161 related articles for article (PubMed ID: 34607932)
1. Efficacy of Rac and Cdc42 Inhibitor MBQ-167 in Triple-negative Breast Cancer.
Cruz-Collazo A; Ruiz-Calderon JF; Picon H; Borrero-Garcia LD; Lopez I; Castillo-Pichardo L; Del Mar Maldonado M; Duconge J; Medina JI; Bayro MJ; Hernández-O'Farrill E; Vlaar CP; Dharmawardhane S
Mol Cancer Ther; 2021 Dec; 20(12):2420-2432. PubMed ID: 34607932
[TBL] [Abstract][Full Text] [Related]
2. Characterization of a Dual Rac/Cdc42 Inhibitor MBQ-167 in Metastatic Cancer.
Humphries-Bickley T; Castillo-Pichardo L; Hernandez-O'Farrill E; Borrero-Garcia LD; Forestier-Roman I; Gerena Y; Blanco M; Rivera-Robles MJ; Rodriguez-Medina JR; Cubano LA; Vlaar CP; Dharmawardhane S
Mol Cancer Ther; 2017 May; 16(5):805-818. PubMed ID: 28450422
[TBL] [Abstract][Full Text] [Related]
3. RAC1 GTP-ase signals Wnt-beta-catenin pathway mediated integrin-directed metastasis-associated tumor cell phenotypes in triple negative breast cancers.
De P; Carlson JH; Jepperson T; Willis S; Leyland-Jones B; Dey N
Oncotarget; 2017 Jan; 8(2):3072-3103. PubMed ID: 27902969
[TBL] [Abstract][Full Text] [Related]
4. Efficacy and delivery strategies of the dual Rac/Cdc42 inhibitor MBQ-167 in HER2 overexpressing breast cancer.
Velázquez-Vega LE; Rivera-Robles M; Sánchez-Álvarez AO; Vivas-Mejía PE; Aponte-Reyes M; Cruz-Collazo AM; Grafals-Ruiz N; Dorta-Estremera S; Hernández-O'Farrill E; Vlaar CP; Dharmawardhane S
Transl Oncol; 2024 Jun; 44():101928. PubMed ID: 38489873
[TBL] [Abstract][Full Text] [Related]
5. Characterization of Novel Derivatives of MBQ-167, an inhibitor of the GTP-binding proteins Rac/Cdc42.
Medina JI; Cruz-Collazo A; Del Mar Maldonado M; Gascot TM; Borrero-Garcia LD; Cooke M; Kazanietz MG; O'Farril EH; Vlaar CP; Dharmawardhane S
Cancer Res Commun; 2022 Dec; 2(12):1711-1726. PubMed ID: 36861094
[TBL] [Abstract][Full Text] [Related]
6. Rac and Cdc42 inhibitors reduce macrophage function in breast cancer preclinical models.
Torres-Sanchez A; Rivera-Robles M; Castillo-Pichardo L; Martínez-Ferrer M; Dorta-Estremera SM; Dharmawardhane S
Front Oncol; 2023; 13():1152458. PubMed ID: 37397366
[TBL] [Abstract][Full Text] [Related]
7. Integrin α5 down-regulation by miR-205 suppresses triple negative breast cancer stemness and metastasis by inhibiting the Src/Vav2/Rac1 pathway.
Xiao Y; Li Y; Tao H; Humphries B; Li A; Jiang Y; Yang C; Luo R; Wang Z
Cancer Lett; 2018 Oct; 433():199-209. PubMed ID: 29964204
[TBL] [Abstract][Full Text] [Related]
8. Rac1 and Rac3 isoform activation is involved in the invasive and metastatic phenotype of human breast cancer cells.
Baugher PJ; Krishnamoorthy L; Price JE; Dharmawardhane SF
Breast Cancer Res; 2005; 7(6):R965-74. PubMed ID: 16280046
[TBL] [Abstract][Full Text] [Related]
9. Characterization of EHop-016, novel small molecule inhibitor of Rac GTPase.
Montalvo-Ortiz BL; Castillo-Pichardo L; Hernández E; Humphries-Bickley T; De la Mota-Peynado A; Cubano LA; Vlaar CP; Dharmawardhane S
J Biol Chem; 2012 Apr; 287(16):13228-38. PubMed ID: 22383527
[TBL] [Abstract][Full Text] [Related]
10. A Rac1/Cdc42 GTPase-specific small molecule inhibitor suppresses growth of primary human prostate cancer xenografts and prolongs survival in mice.
