let-7 and HMGB1 contribute to ethanol-induced neurotoxicity via TLR7.
    Coleman LG; Zou J; Crews FT
    J Neuroinflammation; 2017 Jan; 14(1):22. PubMed ID: 28118842
    [TBL] [Abstract][Full Text] [Related]  

  • 5. An unconventional role for miRNA: let-7 activates Toll-like receptor 7 and causes neurodegeneration.
    Lehmann SM; Krüger C; Park B; Derkow K; Rosenberger K; Baumgart J; Trimbuch T; Eom G; Hinz M; Kaul D; Habbel P; Kälin R; Franzoni E; Rybak A; Nguyen D; Veh R; Ninnemann O; Peters O; Nitsch R; Heppner FL; Golenbock D; Schott E; Ploegh HL; Wulczyn FG; Lehnardt S
    Nat Neurosci; 2012 Jun; 15(6):827-35. PubMed ID: 22610069
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Necrotic neurons enhance microglial neurotoxicity through induction of glutaminase by a MyD88-dependent pathway.
    Pais TF; Figueiredo C; Peixoto R; Braz MH; Chatterjee S
    J Neuroinflammation; 2008 Oct; 5():43. PubMed ID: 18844999
    [TBL] [Abstract][Full Text] [Related]  

  • 7. MicroRNA-100-5p and microRNA-298-5p released from apoptotic cortical neurons are endogenous Toll-like receptor 7/8 ligands that contribute to neurodegeneration.
    Wallach T; Mossmann ZJ; Szczepek M; Wetzel M; Machado R; Raden M; Miladi M; Kleinau G; Krüger C; Dembny P; Adler D; Zhai Y; Kumbol V; Dzaye O; Schüler J; Futschik M; Backofen R; Scheerer P; Lehnardt S
    Mol Neurodegener; 2021 Nov; 16(1):80. PubMed ID: 34838071
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The impact of single and pairwise Toll-like receptor activation on neuroinflammation and neurodegeneration.
    Rosenberger K; Derkow K; Dembny P; Krüger C; Schott E; Lehnardt S
    J Neuroinflammation; 2014 Sep; 11():166. PubMed ID: 25239168
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Japanese Encephalitis Virus-induced let-7a/b interacted with the NOTCH-TLR7 pathway in microglia and facilitated neuronal death via caspase activation.
    Mukherjee S; Akbar I; Kumari B; Vrati S; Basu A; Banerjee A
    J Neurochem; 2019 May; 149(4):518-534. PubMed ID: 30556910
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Location is everything: let-7b microRNA and TLR7 signaling results in a painful TRP.
    Winkler CW; Taylor KG; Peterson KE
    Sci Signal; 2014 May; 7(327):pe14. PubMed ID: 24866018
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Large-scale mutational analysis identifies UNC93B1 variants that drive TLR-mediated autoimmunity in mice and humans.
    Rael VE; Yano JA; Huizar JP; Slayden LC; Weiss MA; Turcotte EA; Terry JM; Zuo W; Thiffault I; Pastinen T; Farrow EG; Jenkins JL; Becker ML; Wong SC; Stevens AM; Otten C; Allenspach EJ; Bonner DE; Bernstein JA; Wheeler MT; Saxton RA; ; Liu B; Majer O; Barton GM
    J Exp Med; 2024 Aug; 221(8):. PubMed ID: 38780621
    [TBL] [Abstract][Full Text] [Related]  

  • 12. An ENU-induced splicing mutation reveals a role for Unc93b1 in early immune cell activation following influenza A H1N1 infection.
    Lafferty EI; Flaczyk A; Angers I; Homer R; d'Hennezel E; Malo D; Piccirillo CA; Vidal SM; Qureshi ST
    Genes Immun; 2014; 15(5):320-32. PubMed ID: 24848930
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Identification of CNS Injury-Related microRNAs as Novel Toll-Like Receptor 7/8 Signaling Activators by Small RNA Sequencing.
    Wallach T; Wetzel M; Dembny P; Staszewski O; Krüger C; Buonfiglioli A; Prinz M; Lehnardt S
    Cells; 2020 Jan; 9(1):. PubMed ID: 31940779
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Cryo-EM structures of Toll-like receptors in complex with UNC93B1.
    Ishida H; Asami J; Zhang Z; Nishizawa T; Shigematsu H; Ohto U; Shimizu T
    Nat Struct Mol Biol; 2021 Feb; 28(2):173-180. PubMed ID: 33432245
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Intrathecal heat shock protein 60 mediates neurodegeneration and demyelination in the CNS through a TLR4- and MyD88-dependent pathway.
    Rosenberger K; Dembny P; Derkow K; Engel O; Krüger C; Wolf SA; Kettenmann H; Schott E; Meisel A; Lehnardt S
    Mol Neurodegener; 2015 Feb; 10():5. PubMed ID: 25887709
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Fas/FasL Contributes to HSV-1 Brain Infection and Neuroinflammation.
    Krzyzowska M; Kowalczyk A; Skulska K; Thörn K; Eriksson K
    Front Immunol; 2021; 12():714821. PubMed ID: 34526992
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Unc93B1 biases Toll-like receptor responses to nucleic acid in dendritic cells toward DNA- but against RNA-sensing.
    Fukui R; Saitoh S; Matsumoto F; Kozuka-Hata H; Oyama M; Tabeta K; Beutler B; Miyake K
    J Exp Med; 2009 Jun; 206(6):1339-50. PubMed ID: 19451267
    [TBL] [Abstract][Full Text] [Related]  

  • 18. UNC93B1 mediates host resistance to infection with Toxoplasma gondii.
    Melo MB; Kasperkovitz P; Cerny A; Könen-Waisman S; Kurt-Jones EA; Lien E; Beutler B; Howard JC; Golenbock DT; Gazzinelli RT
    PLoS Pathog; 2010 Aug; 6(8):e1001071. PubMed ID: 20865117
    [TBL] [Abstract][Full Text] [Related]  

  • 19. TRAIL Mediates Neuronal Death in AUD: A Link between Neuroinflammation and Neurodegeneration.
    Qin L; Zou J; Barnett A; Vetreno RP; Crews FT; Coleman LG
    Int J Mol Sci; 2021 Mar; 22(5):. PubMed ID: 33806288
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Complexity of the microglial activation pathways that drive innate host responses during lethal alphavirus encephalitis in mice.
    Esen N; Blakely PK; Rainey-Barger EK; Irani DN
    ASN Neuro; 2012 May; 4(4):207-21. PubMed ID: 22471445
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.