These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

139 related articles for article (PubMed ID: 34597817)

  • 1. Towards quantification and differentiation of protein aggregates and silicone oil droplets in the low micrometer and submicrometer size range by using oil-immersion flow imaging microscopy and convolutional neural networks.
    Umar M; Krause N; Hawe A; Simmel F; Menzen T
    Eur J Pharm Biopharm; 2021 Dec; 169():97-102. PubMed ID: 34597817
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Oil-Immersion Flow Imaging Microscopy for Quantification and Morphological Characterization of Submicron Particles in Biopharmaceuticals.
    Krause N; Kuhn S; Frotscher E; Nikels F; Hawe A; Garidel P; Menzen T
    AAPS J; 2021 Jan; 23(1):13. PubMed ID: 33398482
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Characterization of Protein Aggregates, Silicone Oil Droplets, and Protein-Silicone Interactions Using Imaging Flow Cytometry.
    Probst C
    J Pharm Sci; 2020 Jan; 109(1):364-374. PubMed ID: 31136765
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Image Classification of Degraded Polysorbate, Protein and Silicone Oil Sub-Visible Particles Detected by Flow-Imaging Microscopy in Biopharmaceuticals Using a Convolutional Neural Network Model.
    Fedorowicz FM; Chalus P; Kirschenbühler K; Drewes S; Koulov A
    J Pharm Sci; 2023 Dec; 112(12):3099-3108. PubMed ID: 37422283
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Flow cytometry: a promising technique for the study of silicone oil-induced particulate formation in protein formulations.
    Ludwig DB; Trotter JT; Gabrielson JP; Carpenter JF; Randolph TW
    Anal Biochem; 2011 Mar; 410(2):191-9. PubMed ID: 21146492
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Evaluation of aggregate and silicone-oil counts in pre-filled siliconized syringes: An orthogonal study characterising the entire subvisible size range.
    Shah M; Rattray Z; Day K; Uddin S; Curtis R; van der Walle CF; Pluen A
    Int J Pharm; 2017 Mar; 519(1-2):58-66. PubMed ID: 28089934
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Characterizing Silicone Oil-Induced Protein Aggregation with Stimulated Raman Scattering Imaging.
    Wong B; Zhao X; Su Y; Ouyang H; Rhodes T; Xu W; Xi H; Fu D
    Mol Pharm; 2023 Aug; 20(8):4268-4276. PubMed ID: 37382286
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Quantification and characterization of micrometer and submicrometer subvisible particles in protein therapeutics by use of a suspended microchannel resonator.
    Patel AR; Lau D; Liu J
    Anal Chem; 2012 Aug; 84(15):6833-40. PubMed ID: 22794526
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A Random Forest Approach for Counting Silicone Oil Droplets and Protein Particles in Antibody Formulations Using Flow Microscopy.
    Saggu M; Patel AR; Koulis T
    Pharm Res; 2017 Feb; 34(2):479-491. PubMed ID: 27995522
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Discrimination between silicone oil droplets and protein aggregates in biopharmaceuticals: a novel multiparametric image filter for sub-visible particles in microflow imaging analysis.
    Strehl R; Rombach-Riegraf V; Diez M; Egodage K; Bluemel M; Jeschke M; Koulov AV
    Pharm Res; 2012 Feb; 29(2):594-602. PubMed ID: 21948455
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A Collaborative Study on the Classification of Silicone Oil Droplets and Protein Particles Using Flow Imaging Method.
    Shibata H; Terabe M; Shibano Y; Saitoh S; Takasugi T; Hayashi Y; Okabe S; Yamaguchi Y; Yasukawa H; Suetomo H; Miyanabe K; Ohbayashi N; Akimaru M; Saito S; Ito D; Nakano A; Kojima S; Miyahara Y; Sasaki K; Maruno T; Noda M; Kiyoshi M; Harazono A; Torisu T; Uchiyama S; Ishii-Watabe A
    J Pharm Sci; 2022 Oct; 111(10):2745-2757. PubMed ID: 35839866
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Evaluation of Incremental Siliconization Levels on Soluble Aggregates, Submicron and Subvisible Particles in a Prefilled Syringe Product.
    Bai S; Landsman P; Spencer A; DeCollibus D; Vega F; Temel DB; Houde D; Henderson O; Brader ML
    J Pharm Sci; 2016 Jan; 105(1):50-63. PubMed ID: 26852839
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Automatic Identification of the Stress Sources of Protein Aggregates Using Flow Imaging Microscopy Images.
    Gambe-Gilbuena A; Shibano Y; Krayukhina E; Torisu T; Uchiyama S
    J Pharm Sci; 2020 Jan; 109(1):614-623. PubMed ID: 31669608
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Utility of Three Flow Imaging Microscopy Instruments for Image Analysis in Evaluating four Types of Subvisible Particle in Biopharmaceuticals.
    Nishiumi H; Deiringer N; Krause N; Yoneda S; Torisu T; Menzen T; Friess W; Uchiyama S
    J Pharm Sci; 2022 Nov; 111(11):3017-3028. PubMed ID: 35948157
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Backgrounded Membrane Imaging (BMI) for High-Throughput Characterization of Subvisible Particles During Biopharmaceutical Drug Product Development.
    Helbig C; Ammann G; Menzen T; Friess W; Wuchner K; Hawe A
    J Pharm Sci; 2020 Jan; 109(1):264-276. PubMed ID: 30914272
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Micro-flow imaging and resonant mass measurement (Archimedes)--complementary methods to quantitatively differentiate protein particles and silicone oil droplets.
    Weinbuch D; Zölls S; Wiggenhorn M; Friess W; Winter G; Jiskoot W; Hawe A
    J Pharm Sci; 2013 Jul; 102(7):2152-65. PubMed ID: 23625851
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Applying Pattern Recognition as a Robust Approach for Silicone Oil Droplet Identification in Flow-Microscopy Images of Protein Formulations.
    Chen XG; Graužinytė M; van der Vaart AW; Boll B
    J Pharm Sci; 2021 Apr; 110(4):1643-1651. PubMed ID: 33122049
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Advanced Characterization of Silicone Oil Droplets in Protein Therapeutics Using Artificial Intelligence Analysis of Imaging Flow Cytometry Data.
    Probst C; Zayats A; Venkatachalam V; Davidson B
    J Pharm Sci; 2020 Oct; 109(10):2996-3005. PubMed ID: 32673625
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Convolutional Neural Networks Enable Highly Accurate and Automated Subvisible Particulate Classification of Biopharmaceuticals.
    Wang S; Liaw A; Chen YM; Su Y; Skomski D
    Pharm Res; 2023 Jun; 40(6):1447-1457. PubMed ID: 36471026
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Improving Diameter Accuracy for Dynamic Imaging Microscopy for Different Particle Types.
    Cavicchi RE; Ripple DC;
    J Pharm Sci; 2020 Jan; 109(1):488-495. PubMed ID: 31628920
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.