Zins K; Lucas T; Reichl P; Abraham D; Aharinejad S
PLoS One; 2013; 8(9):e74924. PubMed ID: 24040362
[TBL] [Abstract][Full Text] [Related]
11. Excellent effects and possible mechanisms of action of a new antibody-drug conjugate against EGFR-positive triple-negative breast cancer.
Zhou DD; Bai WQ; Zhai XT; Sun LP; Zhen YS; Li ZR; Miao QF
Mil Med Res; 2021 Dec; 8(1):63. PubMed ID: 34879870
[TBL] [Abstract][Full Text] [Related]
12. Targeting Cdc42 with the anticancer compound MBQ-167 inhibits cell polarity and growth in the budding yeast S. cerevisiae.
Rivera-Robles MJ; Medina-Velázquez J; Asencio-Torres GM; González-Crespo S; Rymond BC; Rodríguez-Medina J; Dharmawardhane S
Small GTPases; 2020 Nov; 11(6):430-440. PubMed ID: 29969362
[TBL] [Abstract][Full Text] [Related]
13. Maspin controls mammary tumor cell migration through inhibiting Rac1 and Cdc42, but not the RhoA GTPase.
Shi HY; Stafford LJ; Liu Z; Liu M; Zhang M
Cell Motil Cytoskeleton; 2007 May; 64(5):338-46. PubMed ID: 17301947
[TBL] [Abstract][Full Text] [Related]
14. Two distinct mTORC2-dependent pathways converge on Rac1 to drive breast cancer metastasis.
Morrison Joly M; Williams MM; Hicks DJ; Jones B; Sanchez V; Young CD; Sarbassov DD; Muller WJ; Brantley-Sieders D; Cook RS
Breast Cancer Res; 2017 Jun; 19(1):74. PubMed ID: 28666462
[TBL] [Abstract][Full Text] [Related]
15. The Rac inhibitor HV-107 as a potential therapeutic for metastatic breast cancer.
Crespo GV; Ortiz J; O'Farrill EH; Vlaar CP; Inyushin M; Kucheryavykh Y; Kucheryavykh L
Mol Med; 2023 Jun; 29(1):75. PubMed ID: 37316799
[TBL] [Abstract][Full Text] [Related]
16. Zhuidu Formula suppresses the migratory and invasive properties of triple-negative breast cancer cells via dual signaling pathways of RhoA/ROCK and CDC42/MRCK.
Wu Q; Ma X; Jin Z; Ni R; Pan Y; Yang G
J Ethnopharmacol; 2023 Oct; 315():116644. PubMed ID: 37196814
[TBL] [Abstract][Full Text] [Related]
17. R-Ketorolac Targets Cdc42 and Rac1 and Alters Ovarian Cancer Cell Behaviors Critical for Invasion and Metastasis.
Guo Y; Kenney SR; Muller CY; Adams S; Rutledge T; Romero E; Murray-Krezan C; Prekeris R; Sklar LA; Hudson LG; Wandinger-Ness A
Mol Cancer Ther; 2015 Oct; 14(10):2215-27. PubMed ID: 26206334
[TBL] [Abstract][Full Text] [Related]
18. Anti-tumor and anti-metastasis efficacy of E6201, a MEK1 inhibitor, in preclinical models of triple-negative breast cancer.
Lee J; Lim B; Pearson T; Choi K; Fuson JA; Bartholomeusz C; Paradiso LJ; Myers T; Tripathy D; Ueno NT
Breast Cancer Res Treat; 2019 Jun; 175(2):339-351. PubMed ID: 30826934
[TBL] [Abstract][Full Text] [Related]
19. MicroRNA-200b targets protein kinase Cα and suppresses triple-negative breast cancer metastasis.
Humphries B; Wang Z; Oom AL; Fisher T; Tan D; Cui Y; Jiang Y; Yang C
Carcinogenesis; 2014 Oct; 35(10):2254-63. PubMed ID: 24925028
[TBL] [Abstract][Full Text] [Related]
20. Regulation of phosphorylation pathways by p21 GTPases. The p21 Ras-related Rho subfamily and its role in phosphorylation signalling pathways.
Lim L; Manser E; Leung T; Hall C
Eur J Biochem; 1996 Dec; 242(2):171-85. PubMed ID: 8973630
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
