These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

151 related articles for article (PubMed ID: 34609851)

  • 1. High-Content Phenotypic Screen of a Focused TCAMS Drug Library Identifies Novel Disruptors of the Malaria Parasite Calcium Dynamics.
    Chia W; Gomez-Lorenzo MG; Castellote I; Tong JX; Chandramohanadas R; Thu Chu TT; Shen W; Go ML; de Cozar C; Crespo B; Almela MJ; Neria-Serrano F; Franco V; Gamo FJ; Tan KSW
    ACS Chem Biol; 2021 Nov; 16(11):2348-2372. PubMed ID: 34609851
    [TBL] [Abstract][Full Text] [Related]  

  • 2. High-Content Screening of the Medicines for Malaria Venture Pathogen Box for Plasmodium falciparum Digestive Vacuole-Disrupting Molecules Reveals Valuable Starting Points for Drug Discovery.
    Tong JX; Chandramohanadas R; Tan KS
    Antimicrob Agents Chemother; 2018 Mar; 62(3):. PubMed ID: 29311064
    [No Abstract]   [Full Text] [Related]  

  • 3. Considerations on the mechanism of action of artemisinin antimalarials: part 1--the 'carbon radical' and 'heme' hypotheses.
    Haynes RK; Cheu KW; N'Da D; Coghi P; Monti D
    Infect Disord Drug Targets; 2013 Aug; 13(4):217-77. PubMed ID: 24304352
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A Variant PfCRT Isoform Can Contribute to
    Dhingra SK; Redhi D; Combrinck JM; Yeo T; Okombo J; Henrich PP; Cowell AN; Gupta P; Stegman ML; Hoke JM; Cooper RA; Winzeler E; Mok S; Egan TJ; Fidock DA
    mBio; 2017 May; 8(3):. PubMed ID: 28487425
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Identification via a Parallel Hit Progression Strategy of Improved Small Molecule Inhibitors of the Malaria Purine Uptake Transporter that Inhibit
    Sosa Y; Deniskin R; Frame IJ; Steiginga MS; Bandyopadhyay D; Graybill TL; Kallal LA; Ouellette MT; Pope AJ; Widdowson KL; Young RJ; Akabas MH
    ACS Infect Dis; 2019 Oct; 5(10):1738-1753. PubMed ID: 31373203
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Novel 2-Phenoxyanilide Congeners Derived from a Hit Structure of the TCAMS: Synthesis and Evaluation of Their in Vitro Activity against Plasmodium falciparum.
    Weidner T; Nasereddin A; Preu L; Grünefeld J; Dzikowski R; Kunick C
    Molecules; 2016 Feb; 21(2):. PubMed ID: 26901174
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A Redox-Active Fluorescent pH Indicator for Detecting Plasmodium falciparum Strains with Reduced Responsiveness to Quinoline Antimalarial Drugs.
    Jida M; Sanchez CP; Urgin K; Ehrhardt K; Mounien S; Geyer A; Elhabiri M; Lanzer M; Davioud-Charvet E
    ACS Infect Dis; 2017 Feb; 3(2):119-131. PubMed ID: 28183182
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Discovery of Dual-Stage Malaria Inhibitors with New Targets.
    Raphemot R; Lafuente-Monasterio MJ; Gamo-Benito FJ; Clardy J; Derbyshire ER
    Antimicrob Agents Chemother; 2015 Dec; 60(3):1430-7. PubMed ID: 26666931
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A New Set of Chemical Starting Points with Plasmodium falciparum Transmission-Blocking Potential for Antimalarial Drug Discovery.
    Almela MJ; Lozano S; Lelièvre J; Colmenarejo G; Coterón JM; Rodrigues J; Gonzalez C; Herreros E
    PLoS One; 2015; 10(8):e0135139. PubMed ID: 26317851
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Drug-induced permeabilization of parasite's digestive vacuole is a key trigger of programmed cell death in Plasmodium falciparum.
    Ch'ng JH; Liew K; Goh AS; Sidhartha E; Tan KS
    Cell Death Dis; 2011 Oct; 2(10):e216. PubMed ID: 21993392
