BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

203 related articles for article (PubMed ID: 34615725)

  • 1. A Phase I, Open-Label, Dose-Escalation Study of the OX40 Agonist Ivuxolimab in Patients with Locally Advanced or Metastatic Cancers.
    Diab A; Hamid O; Thompson JA; Ros W; Eskens FALM; Doi T; Hu-Lieskovan S; Klempner SJ; Ganguly B; Fleener C; Wang X; Joh T; Liao K; Salek-Ardakani S; Taylor CT; Chou J; El-Khoueiry AB
    Clin Cancer Res; 2022 Jan; 28(1):71-83. PubMed ID: 34615725
    [TBL] [Abstract][Full Text] [Related]  

  • 2. First-in-human study of an OX40 (ivuxolimab) and 4-1BB (utomilumab) agonistic antibody combination in patients with advanced solid tumors.
    Hamid O; Chiappori AA; Thompson JA; Doi T; Hu-Lieskovan S; Eskens FALM; Ros W; Diab A; Spano JP; Rizvi NA; Wasser JS; Angevin E; Ott PA; Forgie A; Yang W; Guo C; Chou J; El-Khoueiry AB
    J Immunother Cancer; 2022 Oct; 10(10):. PubMed ID: 36302562
    [TBL] [Abstract][Full Text] [Related]  

  • 3. First-in-human phase I/II, open-label study of the anti-OX40 agonist INCAGN01949 in patients with advanced solid tumors.
    Davis EJ; Martin-Liberal J; Kristeleit R; Cho DC; Blagden SP; Berthold D; Cardin DB; Vieito M; Miller RE; Hari Dass P; Orcurto A; Spencer K; Janik JE; Clark J; Condamine T; Pulini J; Chen X; Mehnert JM
    J Immunother Cancer; 2022 Oct; 10(10):. PubMed ID: 36316061
    [TBL] [Abstract][Full Text] [Related]  

  • 4. First-in-human phase I study of the OX40 agonist GSK3174998 with or without pembrolizumab in patients with selected advanced solid tumors (ENGAGE-1).
    Postel-Vinay S; Lam VK; Ros W; Bauer TM; Hansen AR; Cho DC; Stephen Hodi F; Schellens JHM; Litton JK; Aspeslagh S; Autio KA; Opdam FL; McKean M; Somaiah N; Champiat S; Altan M; Spreafico A; Rahma O; Paul EM; Ahlers CM; Zhou H; Struemper H; Gorman SA; Watmuff M; Yablonski KM; Yanamandra N; Chisamore MJ; Schmidt EV; Hoos A; Marabelle A; Weber JS; Heymach JV
    J Immunother Cancer; 2023 Mar; 11(3):. PubMed ID: 36927527
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Safety and Clinical Activity of MEDI0562, a Humanized OX40 Agonist Monoclonal Antibody, in Adult Patients with Advanced Solid Tumors.
    Glisson BS; Leidner RS; Ferris RL; Powderly J; Rizvi NA; Keam B; Schneider R; Goel S; Ohr JP; Burton J; Zheng Y; Eck S; Gribbin M; Streicher K; Townsley DM; Patel SP
    Clin Cancer Res; 2020 Oct; 26(20):5358-5367. PubMed ID: 32816951
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Avelumab for metastatic or locally advanced previously treated solid tumours (JAVELIN Solid Tumor): a phase 1a, multicohort, dose-escalation trial.
    Heery CR; O'Sullivan-Coyne G; Madan RA; Cordes L; Rajan A; Rauckhorst M; Lamping E; Oyelakin I; Marté JL; Lepone LM; Donahue RN; Grenga I; Cuillerot JM; Neuteboom B; Heydebreck AV; Chin K; Schlom J; Gulley JL
    Lancet Oncol; 2017 May; 18(5):587-598. PubMed ID: 28373007
    [TBL] [Abstract][Full Text] [Related]  

  • 7. First-In-Human Phase I Study of the OX40 Agonist MOXR0916 in Patients with Advanced Solid Tumors.
    Kim TW; Burris HA; de Miguel Luken MJ; Pishvaian MJ; Bang YJ; Gordon M; Awada A; Camidge DR; Hodi FS; McArthur GA; Miller WH; Cervantes A; Chow LQ; Lesokhin AM; Rutten A; Sznol M; Rishipathak D; Chen SC; Stefanich E; Pourmohamad T; Anderson M; Kim J; Huseni M; Rhee I; Siu LL
    Clin Cancer Res; 2022 Aug; 28(16):3452-3463. PubMed ID: 35699599
    [TBL] [Abstract][Full Text] [Related]  

  • 8. OX40 is a potent immune-stimulating target in late-stage cancer patients.
    Curti BD; Kovacsovics-Bankowski M; Morris N; Walker E; Chisholm L; Floyd K; Walker J; Gonzalez I; Meeuwsen T; Fox BA; Moudgil T; Miller W; Haley D; Coffey T; Fisher B; Delanty-Miller L; Rymarchyk N; Kelly T; Crocenzi T; Bernstein E; Sanborn R; Urba WJ; Weinberg AD
    Cancer Res; 2013 Dec; 73(24):7189-7198. PubMed ID: 24177180
    [TBL] [Abstract][Full Text] [Related]  