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis and biological evaluation of benzhydryl-based antiplasmodial agents possessing Plasmodium falciparum chloroquine resistance transporter (PfCRT) inhibitory activity.
    Relitti N; Federico S; Pozzetti L; Butini S; Lamponi S; Taramelli D; D'Alessandro S; Martin RE; Shafik SH; Summers RL; Babij SK; Habluetzel A; Tapanelli S; Caldelari R; Gemma S; Campiani G
    Eur J Med Chem; 2021 Apr; 215():113227. PubMed ID: 33601312
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Antiplasmodial profile of selected compounds from Malaria Box: in vitro evaluation, speed of action and drug combination studies.
    de Souza GE; Bueno RV; de Souza JO; Zanini CL; Cruz FC; Oliva G; Guido RVC; Aguiar ACC
    Malar J; 2019 Dec; 18(1):447. PubMed ID: 31888654
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Design, economical synthesis and antiplasmodial evaluation of vanillin derived allylated chalcones and their marked synergism with artemisinin against chloroquine resistant strains of Plasmodium falciparum.
    Sharma N; Mohanakrishnan D; Sharma UK; Kumar R; Richa ; Sinha AK; Sahal D
    Eur J Med Chem; 2014 May; 79():350-68. PubMed ID: 24747290
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Molecular Mechanisms for Drug Hypersensitivity Induced by the Malaria Parasite's Chloroquine Resistance Transporter.
    Richards SN; Nash MN; Baker ES; Webster MW; Lehane AM; Shafik SH; Martin RE
    PLoS Pathog; 2016 Jul; 12(7):e1005725. PubMed ID: 27441371
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Facile synthesis of vanillin-based novel bischalcones identifies one that induces apoptosis and displays synergy with Artemisinin in killing chloroquine resistant Plasmodium falciparum.
    Sharma UK; Mohanakrishnan D; Sharma N; Equbal D; Sahal D; Sinha AK
    Eur J Med Chem; 2018 Jul; 155():623-638. PubMed ID: 29929118
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Combating multi-drug resistant malaria parasite by inhibiting falcipain-2 and heme-polymerization: Artemisinin-peptidyl vinyl phosphonate hybrid molecules as new antimalarials.
    Aratikatla EK; Kalamuddin M; Rana KC; Datta G; Asad M; Sundararaman S; Malhotra P; Mohmmed A; Bhattacharya AK
    Eur J Med Chem; 2021 Aug; 220():113454. PubMed ID: 33901900
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Uptake of a fluorescently tagged chloroquine analogue is reduced in CQ-resistant compared to CQ-sensitive Plasmodium falciparum parasites.
    Reiling SJ; Rohrbach P
    Malar J; 2019 Oct; 18(1):342. PubMed ID: 31590674
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A high-content phenotypic screen reveals the disruptive potency of quinacrine and 3',4'-dichlorobenzamil on the digestive vacuole of Plasmodium falciparum.
    Lee YQ; Goh AS; Ch'ng JH; Nosten FH; Preiser PR; Pervaiz S; Yadav SK; Tan KS
    Antimicrob Agents Chemother; 2014; 58(1):550-8. PubMed ID: 24217693
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Viability Screen of LOPAC
    Tong JX; Ang SEL; Tan EHN; Tan KSW
    Antimicrob Agents Chemother; 2019 Apr; 63(4):. PubMed ID: 30718250
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Inhibition of glutathione-dependent degradation of heme by chloroquine and amodiaquine as a possible basis for their antimalarial mode of action.
    Ginsburg H; Famin O; Zhang J; Krugliak M
    Biochem Pharmacol; 1998 Nov; 56(10):1305-13. PubMed ID: 9825729
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.