  • 9. OX40 agonist therapy enhances CD8 infiltration and decreases immune suppression in the tumor.
    Gough MJ; Ruby CE; Redmond WL; Dhungel B; Brown A; Weinberg AD
    Cancer Res; 2008 Jul; 68(13):5206-15. PubMed ID: 18593921
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Pamiparib in combination with tislelizumab in patients with advanced solid tumours: results from the dose-escalation stage of a multicentre, open-label, phase 1a/b trial.
    Friedlander M; Meniawy T; Markman B; Mileshkin L; Harnett P; Millward M; Lundy J; Freimund A; Norris C; Mu S; Wu J; Paton V; Gao B
    Lancet Oncol; 2019 Sep; 20(9):1306-1315. PubMed ID: 31378459
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Safety, Tolerability, and Potential Clinical Activity of a Glucocorticoid-Induced TNF Receptor-Related Protein Agonist Alone or in Combination With Nivolumab for Patients With Advanced Solid Tumors: A Phase 1/2a Dose-Escalation and Cohort-Expansion Clinical Trial.
    Heinhuis KM; Carlino M; Joerger M; Di Nicola M; Meniawy T; Rottey S; Moreno V; Gazzah A; Delord JP; Paz-Ares L; Britschgi C; Schilder RJ; O'Byrne K; Curigliano G; Romano E; Patah P; Wang R; Liu Y; Bajaj G; Siu LL
    JAMA Oncol; 2020 Jan; 6(1):100-107. PubMed ID: 31697308
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A Phase 1a/b Open-Label, Dose-Escalation Study of Etigilimab Alone or in Combination with Nivolumab in Patients with Locally Advanced or Metastatic Solid Tumors.
    Mettu NB; Ulahannan SV; Bendell JC; Garrido-Laguna I; Strickler JH; Moore KN; Stagg R; Kapoun AM; Faoro L; Sharma S
    Clin Cancer Res; 2022 Mar; 28(5):882-892. PubMed ID: 34844977
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Tisotumab vedotin in patients with advanced or metastatic solid tumours (InnovaTV 201): a first-in-human, multicentre, phase 1-2 trial.
    de Bono JS; Concin N; Hong DS; Thistlethwaite FC; Machiels JP; Arkenau HT; Plummer R; Jones RH; Nielsen D; Windfeld K; Ghatta S; Slomovitz BM; Spicer JF; Yachnin J; Ang JE; Mau-Sørensen PM; Forster MD; Collins D; Dean E; Rangwala RA; Lassen U
    Lancet Oncol; 2019 Mar; 20(3):383-393. PubMed ID: 30745090
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Safety and Clinical Activity of MEDI1873, a Novel GITR Agonist, in Advanced Solid Tumors.
    Balmanoukian AS; Infante JR; Aljumaily R; Naing A; Chintakuntlawar AV; Rizvi NA; Ross HJ; Gordon M; Mallinder PR; Elgeioushi N; González-García I; Standifer N; Cann J; Durham N; Rahimian S; Kumar R; Denlinger CS
    Clin Cancer Res; 2020 Dec; 26(23):6196-6203. PubMed ID: 32887725
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Tolerability and activity of ublituximab, umbralisib, and ibrutinib in patients with chronic lymphocytic leukaemia and non-Hodgkin lymphoma: a phase 1 dose escalation and expansion trial.
    Nastoupil LJ; Lunning MA; Vose JM; Schreeder MT; Siddiqi T; Flowers CR; Cohen JB; Burger JA; Wierda WG; O'Brien S; Sportelli P; Miskin HP; Purdom MA; Weiss MS; Fowler NH
    Lancet Haematol; 2019 Feb; 6(2):e100-e109. PubMed ID: 30709431
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Neoadjuvant anti-OX40 (MEDI6469) therapy in patients with head and neck squamous cell carcinoma activates and expands antigen-specific tumor-infiltrating T cells.
    Duhen R; Ballesteros-Merino C; Frye AK; Tran E; Rajamanickam V; Chang SC; Koguchi Y; Bifulco CB; Bernard B; Leidner RS; Curti BD; Fox BA; Urba WJ; Bell RB; Weinberg AD
    Nat Commun; 2021 Feb; 12(1):1047. PubMed ID: 33594075
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Assessment of Subcutaneous vs Intravenous Administration of Anti-PD-1 Antibody PF-06801591 in Patients With Advanced Solid Tumors: A Phase 1 Dose-Escalation Trial.
    Johnson ML; Braiteh F; Grilley-Olson JE; Chou J; Davda J; Forgie A; Li R; Jacobs I; Kazazi F; Hu-Lieskovan S
    JAMA Oncol; 2019 Jul; 5(7):999-1007. PubMed ID: 31145415
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Combined targeting of costimulatory (OX40) and coinhibitory (CTLA-4) pathways elicits potent effector T cells capable of driving robust antitumor immunity.
    Redmond WL; Linch SN; Kasiewicz MJ
    Cancer Immunol Res; 2014 Feb; 2(2):142-53. PubMed ID: 24778278
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Evorpacept alone and in combination with pembrolizumab or trastuzumab in patients with advanced solid tumours (ASPEN-01): a first-in-human, open-label, multicentre, phase 1 dose-escalation and dose-expansion study.
    Lakhani NJ; Chow LQM; Gainor JF; LoRusso P; Lee KW; Chung HC; Lee J; Bang YJ; Hodi FS; Kim WS; Santana-Davila R; Fanning P; Squifflet P; Jin F; Kuo TC; Wan HI; Pons J; Randolph SS; Messersmith WA
    Lancet Oncol; 2021 Dec; 22(12):1740-1751. PubMed ID: 34793719
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The small molecule TGF-β signaling inhibitor SM16 synergizes with agonistic OX40 antibody to suppress established mammary tumors and reduce spontaneous metastasis.
    Garrison K; Hahn T; Lee WC; Ling LE; Weinberg AD; Akporiaye ET
    Cancer Immunol Immunother; 2012 Apr; 61(4):511-21. PubMed ID: 21971588
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.